A5076342773- 3D Printing in Biomedical Research
- Electrospun Nanofibers in Biomedical Applications
- Tissue Engineering and Regenerative Medicine
- Innovative Microfluidic and Catalytic Techniques Innovation
- Neuroscience and Neural Engineering
- Bone Tissue Engineering Materials
- Microfluidic and Capillary Electrophoresis Applications
- Angiogenesis and VEGF in Cancer
- Pancreatic function and diabetes
Warsaw University of Technology
2020-2024
In this study, we have investigated how new composite material (magnetic polyurethane (PU) nanofibers) influences the culture and maturation of cardiomyocyte cells. Magnetic iron (II, III) oxide nanoparticles (Fe3O4, MNPs) were incorporated into nanofiber structure using solution blow spinning (SBS) method, resulting in magnetic mats. These mats characterized by physicochemical, optical (Young's modulus, wettability, surface zeta potential, autofluorescence), properties. It was found that...
Regenerative medicine and stem cells could prove to be an effective solution the problem of treating heart failure caused by ischemic disease. However, further studies on understanding processes which occur during regeneration damaged tissue are needed. Microfluidic systems, provide conditions similar in vivo, useful tools for development new therapies using cells. We investigated how mesenchymal (MSCs) affect metabolic activity cardiac (rat cardiomyoblasts human cardiomyocytes) incubated...
Angiogenesis is the development of new blood vessels from existing vasculature. Its malfunction leads to cancers and cardiovascular diseases qualified by WHO as a leading cause death worldwide. A better understanding mechanisms regulating physiological pathological angiogenesis will potentially contribute developing more effective treatments for those urgent issues. Therefore, main goal following study was design manufacture an angiogenesis-on-a-chip microplatform, including cylindrical...
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Diabetes is a disease associated with the insufficiency of pancreatic endocrine part, consisting mainly islets. Currently, diabetes considered fastest growing civilization disease. Globally, over 440 million people suffer from diabetes, and it estimated that this number will increase to 700 by 2045. Pancreatic islets are complex, highly vascularized mini-organs, only development fully functional islet model could lead progress knowledge about evolution, new therapeutic strategies, generation...