A5023320927- Radiation Therapy and Dosimetry
- Advanced Radiotherapy Techniques
- Nuclear Physics and Applications
- Radiation Detection and Scintillator Technologies
- Radiation Dose and Imaging
- Radiomics and Machine Learning in Medical Imaging
- Radiation Effects in Electronics
- Nuclear reactor physics and engineering
- Radiation Effects and Dosimetry
- Lung Cancer Diagnosis and Treatment
- Advanced X-ray and CT Imaging
- Boron Compounds in Chemistry
- Particle Detector Development and Performance
- Medical Imaging Techniques and Applications
- Breast Cancer Treatment Studies
- Gene expression and cancer classification
- Advanced Thermodynamics and Statistical Mechanics
- Electron and X-Ray Spectroscopy Techniques
- Reconstructive Surgery and Microvascular Techniques
- Quantum Electrodynamics and Casimir Effect
- Wireless Body Area Networks
- Cardiac Imaging and Diagnostics
- Radiation Shielding Materials Analysis
- Particle accelerators and beam dynamics
- Advances in Oncology and Radiotherapy
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2023-2024
Catalan Society of Family and Community Medicine
2024
Hospital Clínic de Barcelona
2019-2024
KU Leuven
2016-2021
Advanced Centre for Treatment, Research and Education in Cancer
2017
École Polytechnique Fédérale de Lausanne
2013-2016
ETH Zurich
2016
Paul Scherrer Institute
2013-2015
Massachusetts General Hospital
2011-2013
Harvard University
2011-2012
Proton, as well other ion, beams applied by electro-magnetic deflection in pencil-beam scanning (PBS) are minimally perturbed and thus can be quantified a priori their fundamental interactions medium. This quantification permits an optimal reduction of characterizing measurements on particular PBS delivery system. The combination will then suffice to fully describe the physical necessary for treatment planning purposes. We consider, proton beams, these derive 'Golden' beam data set. Golden...
The first goal of this paper is to clarify the reference conditions for dosimetry clinical proton beams. A clear distinction made between beam delivery systems which should be calibrated with a spread-out Bragg peak field and those that (pseudo-)monoenergetic beam. For latter, also compares two independent techniques calibrate monitor chambers: absolute (of number protons exiting nozzle) Faraday cup (i.e. determination absorbed dose water under IAEA TRS-398 conditions) an ionization chamber....
This work calculates beam quality correction factors (kQ) in monoenergetic proton beams using detailed Monte Carlo simulation of ionization chambers. It uses the code penh and electronic stopping powers resulting from adoption two different sets mean excitation energy values for water graphite: (i) currently ICRU 37 49 recommended Iw = 75 eV Ig 78 (ii) recently proposed 81.1 eV. Twelve chambers were studied. The k Q calculated I-values found to agree with each other within 1.6% or better....
Despite extensive research in dual-energy computed tomography (CT), single-energy CT (SECT) is still the standard imaging modality proton therapy treatment planning and, this context, stoichiometric calibration method considered to be most accurate establish a relationship between numbers and stopping power. This work revisits SECT for planning, with special emphasis on method. Three different sets of tissue-substitutes known elemental composition (Gammex, CIRS Catphan) were scanned same...
The purpose of this work is to analyze whether the Monte Carlo codes penh, fluka, and geant4/topas are suitable calculate absorbed doses
This work calculates beam quality correction factors ([Formula: see text]) in both modulated and unmodulated proton beams using the Monte Carlo (MC) code [Formula: text]. The latest ICRU 90 recommendations on key data for ionizing-radiation dosimetry were adopted to calculate electronic stopping powers select mean energy create an ion pair dry air text]). For beams, text] calculated middle of a spread-out Bragg peak, while monoenergetic they at entrance region. Fifteen ionization chambers...
This paper uses Monte Carlo simulations to calculate the Spencer–Attix water/medium stopping-power ratios (sw, med) for dosimetry of scanned proton pencil beams. It includes energies from 30 350 MeV and typical detection materials such as air (ionization chambers), radiochromic film, gadolinium oxysulfide (scintillating screens), silicon lithium fluoride. Track-ends particles heavier than protons were found have a negligible effect on water/air air), whereas mean excitation energy values...
This work presents CloudMC, a cloud computing application-developed in Windows Azure®, the platform of Microsoft® cloud-for parallelization Monte Carlo simulations dynamic virtual cluster. CloudMC is web application designed to be independent code which are based-the just need form: input files → executable output files. To study performance with penelope were performed on different instance (virtual machine) sizes, and for number instances. The size was found have no effect simulation...
This paper presents a method to experimentally validate the beam quality correction factors (kQ) tabulated in IAEA TRS-398 for proton beams and determine kQ of non-tabulated ionization chambers (based on already values). The is based exclusively ionometry it consists comparing reading two under same reference conditions Q (60)Co. allows one ratio between chambers. In this work, 7 different chamber models were irradiated (60)Co beams. For latter, both modulated (spread-out Bragg peak field)...
Irradiation log-files store useful information about the plan delivery, and together with independent Monte Carlo dose engine calculations can be used to reduce time needed for patient-specific quality assurance (PSQA). Nonetheless, machine carry an uncertainty associated measurement of spot position intensity that influence correct evaluation treatment delivery. This work addresses problem inclusion these uncertainties final verification Dedicated measurements performed in IBA Proteus Plus...
This paper describes a novel approach to the reference dosimetry of proton pencil beams based on dose-area product (). It depicts calibration large-diameter plane-parallel ionization chamber in terms 60Co beam, Monte Carlo calculation beam quality correction factors—in product—in beams, nuclear halo factors, and experimental determination single beam. new proves be feasible, as it yields values agreement with standard well-established determining absorbed dose water at centre broad...
Abstract The beam quality correction factor, , which corrects for the difference in ionization chamber response between reference and clinical quality, is an integral part of radiation therapy dosimetry. uncertainty one most significant sources dose determination. To improve accuracy available data, four partners calculated factors 10 models linear accelerator beams with voltages ranging from 6 MV to 25 MV, including flattening-filter-free (FFF) beams. software used calculations were EGSnrc...
Purpose: In the present era of cone‐beam CT scanners, use standardized as a surrogate idealized CTDI is strongly discouraged and, consequently, so should be dose‐length product (DLP) an estimate total energy imparted to patient. However, DLP still widely used reference quantity normalize effective dose for given scan protocol mainly because easy‐to‐measure quantity. The aim this article therefore describe method radiation assessment in large single axial scans, which leads straightforward...
For the update of IAEA TRS-398 Code Practice (CoP), global ionization chamber factors (fQ) and beam quality correction (kQ) for air-filled chambers in clinical proton beams have been calculated with different Monte Carlo codes. In this study, average fQ kQ are provided uncertainty these is estimated. Average monoenergetic energies between 60 MeV 250 were derived from published literature. Altogether, 195 six plane-parallel three cylindrical penh, fluka geant4 incorporated. Additionally, a...