Javier Espinosa

ORCID: 0000-0003-0341-2708
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About
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Research Areas
  • Prostate Cancer Treatment and Research
  • Neutropenia and Cancer Infections
  • Hematological disorders and diagnostics
  • Bone health and treatments
  • Advanced Statistical Methods and Models
  • Multi-Criteria Decision Making
  • Economic and Financial Impacts of Cancer
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Radiopharmaceutical Chemistry and Applications
  • Health Systems, Economic Evaluations, Quality of Life
  • Statistical Methods and Bayesian Inference
  • Colorectal Cancer Treatments and Studies
  • Employment and Welfare Studies
  • Cancer Diagnosis and Treatment
  • Blood disorders and treatments
  • Health disparities and outcomes
  • Cancer, Lipids, and Metabolism
  • Lung Cancer Research Studies
  • Lymphoma Diagnosis and Treatment
  • Prostate Cancer Diagnosis and Treatment
  • Hedgehog Signaling Pathway Studies
  • Management of metastatic bone disease
  • Diverticular Disease and Complications
  • Pharmaceutical Economics and Policy
  • Hormonal and reproductive studies

Hospital Universitario de Guadalajara
2005-2024

Willows Veterinary Centre and Referral Service
2022-2024

University of Guayaquil
2024

Universidad de Santiago de Chile
2013-2023

Menescalia Centro Veterinario
2023

Universidad de León
1999-2022

Hospital de León
2022

Hospital General Universitario de Ciudad Real
2014-2019

Hospital General Universitario de Alicante Doctor Balmis
2011-2018

University College London
2018

Xavier Pivot Joseph Gligorov Volkmar Müller Giuseppe Curigliano Ann Knoop and 87 more Sunil Verma Valerie Jenkins Nana Scotto Stuart Osborne Lesley Fallowfield Lesley Fallowfield Valerie Jenkins Justine Kilkerr C. Langridge Kathryn Monson Erik Jakobsen Mette Holck Nielsen Soeren Linnet Ann Knoop Xavier Pivot Hervé Bonnefoi Mireille Mousseau Laurent Zelek Hugues Bourgeois Claudia Lefeuvre Thomas Bachelot Thierry Petit Étienne Brain Christelle Lévy Joseph Gligorov Doris Augustin Heiko Graf Georg Heinrich Hendrik Kroening Sherko Küemmel Volkmar Müller Friedrich Overkamp Tjoung‐Won Park‐Simon Marcus Schmidt Lidia Perlova-Griff Christopher Wolf Marco Colleoni Alberto Ballestrero Antônio Bernardo Angela Stefania Ribecco Luca Gianni Giuseppe Curigliano Elżbieta Brewczyńska Jacek Jassem Vadim Shirinkin Alexey Manikhas В. В. Дворниченко Mikhail Lichinitser Semiglazov Vf Guzel Mukhametshina Irina Bulavina Enrique Espinosa Francisco Carabantes Ocón Guillermo López-Vivanco Javier Salvador Bofill Ignacio Porras Quintela Alfonso Sánchez Muñoz Yolanda Fernández Pérez Javier Espinosa Jose Alvarez Rodrigo Lastra del Prado LuisLa Cruz De Merino José Manuel Pérez García Santos Enrech Francés Per Edlund Bengt Norberg Anna-Karin Wennstig Pehr Lind Nik Hauser Christoph Tausch Celalettin Camcı Fikret Arpacı Hüseyin Abalı Rüçhan Uslu Saad Tahir Duncan Wheatley Stephen Chan Peter Barrett‐Lee Karen McAdam Richard Simcock Russell Burcombe Robert H. El-Maraghi Nadia Califaretti Silvana Spadafora Sandeep Sehdev Amer Sami Sunil Verma

10.1093/annonc/mdu364 article EN publisher-specific-oa Annals of Oncology 2014-07-29

To validate a prognostic score predicting major complications in patients with solid tumors and seemingly stable episodes of febrile neutropenia (FN). The definition clinical stability implies the absence organ dysfunction, abnormalities vital signs, infections.We developed Clinical Index Stable Febrile Neutropenia (CISNE), six explanatory variables associated serious complications: Eastern Cooperative Oncology Group performance status ≥ 2 (2 points), chronic obstructive pulmonary disease (1...

10.1200/jco.2014.57.2347 article EN Journal of Clinical Oncology 2015-01-06

The Spanish ibex (Capra pyrenaica hispanica) population of the "Sierras de Cazorla, Segura y Las Villas" Nature Park (Spain) was isolated as result a severe epidemic sarcoptic mange. In this context, dynamic characteristics disease were analyzed in wild group consisting 35 animals from beginning epizootic (when mating period started) to extinction due Monthly tracking permitted sequential characterization pathology each animal. duration 2 3 mo, evolving and terminating death. Incidence...

10.7589/0090-3558-35.4.647 article EN Journal of Wildlife Diseases 1999-10-01

The study evaluated the rate of reversal Hartmann's operation after initial surgery and its morbidity.A multicentre retrospective was carried out in seven hospitals Valencia area patients who underwent from 2004 to 2008. incidence determined.Four hundred fifty-two mean age 67.5 ± 15.4 years were included, whom 78.8% had an emergency operation. most common diagnosis cancer (58.6%), although diverticulitis predominated setting. At a median follow up 44 months, 159 (35.2%) undergone reversal,...

10.1111/j.1463-1318.2011.02738.x article EN Colorectal Disease 2011-08-01

Chemotherapy and radiotherapy often result in reduced fertility cancer patients. With increasing survival rates, is an important quality-of-life concern for many young Around 70-75% of survivors are interested parenthood but the numbers patients who access preservation techniques prior to treatment significantly lower. Moreover, despite existing guidelines, healthcare professionals do not address issues adequately. There a critical need improvements clinical care ensure well informed about...

10.1007/s12094-016-1587-9 article EN cc-by Clinical & Translational Oncology 2016-11-28

BACKGROUND In spite of the high prevalence cancer in elderly, little information is available about efficacy and toxicity chemotherapy elderly patients. a previous study, authors demonstrated that combination uracil tegafur (UFT) with leucovorin (LV) was active well tolerated patients advanced colorectal carcinoma (ACC). The objective current study to determine this regimen ACC. METHODS Thirty-eight unselected older than 70 years (median age, 74 years) measurable ACC were included. All...

10.1002/(sici)1097-0142(19970515)79:10<1884::aid-cncr7>3.0.co;2-g article EN Cancer 1997-05-15

Febrile neutropenia (FN) is a common dose-limiting toxicity of chemotherapy, with profound impact on the evolution patients cancer, due to potential development serious complications, mortality, delays, and decrease in treatment intensity. This article seeks present an updated clinical guideline, recommendations regarding diagnosis, prevention, febrile adults solid tumors. The aspects covered include how properly approach risk microbial resistances, epidemiological aspects, considerations...

10.1007/s12094-018-1983-4 article EN cc-by Clinical & Translational Oncology 2018-11-23

Abstract We analyze the effect of obesity on incidence hypertension, hyperlipidemia and diabetes in USA using a health production theoretical framework along with bivariate flexible semi-parametric recursive copula model that account for endogeneity. In this approach, effects control variables are flexibly determined additive predictors allow variety effects. Our findings suggest there exist positive significant prevalence all chronic diseases examined. particular, after endogeneity is...

10.1038/s41598-023-28920-6 article EN cc-by Scientific Reports 2023-02-01

Although the prevalence of nonsmall cell lung carcinoma (NSCLC) is high among elderly patients, few data are available regarding efficacy and toxicity chemotherapy in this group patients. Recent reports indicate that single agent therapy with vinorelbine (VNB) or gemcitabine (GEM) may obtain a response rate 20-30% acceptable improvement symptoms quality life. In current study combination GEM VNB patients advanced NSCLC those some contraindication to receiving cisplatin were...

10.1002/(sici)1097-0142(19991015)86:8<1463::aid-cncr12>3.0.co;2-n article EN Cancer 1999-10-15

Gastrointestinal metastases from breast cancer are not common. We present a 58-year-old female diagnosed with lobular some years before whose relapses were gastric and colonic mucosal. Simultaneous extremely rare. To our knowledge, no cases of initial dual affectation have been reported. The patient also showed gastritis by Helicobacter pylori. Invasive carcinoma is the most frequent special type carries specific molecular alterations such as loss expression E-cadherin. Although underlying...

10.2147/bctt.s79506 article EN cc-by-nc Breast Cancer Targets and Therapy 2016-12-01

In oncology, establishing the value of new cancer treatments is challenging. A clear definition different perspectives regarding drivers innovation in oncology required to enable be properly rewarded for they create. The aim this study was analyze views oncologists, health care policy makers, patients, and general population treatments.An exploratory qualitative conducted through structured interviews assess participants' attitudes toward cost outcomes drugs. First, participants were asked...

10.2147/ppa.s93760 article EN cc-by-nc Patient Preference and Adherence 2015-12-01

Because excise taxes are independent of product price, rate hikes predicted to lower the relative cost high-priced goods, encouraging a shift toward their purchase. Using scanner data on cigarette sales from twenty-nine states over six-year period, we examine whether tax encourage flight quality. Results demonstrate that one-cent hike in increases retail prices name-brand and generic cigarettes by exactly one cent. We find no tax-induced substitution name brands but large away carton pack...

10.1177/1091142112460724 article EN Public Finance Review 2012-11-15

We sought to develop and externally validate a nomogram web-based calculator individually predict the development of serious complications in seemingly stable adult patients with solid tumours episodes febrile neutropenia (FN). The data from FINITE study (n=1133) University Salamanca Hospital (USH) FN registry (n=296) were used this tool. main eligibility criterion was presence apparent clinical stability, defined as events without acute organ dysfunction, abnormal vital signs, or major...

10.1038/bjc.2016.118 article EN cc-by-nc-sa British Journal of Cancer 2016-05-01

This paper uses multinomial logit to analyze economic insecurity for C hile and M exico from household surveys. It analyzes the effect changes in well‐being, age, health, wealth, employment status, gender, education have on insecurity. The results show that most significant variable is current exposure adverse events, second third health. events produces great anxiety concern about inability recover these bad events. Older households assign higher probabilities negative prospects are thus...

10.1111/roiw.12052 article EN Review of Income and Wealth 2013-07-29

Abstract Aim: Studies in some countries suggest that cancer pain is often not adequately controlled, but little known about the situation Spain. The objective of this study was to identify medical oncologists’ perceptions management their patients. Methods: Two‐round Delphi survey 24 oncologists from 22 large, geographically diverse hospitals Physicians rated each 150 statements on a Likert scale (1=strongly disagree; 5=strongly agree). mean, standard deviation and frequency replies three...

10.1016/j.ejpain.2006.05.006 article EN European Journal of Pain 2006-07-12
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