A5056213467- Parathyroid Disorders and Treatments
- Cardiovascular Disease and Adiposity
- Cardiovascular Health and Disease Prevention
- Vitamin D Research Studies
- Thyroid Cancer Diagnosis and Treatment
- Thyroid Disorders and Treatments
- Growth Hormone and Insulin-like Growth Factors
- Pituitary Gland Disorders and Treatments
- Cardiovascular Function and Risk Factors
- Diabetes Treatment and Management
- Fish Biology and Ecology Studies
- Fish Ecology and Management Studies
- Media Discourse and Social Analysis
- Adrenal Hormones and Disorders
- Bone health and treatments
- Terrorism, Counterterrorism, and Political Violence
- Metabolism, Diabetes, and Cancer
- Ottoman and Turkish Studies
- Gout, Hyperuricemia, Uric Acid
- Families in Therapy and Culture
- Public Administration and Governance
- Cardiac Imaging and Diagnostics
- Biomarkers in Disease Mechanisms
- Ocular Diseases and Behçet’s Syndrome
- Blood Pressure and Hypertension Studies
Gaziantep Children's Hospital
2024
Düzce Üniversitesi
2011-2023
State Hospital
2023
Sağlık Bilimleri Üniversitesi
2017-2023
Marmara University
2023
Rize Devlet Hastanesi
2023
Gazi University
2023
Small and Medium Enterprises Development Organization
2022
İstanbul Eğitim ve Araştırma Hastanesi
2022
Istanbul Medeniyet University
2013-2020
Parathyroidectomy has ameliorated cardiovascular risk factors in patients with hypercalcemic primary hyperparathyroidism (PHPT), but the effect of parathyroidectomy on normocalcemic PHPT is not exactly known. This case-controlled study aimed to investigate and PHPT. Subjects (n = 35), age- sex-matched 60) control were included. Cardiometabolic disorders investigated traditional cardiometabolic Framingham score (CRS) before 6 months after parathyroidectomy. Diabetes, dyslipidemia,...
Although uric acid (UA) is considered as an antioxidant, the relationship between serum UA levels and cardiovascular diseases not clear yet. Higher brachial artery resting diameter (BD), impaired flow-mediated dilatation (FMD), increased carotid intima-media thickness (IMT), decreased aortic distensibility (AoD), stiffness index (AoSI) elastic modulus (AoEM) are predictors for development and/or progression of atherosclerosis. In this study, BD, FMD, IMT, AoD, AoSI AoEM were studied in...
This retrospective study investigated the effect of adding metformin to pharmacologic insulin dosing in type 1 diabetics on therapy year after treatment compared with patients alone.Twenty-nine adults diabetes who had added their for 12 months were 29 remained insulin-alone therapy.Fifty-eight C peptide negative-type (26 females, mean age: 29.01 ± 7.03 years, BMI: 24.18 3.16 kg/m2) analyzed. Age, sex, body weight, dose requirement, plasma glucose (PG), blood pressure (BP), and lipids did not...
The association between the vitamin D receptor (VDR) gene and gestational diabetes mellitus (GDM) has not been investigated in Turkish pregnant women. We aimed to investigate associations VDR BsmI (rs15444410), ApaI (rs7975232), FokI (rs19735810), TaqI (rs731236) single nucleotide polymorphisms (SNPs) GDM. This case-control study comprised 100 women with GDM 135 without polymorphism was evaluated using Sanger-based DNA sequencing. ApaI, BsmI, SNPs did differ (each, p > 0.05). were associated...
This is the first study to investigate effect of vitamin D receptor ( VDR) gene single-nucleotide polymorphisms on clinicopathologic features papillary thyroid cancer in Turkey. A total 165 patients with and 172 controls were included this case-control study. VDR FokI (rs2228570), BsmI (rs1544410), ApaI (rs7975232), TaqI (rs731236) evaluated using reverse-transcription polymerase chain reaction. BsmI, ApaI, did not differ between group control (p > 0.05, each). associated risk. The CT/TT...
Background Gestational diabetes mellitus (GDM) is a prediabetic state that known to increase the risk of cardiovascular diseases. We have investigated coronary flow velocity reserve (CFVR) and epicardial fat thickness (EFT), left ventricular diastolic function in patients with history previous GDM (p-GDM).Methods Ninety-three women 95 healthy without were recruited. used transthoracic Doppler echocardiography assess CFVR, EFT, function. Insulin resistance each subject was assessed...
Vitamin D deficiency is a common health problem. supplements are used to improve vitamin status; however, there contradictory data related what doses give and how often they should be given. Many studies have investigated the effects of supplementation on muscle strength, but results remain controversial. We aimed compare safety single high-dose with daily low-dose oral colecalciferol 25(OH)D levels strength in postmenopausal women or insufficiency. Sixty healthy who had serum < 20 ng/mL (50...
Pre-pregnancy obesity, gestational diabetes mellitus (GDM), and weight gain (GWG) are associated with each other. This is the first study to investigate whether genetic variants were having GDM, variants-related GDM adiposity including pre-pregnancy obesity excessive GWG in Turkish women.Women (n = 160) without 145) included case-controlled study. Genotyping of HNF1A gene (p.I27L rs1169288, p.98V rs1800574, p.S487N rs2464196), VDR (p.BsmI rs1544410, p.ApaI rs7975232, p.TaqI rs731236, p.FokI...
Abstract Objective Although the cardiovascular system is highly sensitive to thyroid hormones, effects of subtle dysfunction such as subclinical hypothyroidism (SHT) remain unclear. Therefore, we investigated coronary flow reserve (CFR) reflecting microvascular function in patients with SHT. Methods Fifty subjects SHT and 30 control normal serum hormones TSH levels were included this study. Coronary diastolic peak velocities measured at baseline after dipyridamole infusion. CFR was...
Gestational diabetes mellitus (GDM) is defined as glucose intolerance that has begun during pregnancy. Recent studies have proven development of atherosclerosis may be established in this population even without presence type 2 diabetes. For assessment atherosclerosis, epicardial fat thickness (EFT) recently being used a surrogate marker. In study, we aimed to prove women with GDM history are more inclined higher EFT levels than history.Sixty-two patients previous and 33 age- sex-matched...
Aim . This study aimed to compare thyroid functions, autoantibodies, and the existence of nonthyroidal illness syndrome (NTIS) according vitamin D level. Materials Methods The included age- BMI-matched healthy volunteers with without deficiency. In addition, status was evaluated. Results Anti-TPO positivity significantly more common in those severe moderate deficiency, as compared a normal 25(OH)D Furthermore, TSH levels were lower deficiency than there significant weak inverse correlation...
Fifth metacarpal fractures are the most common of hand. These generally treated with conservative methods. The aim this study was to compare radiological and clinical outcomes two treatment methods, functional splint(FMS) ulnar gutter splint(UGS), for fifth neck fractures.A prospective comparative designed assess isolated closed stable neck. In total, 58 patients were included in FMS or UGS after fracture reduction a consecutive order. Angulation, shortening outcome (QuickDASH scores grip...
There are a number of pre-analytical and analytical factors, which cause false results in the complete blood count. The present case identifies cold agglutinins as for mismatch between hematocrit hemoglobin values.70-year old female patient had history cerebrovascular diseases rheumatoid arthritis. During routine laboratory examination, normal leukocyte platelet counts; however, (Hb: 105 g/L) (HCT: 0.214 L/L) were discordant. Hemolysis, lipemia agglutinin evaluated possible reasons...
Nodular thyroid disease is a very common disorder in patients with acromegaly. Insulin-like growth factor-1 (IGF-1) factor, and there correlation between IGF-1 levels volume (TV) There no study investigating the impact of somatostatin analog (SSA) treatment on nodule We aimed to assess change SSA persistent retrospectively analyzed data from 108 consecutive acromegaly who were followed up by our clinic after undergoing surgery 2002 2014. Patients cured excluded. only selected 43 (21 males,...
The molecular basis of the Turkish population with suspected maturity-onset diabetes young (MODY) has not been identified. This is first study to investigate association between HNF1A-gene single-nucleotide polymorphisms (SNPs) and having early-onset, MODY-like mellitus in population. All diabetic patients (N = 565) who presented our clinic 2012 2015 a clinical suspicion MODY were included study. Analysis HNF1A, HNFB, HNF4A, GCK gene mutations was performed using real-time polymerase chain...
Although white-coat hypertension may be present in 25% or more of hypertensive individuals, its prognostic significance and predisposition to end organ damage is unknown. To evaluate whether associated with damage, we compared prognostically relevant measures target-organ among 35 individuals age sex-matched groups sustained normotensive classified by clinical 24-h ambulatory blood pressures.We evaluated left ventricular diastolic function aortic elastic properties hypertension, 50 patients...
Masked hypertension is associated with an increase in cardiovascular risk. Mean platelet volume (MPV), a determinant of function, new risk factor for atherothrombosis. High-sensitive C-reactive protein (CRP) exquisitely sensitive systemic marker inflammatory response. We designed this study to evaluate MPV and CRP masked hypertensive patients compare those essential healthy normotensive individuals. Forty-two untreated patients, 53 age-sex matched 37 individuals were included the study....