A5013439965- Obesity, Physical Activity, Diet
- Diet, Metabolism, and Disease
- Diabetes Management and Research
- Diet and metabolism studies
- Oral microbiology and periodontitis research
- Growth Hormone and Insulin-like Growth Factors
- Birth, Development, and Health
- Cardiovascular Health and Disease Prevention
- Liver Disease Diagnosis and Treatment
- Adipose Tissue and Metabolism
- Pancreatic function and diabetes
- HIV/AIDS oral health manifestations
- Fatty Acid Research and Health
- Ultrasound Imaging and Elastography
- Metabolomics and Mass Spectrometry Studies
- Oral Health Pathology and Treatment
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Parkinson's Disease Mechanisms and Treatments
- Non-Invasive Vital Sign Monitoring
- Lipid metabolism and biosynthesis
- Cardiovascular Function and Risk Factors
- Folate and B Vitamins Research
- Congenital Ear and Nasal Anomalies
- Pharmacology and Obesity Treatment
- Metabolism and Genetic Disorders
Victor Babeș University of Medicine and Pharmacy Timișoara
2007-2022
Spitalul Clinic Judeţean de Urgenţă "Pius Brînzeu" Timişoara
2022
Spitalul Clinic de Recuperare
2015
Population aging is unprecedented, without parallel in the history of humanity. As type 2 diabetes mellitus predominantly more prevalent populations, this creates a major public health burden. Older adults with have highest rates lower-extremity amputation, myocardial infarction, visual impairment, and end-stage renal disease any age group. The aims our study were to assess whether an independent factor for occurrence diabetic neuropathy (DN), evaluate relationship between presence severity...
Few high-performance liquid chromatography–tandem mass spectrometry (LC-MS/MS) methods have been developed for the full quantitation of fatty acids from human plasma without derivatization. Therefore, we propose a method that requires fewer sample preparation steps, which can be used several polyunsaturated in plasma. The offers rapid, accurate, sensitive, and simultaneous quantification omega 3 (α-linolenic, eicosapentaenoic, docosahexaenoic acids) 6 (arachidonic linoleic using LC-MS/MS....
Early detection of all complications childhood obesity is imperative in order to minimize effects. Obesity causes vascular disruptions, including early increased arterial stiffness and high blood pressure. This study's aim assess the reliability pulse wave analysis (PWA) obese children how additional risk factors influence evaluated parameters. We analyzed 55 aged 6-18 years old by measuring their velocity (PWV), augmentation index (AIx), peripheral pressure (SBP, DBP), heart rate, central...
Given the growing obesity rates among children, a more complete evaluation of their potential cardiometabolic risk is needed. Carotid intima-media thickness (CIMT), marker endothelial distress and predictor atherosclerotic progression in adulthood, may day-to-day children at risk. Multiple factors act as additional precipitant causes atherosclerosis. We analyzed 60 patients aged 6–17 years old by measuring CIMT using Aixplorer MACH 30 echography machine automatic measurement software. All...
Polyunsaturated fatty acids (PUFAs) play important roles in health and disease. PUFA levels are influenced by nutrition genetic factors. The relationship between composition red blood cells (RBCs) variations involved metabolism has not been investigated children with obesity. This study evaluated the association several RBCs One hundred ninety-six obesity (101 females, 95 males) were using anthropometric measurements, dietary intakes, plasma RBC quantification, biochemistry, 55 single...
Background Previous genome-wide association studies (GWAS) identified IGF1, IRS1, GCKR, PPARG, GCK1 and KCTD1 as candidate genes for insulin resistance type 2 diabetes (T2D). We investigated the associations of these previously reported common variants in with overweight children from Romania Moldova. Methods Six single nucleotide polymorphisms (SNPs), IGF1 (rs35767), IRS1 (rs2943634), GCKR (rs780094), PPARG (rs1801282), (rs1799884) KCTD15 (rs29941), were genotyped 100 along clinical...
Retinopathy of prematurity (ROP) is known as an abnormal development the blood capillaries from eyes retina, and it met to those infants that were born too early (premature) its name suggests. Bevacizumab or Avastin belongs class monoclonal antibodies a possible treatment for patients who have been diagnosed with recurrent malignant glioma other cancers due behavior bind selectively vascular endothelial growth factor (VEGF). In this study, eye drops based on polyurethane carrier used...
Insulin resistance plays a major role in metabolic syndrome and is recognized as the most common risk factor for non-alcoholic fatty liver disease (NAFLD). Identifying predictors insulin could optimize screening prevention.To evaluate contribution of multiple single nucleotide polymorphisms across genes related to NAFLD choline metabolism, predicting children with obesity.One hundred fifty-three obesity (73 girls), aged 7-18 years, were evaluated within NutriGen Study...
Introduction. Anthropometric measurements are simple clinical tools that can be used for the evaluation of obesity-related cardiometabolic complications. Objective. To identify outcomes and to compare relevance BMI or WHtR early diagnosis in a group obese children adolescents. Material methods. The study included 174 diagnosed with obesity during three year period. (including WHtR) biochemical variables were analyzed. Results. 4.28% overweight, 31.43% 64.29% had extreme obesity. main...
Abstract Background and Aims. Scientists are constantly showing a high interest for the relationship between Periodontal Disease (PD) Diabetes Mellitus (DM). PD, “the sixth complication” of DM is recognized to be chronic gram-negative anaerobic infectious disease. This paper aimed at reviewing evaluating correlations PD from microbiological point view. Treatment implications PD’s management as an important component care reviewed in light current knowledge. Materials Methods. Microbiological...
Introduction. Hypoglycemia with its diverse causes is frequently encountered in the pediatrics pathology, beginning neonatal period and until adolescent one. Through consequences, both, early (seizures, coma) late ones (neurological impairment), hypoglycemia must be identified, prevented, avoided treated. Objectives. To present clinical evolution of a female patient severe, symptomatic even since period. Since birth, value glycaemia presents fluctuant dynamic, isolated decrease does not...
Introducere. Hipoglicemia cu diversele ei cauze este frecvent semnalată în patologia pediatrică, începând din perioada neonatală şi până adolescenţă. Prin consecinţele atât cele imediate (convulsii, comă), cât tardive (afectare neurologică), hipoglicemia trebuie cunoscută, prevenită, evitată tratată. Obiective. Prezentarea evoluţiei clinice a unei paciente hipoglicemie severă simptomatică încă de nou-născut. De la naştere, valoarea glicemiei prezintă o dinamică fluctuantă, iar scăderea...
Introducere. Măsurarea indicilor somato-metrici reprezintă o metodă clinică simplă, ce poate fi utilizată pentru evaluarea complicaţiilor cardio-metabolice asociate obezităţii. Obiective. Identificarea obezităţii şi relevanţei utilizării IMC sau a raportului circumferinţă talie-înălţime diagnosticul precoce al acestora, într-un grup de copii adolescenţi obezi. Material metode. Studiul inclus 174 diagnosticaţi cu obezitate primară pe perioadă 3 ani. Variabilele analizate au fost: indicii...
<h3>Background</h3> Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children, that usually manifests as an expanding mass, sometimes located head (parameningeal RMS). RMS treatment involves a combination of surgery, chemotherapy and radiation therapy. Tumours brain and/or hypothalamus may cause insufficiencies hypothalamic-pituitary axis. Also, irradiation directly impair both hypothalamic pituitary function, leading to isolated or associated hormonal defficiencies. Growth...
Abstract Cystic fibrosis related diabetes (CFRD) is a redoubtable complication associated to cystic fibrosis, with an increasing frequency, directly proportional children life expectancy. Although this has similar features DM type 1 and some 2, the evolution even response insulin therapy different. It also possible that other factors influence CFRD clinical expression subsequently disease evolution. Since its 1t diagnosis was more frequent pulmonary exacerbations deterioration of respiratory...