A5080938855- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Supramolecular Chemistry and Complexes
- Synthesis and properties of polymers
- Chemical Synthesis and Analysis
- Nanomaterials for catalytic reactions
- Asymmetric Hydrogenation and Catalysis
- Biofuel production and bioconversion
- Porphyrin and Phthalocyanine Chemistry
- Inorganic and Organometallic Chemistry
- Structural and Chemical Analysis of Organic and Inorganic Compounds
- Advanced MRI Techniques and Applications
- Axial and Atropisomeric Chirality Synthesis
- Polymer Synthesis and Characterization
- Digitalization and Economic Development in Agriculture
- Protist diversity and phylogeny
- Catalysis for Biomass Conversion
- Microbial Natural Products and Biosynthesis
- Economic and Technological Developments in Russia
- Molecular spectroscopy and chirality
- Lanthanide and Transition Metal Complexes
- Polymer Science and PVC
- Synthesis and Reactivity of Sulfur-Containing Compounds
- Silicone and Siloxane Chemistry
- Epoxy Resin Curing Processes
University of Oxford
2024-2025
Kurchatov Institute
2023-2025
University of Basel
2021-2024
Lomonosov Moscow State University
2019-2023
University of Cologne
2022
Moscow State University
2019
Research Institute of Synthetic Fiber with the Pilot Plant
1969-1972
Abstract Cleaner synthesis of amines remains a key challenge in organic chemistry because their prevalence pharmaceuticals, agrochemicals and synthetic building blocks. Here, we report different paradigm for chemoselective hydrogenation nitro compounds to amines, under mild, aqueous conditions. The hydrogenase enzyme releases electrons from H 2 carbon black support which facilitates nitro-group reduction. For 30 nitroarenes demonstrate full conversion (isolated yields 78 – 96%), with...
Molecular capsules enable the conversion of substrates inside a closed cavity, mimicking to some extent enzymatic catalysis. Chirality transfer from molecular capsule onto encapsulated substrate has been only studied in few cases. Here we demonstrate that chirality is possible rather large container approximately 1400 Å
The methylotrophic yeast Komagataella kurtzmanii belongs to the group of homothallic fungi that are able spontaneously change their mating type by inversion chromosomal DNA in MAT locus region. As a result, natural and genetically engineered cultures these yeasts typically contain mixture sexually dimorphic cells prone self-diploidisation spore formation accompanied genetic rearrangements. These characteristics pose significant challenge development stable producers for industrial use. In...
We report a family of lanthanide(III) complexes that act as redox probes via both magnetic resonance and luminescence outputs. The ligands are functionalized with nitro, azobenzene azide groups which reduced to common aniline product, each responds chemical biocatalytic reductive conditions at different cathodic onset potentials. By judicious choice complexed Ln(III), the can be optimized either for use in imaging (Ln = Gd), or highly efficient turn‐on Tb). Tb(III) analogues essentially...
Lanthanide complexes of DOTA monoesters bearing nitrobenzyl and nitroimidazole groups are shown to be converted the corresponding under chemical enzymatic conditions, giving rise favorable changes in luminescence properties europium terbium relaxometric gadolinium complexes. The more rapidly than their benzyl analogues. We propose that activation these may occur by ester cleavage rather nitro reduction fragmentation since a simple group also cleaved same albeit slowly.
We report a new paradigm for chemoselective hydrogenation of nitro compounds to amines, under mild, aqueous conditions. Hydrogenase enzyme releases electrons from H2 carbon black support which facilitates nitro-group reduction. For 30 nitroarenes we demonstrate full conversion (isolated yields 78 – 96%), with products including pharmaceuticals benzocaine, procainamide and mesalazine, 4-aminophenol precursor acetaminophen (paracetamol). also showcase gram-scale synthesis 90% isolated yield....
A supramolecular container enables highly enantioselective iminium chemistry using simple proline as the chiral source.
Diverse calixarene 1,3-diketones including those having additional triazole or crown ether functionalities can be readily prepared by acylation of magnesium enolates acetophenones with calixarene-based 1-acylbenzotriazoles.
Abstract Terpenes, created in Nature via tail‐to‐head terpene (THT) cyclizations, have long fascinated chemists due to their complex structures and biological activities. Recreating such THT cyclizations the laboratory using man‐made catalysts has been challenging. Especially difficult is performing reaction an enantioselective fashion, as substrate flexible does not contain much functionality form strong interactions with chiral catalyst. This study explores cyclization inside hexameric...
2,2′-Bisindole bridges can be easily created at (thia)calixarene cores providing the molecules with multiple functionalities for application in supramolecular chemistry.
Abstract The yeast strain Komagataella kurtzmanii VKPM Y‐727 shows a significant defect in sorbitol utilization compared to closely related K. phaffii (including strains formerly identified as Pichia pastoris ). Our aim was investigate the factors that determine phenotype of wild‐type and obtain with an improved ability utilize sorbitol. We sequenced annotated genome it GS115. Five GS115 genes might be involved metabolism were selected transferred into Y‐727. transfer modified SOR1 gene...
Abstract Molekulare Kapseln ermöglichen die Umwandlung von Substraten innerhalb eines geschlossenen Hohlraumes und ahmen bis zu einem gewissen Grad enzymatische Katalyse nach. Ein Chiralitätstransfer der molekularen Kapsel auf das eingekapselte Substrat wurde nur in wenigen Fällen untersucht. Hier zeigen wir, dass ein relativ großen Behälters etwa 1400 Å 3 möglich ist. Insbesondere präsentieren wir (1) ersten Beispiele optisch aktiver hexamerer Resorcin[4]aren Kapseln, (2) ihre Fähigkeit zur...
The present work focuses on the impact of polymer polarity and hydrogen-bonding (H-bonding) end groups association strength structure dynamics poly(alkyl ether)-based supramolecular model polymers studied by means small angle scattering (SAS), rheology, dielectric relaxation spectroscopy (DRS), differential scanning calorimetry (DSC). These consist poly(propylene oxide) (PPO) or poly(ethylene (PEO) backbone that self-assembly in bulk via hydrogen bonding (H-bonding). Diaminotriazine (DAT)...