A5041366447- Sulfur-Based Synthesis Techniques
- Organoselenium and organotellurium chemistry
- Chemical Synthesis and Reactions
- Organic Chemistry Cycloaddition Reactions
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Synthesis and biological activity
- Multicomponent Synthesis of Heterocycles
- Synthesis and Reactivity of Sulfur-Containing Compounds
- Radical Photochemical Reactions
- Click Chemistry and Applications
- Organophosphorus compounds synthesis
- Catalytic C–H Functionalization Methods
- Catalytic Alkyne Reactions
- Organometallic Compounds Synthesis and Characterization
- Synthesis of Indole Derivatives
- Synthesis of heterocyclic compounds
- Synthesis and Biological Evaluation
- Free Radicals and Antioxidants
- Synthesis and Characterization of Pyrroles
- Asymmetric Synthesis and Catalysis
- Synthesis and Characterization of Heterocyclic Compounds
- Inorganic and Organometallic Chemistry
- Vanadium and Halogenation Chemistry
- Selenium in Biological Systems
Universidade Federal de Pelotas
2016-2025
Universidade Federal de Santa Maria
1995-2022
Center for Effective Philanthropy
2015
Instituto de Ciências Farmacêuticas
2013
Universidade do Estado de Santa Catarina
2013
Universidade Regional do Noroeste do Estado do Rio Grande do Sul
2003
Essential oil (EO) of the leaves Eugenia uniflora L. (Brazilian cherry tree) was evaluated for its antioxidant, antibacterial and antifungal properties. The acute toxicity EO administered by oral route also in mice. exhibited antioxidant activity DPPH, ABTS FRAP assays reduced lipid peroxidation kidney showed antimicrobial against two important pathogenic bacteria, Staphylococcus aureus Listeria monocytogenes, fungi Candida species, C. lipolytica guilliermondii. Acute administration did not...
We describe herein the use of glycerol as solvent in copper-catalyzed cross-coupling reaction diaryl diselenides with arylboronic acids using CuI and DMSO additive. This was performed bearing electron-withdrawing electron-donating groups, affording corresponding selenides good to excellent yields. The glycerol–CuI mixture can be directly reused for further reactions.
Organochalcogen compounds (containing S, Se and Te) are interesting either for use as an intermediate in the synthesis of complex molecules or exploitation their biological properties. The growing number papers on application organochalcogen has been accompanied by a concern about how they prepared. Here, we provide comprehensive updated review recent synthetic methods available using alternative solvents solvent-free conditions non-classical energy sources (microwaves irradiation,...
This review presents the recent advances involving several applications of five-membered cyclic carbonates and derivatives. With more than 150 references, it covers period from 2012 to 2020, with special emphasis on use as building blocks for organic synthesis material elaboration. We demonstrate application in important chemical transformations, such decarboxylation, hydrogenation, transesterification reactions, among others. The presence molecules high biological potential is also...
We present here the results on use of 1-n-butyl-3-methylimidazolium methylselenite, [bmim][SeO2(OCH3)], in synthesis symmetrical disulfides starting from thiols. This efficient and improved method is general for aromatic, aliphatic, functionalized thiols affording good to excellent yields after easy work up. The a microwave accelerates reaction [bmim][SeO2(OCH3)] was reused further oxidation reactions.
We described herein the use of glycerol as solvent in catalyst-free synthesis benzodiazepines and benzimidazoles. This simple efficient method furnishes corresponding 1-H-1,5-benzodiazepines 1,2-disubstituted benzimidazoles good yields by condensation o-phenylenediamine with several ketones aldehydes, respectively. In addition, can be easily re-utilized for further reactions up to four times without lost activity.
Abstract A simple and rapid method for the selective synthesis of 3‐(organylselanyl)‐1 H ‐indoles 3‐(organylselanyl)imidazo[1,2‐ a ]pyridines catalyzed by CuI/SeO 2 under ultrasound irradiation was developed. This protocol employs diverse range 1 or imidazo[1,2‐ diorganyl diselenides to afford corresponding products selectively in good excellent yields. Moreover, antioxidant activity these compounds evaluated using wide vitro assays, such as 2‐azinobis‐3‐ethylbenzothiazoline‐6‐sulfonic acid...
Bis(indolyl)methanes were efficiently synthesized using ammonium niobium oxalate (ANO) as the catalyst and water or glycerol solvent.
Organocatalytic enamine–azide [3 + 2] cycloadditions between β-keto sulfones and aryl azides can be performed at room temperature in good to excellent yields of products the presence catalytic amounts pyrrolidine (5 mol %). The proposed organocatalytic methodology was found applicable arylsulfones containing a range substituents. A wide variety also work. Basically, this constitutes remarkably efficient protocol for synthesis novel 1,2,3-triazole compounds.
Herein, we evaluated the solvent effect on 77 Se NMR chemical shifts of diphenyl diselenides. To gain a deeper insight into shift behavior, DFT calculations have been performed.
Abstract We describe here an efficient and regioselective synthesis of arylselanyl anilines by copper‐catalyzed direct arylselenation arylamines. Using a catalytic amount copper iodide in dimethyl sulfoxide at 110 °C under air atmosphere, range was obtained directly from substituted diaryl diselenides moderate to good yields via CH bond cleavage aryl amines. magnified image
We described herein the use of imidazolium ionic liquids [bmim]PF6 and [bmim]BF4 in selective, metal catalyst-free synthesis unsymmetrical diaryl selenides by electrophilic substitution arylboron reagents with arylselenium halides (Cl Br) at room temperature. This is a general reaction it was performed arylboronic acids or potassium aryltrifluoroborates bearing electron-withdrawing electron-donating groups, affording corresponding good to excellent yields. The liquid [bmim][PF6] easily...
Abstract In the last two decades, search for sustainability in chemical reactions has attached a lot of attention. this focus review, use ultrasound (US) as an alternative energy source organic synthesis is presented. The improvement performance due to cavitation effect been previously studied and described. US guarantees often higher yields than other green methodologies, microwave or ball milling. impressive positive are demonstrated review mainly organometallic multi‐component (MCRs),...
New selenium and tellurium containing chrysin derivatives were synthesized their antioxidant activities evaluated. Butyltelluro-chrysin presented better activities.
We report herein an alternative method for the synthesis of seleno-dibenzocycloheptenones and seleno-spiro[5.5]trienones through radical cyclization biaryl ynones in presence diorganyl diselenides, using Oxone as a green oxidizing agent. The reactions were conducted acetonitrile solvent sealed tube at 100 °C. protocol is operationally simple scalable, exhibits high regioselectivity, allows 24 dibenzocycloheptenones/spiro[5.5]trienones yields up to 99%, 17 which are unpublished compounds....
The new acidic ionic liquid phenyl butyl ethyl selenonium tetrafluoroborate, [pbeSe]BF4, was successful used as a co-catalyst in the Baylis–Hillman reaction of aldehydes and electron-deficient alkenes. adducts were obtained moderated to good yields relatively short times under mild conditions.