A5100643855- Liver Disease and Transplantation
- Nutrition and Health in Aging
- Liver Disease Diagnosis and Treatment
- Diabetes Treatment and Management
- Smoking Behavior and Cessation
- Reconstructive Surgery and Microvascular Techniques
- Aortic aneurysm repair treatments
- Helicobacter pylori-related gastroenterology studies
- Diabetes Management and Research
- Gastrointestinal motility and disorders
- Gastroesophageal reflux and treatments
- Aortic Disease and Treatment Approaches
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Biomedical Ethics and Regulation
- Cardiac Structural Anomalies and Repair
- Regional Development and Environment
- Cancer-related molecular mechanisms research
- Peptidase Inhibition and Analysis
- Peripheral Artery Disease Management
- Trauma and Emergency Care Studies
- Anesthesia and Sedative Agents
- Air Quality and Health Impacts
- Statistical Methods in Clinical Trials
- Neuropeptides and Animal Physiology
- Mycobacterium research and diagnosis
Nanjing Medical University
2021-2024
Union Hospital
2022-2023
Huazhong University of Science and Technology
2021-2023
Union Hospital
2021-2023
State Key Laboratory of Information Engineering in Surveying Mapping and Remote Sensing
2021-2023
University of Wyoming
2022
Jiangsu Province Hospital
2021
Princess Margaret Cancer Centre
2020
University Health Network
2020
Wuhan University of Technology
2019
Background Sarcopenia is frequently found in patients with cirrhosis and associated liver dysfunction, cirrhosis-related complications, poorer quality of life. Purpose To evaluate changes skeletal muscle fat mass at CT to the relationship sarcopenia mortality after transjugular intrahepatic portosystemic shunt (TIPS) placement. Materials Methods Patients who underwent TIPS between August 2016 May 2020 were included this retrospective study. Skeletal evaluated L3 vertebra baseline 2 months, 5...
BACKGROUND:This prospective, randomized, controlled study evaluated the efficacy and safety of remimazolam tosilate sedation with adjuvant sufentanil, relative to propofol, for Chinese patients liver cirrhosis undergoing gastroscopy. MATERIAL AND METHODS:Patients (n=148) aged 18-65 years gastroscopy were randomly equally allocated receive either 0.107 mg/kg (remimazolam group) or 2 propofol. Patients received intravenous sufentanil 0.15 μg/kg before drug. If necessary, an additional dose...
Keverprazan, a novel potassium-competitive acid blocker, was approved for treating acid-related diseases. This study aimed to analyze the safety, pharmacokinetics (PKs) and pharmacodynamics (PDs) of multiple doses keverprazan. randomized, positive-/placebo-controlled, phase Ic trial. Twenty-six healthy adults were randomized receive 20 mg/day keverprazan (n = 8), 40 placebo 6), or vonoprazan 4) 7 days. Safety, PK PD assessments conducted. In keverprazan, vonoprazan, groups, adverse events...
Keverprazan is a novel potassium-competitive acid blocker for the treatment of acid-related diseases. To evaluate safety, pharmacokinetics, pharmacodynamics, and food effect single oral doses keverprazan in healthy Chinese subjects. In dose-escalated phase Ia trial, first 8 subjects received 5 mg, others successively entered 10 20 40 60 mg groups were randomized to receive (n=8), lansoprazole (LSZ) 30 (n=2) or placebo each dose group. The Ib study randomly enrolled fasting-fed (n=7)...
Aims To evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of cetagliptin (CAS number:2243737-33-7) in Chinese patients with type 2 diabetes mellitus (T2DM). A population PK/PD model was developed to quantify PK PD characteristics patients. Materials methods 32 adults T2DM were enrolled this study. The subjects randomly assigned receive either (50 mg or 100 mg), placebo, sitagliptin (100 mg) once daily for 14 days. Blood samples collected analysis. Effects on...
Purpose This study investigated nicotine dependence as an independent risk factor for upper aerodigestive tract (UADT) cancers, including lung and head neck cancers (HNC). The aimed to isolate the direct effect of dependence, tobacco smoking. Methods A case-control with a total 4957 participants was conducted in Ontario, Canada, which 2964 categorized either current or former smokers were used analysis. Nicotine ever-smokers (2360 UADT cases 604 controls) measured using Fagerström Test...
This study investigated the pharmacokinetics and pharmacodynamics properties, safety tolerability of cetagliptin.Forty-eight healthy subjects were enrolled in this study. Three cohorts sequential order: 50, 100 200 mg cetagliptin. Positive control (sitagliptin mg) was designed as open label. Blood samples collected analysed for pharmacokinetic pharmacodynamic properties. Safety assessed throughout study.Following multiple oral doses, cetagliptin rapidly absorbed reached peak plasma...
To evaluate the safety and efficacy of thoracic endovascular aortic repair (TEVAR) for retrograde type A intramural hematoma (IMH) with intimal disruption in descending aorta report our therapeutic experience.From January 2014 to October 2020, a total 24 consecutive patients IMH (intimal tear or ulcer-like projection) underwent TEVAR. The demographics, clinical characteristics, treatment details, imaging information, follow-up results were reviewed.Among all IMH, 13 (54.2%) presented...
Pulmonary Function in Jute Dust‐Exposed Workers: A Dose‐Response Relationship: Jie C hen , et ai. Department of Pneumoconiosis, China Medical University School Preventive Medicine —Pulmonary function tests were carried out on 488 jute‐exposed workers a jute mill and 332 control workers. An industrial hygiene survey was also conducted. Most the exposed to dusts containing less than 6% silica, whereas few approximately 10‐16% silica. The cumulative dose dust exposure [dust level (mg/m 3 ) X...
This paper analyzes the global legislation on river basins, especially Rhine River protection convention in Europe and Tennessee basin authority act United States, evaluates basins by analyzing changes economic environment of basins.The relevant experience foreign watershed is obtained integrating various countries.Based characteristics China's Yangtze belt basin, this discusses legislative model, principles, main contents other parts law.According to legislation, law not only feasible but...
The data on endovascular aortic repair (EVAR) for traumatic dissection (TAD) are lacking. Hence, this study aimed to evaluate the efficacy of EVAR TAD and report our experience based patients from medical center with a relatively long follow-up. A total 25 consecutive underwent October 2015 2020. demographics, imaging characteristics, clinical features, treatment details, follow-up results were reviewed. Urgent was performed in 3 (12%), while remaining 22 (88%) delayed EVAR. Systematic...
Objective To analyze the patients who experienced conservative therapy or surgical operation owing to foreign bodies(FBs) ingestion below pylorus retrospectively, aim summarize different methods including prevention FBs when we confront in ages children. Methods Sixteen (eleven male and five female) were hospitalized for between 2011 June 2014 evaluated retrospectively. Results The mean age was 5.5 years(65.9±61.0). Nine got treatment seven obtained therapy.75% their families...
Objective To report the surgical techniques and clinical results of modified posterior neurocutaneous vascular axial flap in forearm.Methods A reversed forearm pedicled with distal segment interosseous artery was designed to repair skin defects hand caused by hish energy injuries.Tweney-two patients defect dorsal wrist were treated this flap.The distal-most at proximal interphalangeal joint.The largest measured 14 cm×10 cm.The longest pedicle 12 cm.Results All flaps transferred successfully...