A5006036829- Diet and metabolism studies
- Tryptophan and brain disorders
- Pancreatic function and diabetes
- Educational Technology in Learning
- Intensive Care Unit Cognitive Disorders
- Sirtuins and Resveratrol in Medicine
- Childhood Cancer Survivors' Quality of Life
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Adipose Tissue and Metabolism
- E-Learning and Knowledge Management
- Body Composition Measurement Techniques
- Stress Responses and Cortisol
- Exercise and Physiological Responses
- Amino Acid Enzymes and Metabolism
- Cardiovascular and exercise physiology
- Advertising and Communication Studies
- Health, Education, and Physical Culture
- Tissue Engineering and Regenerative Medicine
- Neonatal Health and Biochemistry
- Genetics and Neurodevelopmental Disorders
- Coenzyme Q10 studies and effects
- Fatty Acid Research and Health
- Alzheimer's disease research and treatments
- Calcium signaling and nucleotide metabolism
- Nutritional Studies and Diet
Universitat de València
2019-2024
Centro de Investigación Biomédica en Red
2019-2024
INCLIVA Health Research Institute
2019-2024
Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable
2021
Mice models of Alzheimer's disease (APP/PS1) typically experience cognitive decline with age. G6PD overexpressing mice (G6PD-Tg) exhibit better protection from age-associated functional including improvements in metabolic and muscle functions as well reduced frailty compared to their wild-type counterparts. Importantly G6PD-Tg show diminished accumulation DNA oxidation the brain at different ages both males females. To further explore potential benefits modulating activity neurodegenerative...
Abstract Background Frailty is a major age‐associated syndrome leading to disability. Oxidative damage plays significant role in the promotion of frailty. The cellular antioxidant system relies on reduced nicotinamide adenine dinucleotide phosphate (NADPH) that highly dependent glucose 6‐P dehydrogenase (G6PD). G6PD‐overexpressing mouse (G6PD‐Tg) protected against metabolic stresses. Our aim was examine whether this protection delays Methods Old wild‐type (WT) and G6PD‐Tg mice were evaluated...
Background: Ketogenic dietary therapies (KDT) are used as a treatment in childhood epilepsy. However, their mechanism has not yet been established. The main objective of this study was to determine the changes transcriptomic profile induced by KDT children with epilepsy order shed light on its possible mechanisms. Methods: Eight refractory were enrolled study. Peripheral blood mononuclear cells obtained before and after treated for minimum 6 months. RNA extracted mRNA miRNA profiling...
El proyecto DEBATMITAL tiene como objetivo principal aumentar la participación de los alumnos en sesión práctica sobre “Mitos Alimentación” que forma parte asignatura optativa “Alimentación y Dietética” del grado Medicina Universidad Valencia. Frente a clase magistral, era básicamente herramienta utilizada cursos anteriores, se organiza grupos debate para tratar diversas afirmaciones relacionadas con alimentación pueden escuchar comúnmente. La valoración estudiantes hacen esta iniciativa es...
Como sustitución de la clase magistral, en sesión dedicada a tratar las características “dietas occidentales moda” asignatura optativa 34493-Alimentación y Dietética del Grado Medicina UV, se utilizaron infografías previamente diseñadas por los estudiantes. Con esta iniciativa pretendía mejorar participación alumnado asignatura, además profundizar materia, sus habilidades digitales búsqueda síntesis información. Esta propuesta fue bien valorada el estudiantado, que mostró su preferencia...
Alzheimer's Disease (AD) is a neurodegenerative disorder and the most common type of dementia in elderly. AD characterized by beta-amyloid (Aβ) peptide neurofibrillary tangles accumulation brain, accompanied progressive neuronal dysfunction neurodegeneration. Along with these phenomena, it should be noticed that alterations energy metabolism an increased production free radicals leading to oxidative stress, are also characteristics AD. Against reactive oxygen species (ROS), cellular...