Emergence and spread of carbapenemase-producing Enterobacteriaceae (CPE) are two the major problems currently threatening global public health. In Nigeria, interest in CPE is recent. Sokoto, northwest there no data on prevalence mechanism underlying carbapenem resistance. this study, we aimed to investigate presence clinical carbapenems-resistant isolates leading hospitals Nigeria. A total 292 non-duplicate isolated from specimens processed diagnostic laboratories between January June 2019...

Momordica charantia is a medicinal bitter leaf, which has been in use for ages by our fore fathers, hence the need to investigate its biological activities order elucidate values. The proximate and mineral compositions of M. were determined protein, fibre, phosphorus, calcium, potassium, sodium, manganese, iron, copper zinc contents 25.09, 5.01, 0.45, 1.04, 2.72, 72.6, 1.99, 1.77, 70.7 44.9 mg/100 g, respectively. result further showed that sodium content higher than all other elements...

Antibiotics are becoming ineffective against resistant bacteria. The use of essential oils (EOs) may constitute an alternative solution to fight multidrug-resistant This study aims determine the chemical composition EOs from five populations endemic Algerian Origanum glandulosum Desf. and investigate their potential antibacterial activity uropathogenic E. coli strains. were obtained by hydrodistillation was investigated gas chromatography/mass spectrometry (GC/MS). evaluated disc diffusion...

Abstract Background: In spite of its global notoriety and WHO alarm, Acinetobacter baumannii is still an understudied critical-priority pathobiont in Nigeria. We characterized antimicrobial susceptibility profile resistance genes during outbreak. Materials Methods: This cross-sectional study involved collection patients’ urine samples swabs from unit staff’s hands ward environments for the identification A . strains using standard morphologic biochemical methods. The disk diffusion method...

Surgical site infection (SSI) is one of the most frequent complications surgical interventions. Several factors have been identified as major determinants occurrence SSIs. The present study determined and possible risk associated with SSIs at a tertiary healthcare facility in Abuja, Nigeria. All patients scheduled for operation hospital during period who consented to participate willingly were observed prospectively SSI based on criteria stipulated by United States Centre Disease Control...

Carbapenems are among the antibiotics of last resort against infections caused by antibiotic resistant bacteria. However, resistance to this important class is on increase due expression metallo-betalactamases (MBLs). This study investigated occurrence MBL-producing bacteria in a healthcare facility Sokoto, Nigeria. Swabs were collected from rectum (n = 29) and bed linens 27) patients within surgical wards hospital between March August, 2018 processed using Centers for Disease Control...

<ns3:p><ns3:bold>Background</ns3:bold>: Colistin resistance is a major breach in our last line of defense and without urgent action, we are heading for post-antibiotic era, which common infections minor injuries can once again kill. To the best knowledge, use bibliometric analytical technique examining colistin resistance-related research does not exist literature.</ns3:p><ns3:p> <ns3:bold>Methods</ns3:bold>: Here, analyze present indicators global literature research. The Scopus database...

Surgical antimicrobial prophylaxis (SAP) prevents incision site infection. We assessed SAP compliance with existing international guidelines, evaluated the appropriateness of doses, and determined risk factors for under-dosing. A retrospective chart review was performed patients who under-went surgery administered prophylaxis. Compliance guidelines evaluated. Antimicrobial doses were categorized as under-, normal-, or over-dose. Of 303 surgical patients, 97.7% received complete achieved in...

There is limited data on the prevalence and antibiotic susceptibility profile of Gram-negative bacteria in northwest Nigeria. This study thus aimed to investigate multidrug resistant bacterial infections among patients two healthcare facilities Sokoto, Nigeria.A total 735 non-duplicate clinical isolates were collected between January July 2019, from specimens processed by diagnostic microbiological laboratory hospitals. The identified using MALDI-TOF mass spectrometry tested against a panel...

Empedobacter falsenii is an emerging opportunistic pathogen that has been occasionally implicated in various human infections. In this study, we described the genomic features of a multidrug resistant E. Q1655 obtained from patient attending public hospital Sokoto, northwest Nigeria. The isolate, Q1655, was isolated stool sample identity isolate confirmed by MALDITOF-MS. disc diffusion test and modified Carba-NP were used for phenotypic antibiotic susceptibility carbapenemase enzyme...

Background: Globally, contamination of banknotes with various microbial species is increasingly being reported. This usually results from improper handling during exchange goods and services. In the present study, we aimed to determine load, prevalence presence Extended Spectrum Beta Lactamase (ESBL) among bacteria isolated Nigerian Naira notes circulating in Bauchi metropolis.Methodology: A total 400 denominations were randomly collected aseptically, cultured viable counts determined. The...

Objective: The hospital environment is a major source of&#x0D; nosocomial pathogens. These pathogens could contaminate and colonize surgical&#x0D; wounds leading to infections. This study evaluated the bacteriological quality&#x0D; of air floors surgical wards University Teaching Hospital in Abuja,&#x0D; Nigeria.&#x0D; &#x0D; Methods: Bacteriological&#x0D; quality floor was using&#x0D; passive sampling swabbing methods respectively. isolates were&#x0D; characterized using rapid test kits...

This study aimed to determine the incidence and molecular mechanisms of carbapenem-resistant Enterobacteriaceae in patients from Sétif University Hospital, Algeria. Nonduplicate clinical bacterial isolates recovered attending Hospital were collected between April October 2018. Species identification was performed by MALDI-TOF/MS (matrix-assisted laser desorption ionization-time flight mass spectrometry) method. The susceptibility carbapenems determined using disc diffusion carbapenem...

The increasing resistance of most microorganisms to existing armamentarium antibiotics has made the search for new antimicrobial agents particularly from natural products more imperative. This study was aimed at evaluating activity chloroform, ethyl acetate, n-hexane and n-butanol fractions Vernonia glaberrima against some selected human pathogens with a view identify active fraction plant ascertain veracity use in ethno-medicinal practice. V. eight bacterial pathogens- Methicillin resistant...