- Connective tissue disorders research
- Shoulder Injury and Treatment
- Dermatological and Skeletal Disorders
- Dupuytren's Contracture and Treatments
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Shoulder and Clavicle Injuries
- Cardiovascular Syncope and Autonomic Disorders
- Bone health and treatments
- Hip disorders and treatments
- Heart Rate Variability and Autonomic Control
- Pain Mechanisms and Treatments
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Musculoskeletal pain and rehabilitation
- Sports injuries and prevention
- Tendon Structure and Treatment
- Medical research and treatments
- Neurogenetic and Muscular Disorders Research
- Bone fractures and treatments
- Myofascial pain diagnosis and treatment
- Parkinson's Disease and Spinal Disorders
- Cardiovascular and exercise physiology
- High Altitude and Hypoxia
- Ubiquitin and proteasome pathways
- Injury Epidemiology and Prevention
- Health and Well-being Studies
Ghent University Hospital
2015-2024
Ghent University
2013-2023
Duke University
2017
Great Ormond Street Hospital
2017
University College London
2017
Hospital of St John & St Elizabeth
2017
University of Amsterdam
2017
Amsterdam University of Applied Sciences
2017
University of Southern Denmark
2017
Macquarie University
2017
New insights into the phenotype of Joint Hypermobility Syndrome (JHS) and Ehlers‐Danlos Syndrome‐hypermobile type (hEDS) have raised many issues in relation to classification, diagnosis, assessment, treatment. Within multidisciplinary team, physical therapy plays a central role management individuals with hypermobility related disorders. However, therapists are not familiar diagnostic criteria, prevalence, common clinical presentation, management. This guideline aims provide practitioners...
Abstract Objective To investigate lower extremity muscle mass, strength, functional performance, and physical impairment in women with the Ehlers‐Danlos syndrome hypermobility type (EDS‐HT). Methods Forty‐three EDS‐HT 43 sex‐ age‐matched healthy control subjects participated. Muscle mass was determined by dual x‐ray absorptiometry. strength endurance were measured isokinetic dynamometry at angular velocities of 60, 180, 240°/second. Static during posture maintenance also assessed. Pain...
To investigate balance, gait, falls, and fear of falling in patients with the hypermobility type Ehlers-Danlos syndrome (EDS-HT).Twenty-two women EDS-HT 22 sex- age-matched healthy control subjects participated study. Each subject performed modified Clinical Test Sensory Interaction on Balance (mCTSIB) Tandem Stance test (TS) an AccuGait force platform to assess balance by center pressure-based postural sway measures. The GAITRite walkway system was used record spatial-temporal gait...
The purpose of this study was to investigate functional impairment and the impact pain in patients with Ehlers-Danlos syndrome, hypermobility type (EDS-HT), compare burden disease that women fibromyalgia (FM) rheumatoid arthritis (RA).A total 206 female were compared (72 EDS-HT, 69 FM, 65 RA). Functional assessed Sickness Impact Profile (SIP), psychosocial chronic quantified Multidimensional Pain Inventory (MPI). Data on symptoms collected.SIP results showed clinically relevant...
Objective: In this study we evaluated the effect of sprint interval training on metabolic and physical fitness in adolescents young adults with intellectual disabilities when compared continuous aerobic no (control). Methods: Fifty-four persons (age: 17 (3.0), body mass index: 27.7 (3.7), intelligence quotient: 59 (8.6)) were matched based age, gender quotient between ( n = 17), 15) control 14). Sprint was composed three blocks 10 minutes at ventilatory threshold (blocks 1 3: bouts 15...
Objective. To investigate whether orthostatic intolerance (OI) is a significant predictor for fatigue in Ehlers-Danlos Syndrome, hypermobility type (EDS-HT). Methods. Eighty patients with EDS-HT and 52 controls participated the first part of study, which consisted questionnaires. Fatigue was evaluated using Checklist Individual Strength (CIS). As possible determinants OI [Autonomic Symptom Profile (ASP)], habitual physical activity (Baecke), affective distress [Hospital Anxiety Depression...
Abstract Objective To investigate the passive properties of plantar flexors muscle–tendon tissue in patients with hypermobility type Ehlers‐Danlos syndrome (EDS‐HT). Methods Twenty‐five women EDS‐HT and 25 sex‐ age‐matched healthy control subjects participated study. Passive resistive torque (PRT) was measured an isokinetic dynamometer during 2 standardized stretch protocols to obtain muscle tension. Protocol 1 consisted 4 continuous cycles a predetermined angle 10° dorsiflexion. slow onset...
Purpose: The patients diagnosed with Ehlers–Danlos Syndrome Hypermobility Type (EDS-HT) are characterized by pain, proprioceptive inacuity, muscle weakness, potentially leading to activity limitations. In EDS-HT, a direct relationship between strength, proprioception and limitations has never been studied. objective of the study was establish association strength impact on this in EDS-HT patients.Methods: Twenty-four were compared 24 controls. Activity quantified Health Assessment...
The Ehlers–Danlos syndromes (EDSs) are a clinically and molecularly diverse group of heritable connective tissue disorders caused by defects in wide range genes. Recently, bi-allelic loss-of-function mutations the adipocyte enhancer-binding protein 1 (AEBP1) gene were reported three families with an autosomal recessive EDS-like condition characterized thin hyperextensible skin, poor wound healing prominent atrophic scarring, joint hypermobility osteoporosis. Using whole exome sequencing, we...
The multisystemic comorbid symptoms/conditions of hypermobility spectrum disorders (HSD) and hypermobile Ehlers-Danlos syndrome (hEDS) often significantly affect daily life. Many these symptoms are under-recognised during diagnosis treatment, therefore a comprehensive questionnaire was developed to evaluate their presence impact. Spider's eight domains assess neuromusculoskeletal, pain, fatigue, cardiac dysautonomia, urogenital, gastrointestinal, anxiety, depression symptoms. This paper aims...