A5002913124- Connective tissue disorders research
- Hip disorders and treatments
- Shoulder Injury and Treatment
- Cardiovascular Syncope and Autonomic Disorders
- Cardiovascular Function and Risk Factors
- Bone health and treatments
- Parkinson's Disease and Spinal Disorders
- Botulinum Toxin and Related Neurological Disorders
- Cardiovascular Issues in Pregnancy
- Heart Rate Variability and Autonomic Control
- Vaccine Coverage and Hesitancy
- Neurogenetic and Muscular Disorders Research
- Musculoskeletal pain and rehabilitation
- Myofascial pain diagnosis and treatment
- Cerebral Palsy and Movement Disorders
- Foot and Ankle Surgery
- Cardiac Arrhythmias and Treatments
- Aortic Disease and Treatment Approaches
- Orthopedic Surgery and Rehabilitation
- Bone health and osteoporosis research
- Misinformation and Its Impacts
- Diabetic Foot Ulcer Assessment and Management
- Cardiomyopathy and Myosin Studies
- Sports injuries and prevention
- SARS-CoV-2 and COVID-19 Research
University College London
2016-2025
University College Hospital
2024
Great Ormond Street Hospital
2017-2024
South African Medical Research Council
2022
The Wellington Hospital
2021
Great Ormond Street Hospital for Children NHS Foundation Trust
2019
English Institute of Sport
2018
Hospital of St John & St Elizabeth
2008-2017
Ghent University Hospital
2015-2017
University of Amsterdam
2017
New insights into the phenotype of Joint Hypermobility Syndrome (JHS) and Ehlers‐Danlos Syndrome‐hypermobile type (hEDS) have raised many issues in relation to classification, diagnosis, assessment, treatment. Within multidisciplinary team, physical therapy plays a central role management individuals with hypermobility related disorders. However, therapists are not familiar diagnostic criteria, prevalence, common clinical presentation, management. This guideline aims provide practitioners...
South Africa launched a mass COVID-19 vaccination campaign in May 2021, targeting 40 million adults. Understanding predictors of vaccine intentions was required to achieve this goal. We conducted population-based survey June-July 2021 using the WHO Behavioral and Social Drivers (BeSD) Vaccination tool determine hesitancy, defined as intention refuse or uncertainty whether accept vaccination. There were 1193 participants, mean age 39 (standard deviation 15) years, 53% women, whom 58% trusted...
Musculoskeletal problems are common reasons for seeking primary health care. It has been suggested that many people with 'everyday' non-inflammatory musculoskeletal may have undiagnosed joint hypermobility syndrome (JHS), a complex multi-systemic condition. JHS is characterized by laxity, pain, fatigue and wide range of other symptoms. Physiotherapy usually the preferred treatment option JHS, although diagnosis can be difficult. The lived experience those requires investigation. aim study...
Experts in symptomatic generalized joint hypermobility (S-GJH) agree that upper cervical instability (UCI) needs to be better recognized S-GJH, which commonly presents the clinic as spectrum disorder and hypermobile Ehlers-Danlos syndrome. While mild UCI may common, it can still impactful; though considerably less severe potentially debilitating. includes both atlanto-occipital atlantoaxial instability. In absence of research or published literature describing validated tests prediction...
The aim of the study was to assess feasibility conducting a definitive multicentre randomised controlled trial (RCT) testing an online exercise rehabilitation and behavioural/motivational support intervention for people with postural tachycardia syndrome (PoTS). Feasibility RCT. Two secondary care centres. Adults aged 18 60 years PoTS. Exclusions were serious mental health/cognitive problem preventing safe participation; currently undertaking physical activity equivalent Chief Medical...
Background Conservative management of developmental dysplasia the hip (DDH) in infants under 6-months-old has been well-documented existing literature worldwide, with high success and low complication rates reported globally. Physiotherapy-led DDH clinics have increased UK, yet no formal analysis conducted. This study aimed to assess outcomes UK-based physiotherapy-led comparison medically-led described literature. Method A multi-centre service evaluation four ‘one-stop' included treated for...
Purpose: To explore exercise beliefs and behaviours of individuals with Joint Hypermobility syndrome/Ehlers–Danlos syndrome – hypermobility type to patient experiences physiotherapy.Methods: A cross sectional questionnaire survey design was used collect quantitative qualitative data from adult members the Syndromes Association Ehlers–Danlos Syndrome Support UK. Descriptive inferential statistics were analyse data. Qualitative analysed thematically.Results: 946 questionnaires returned...
BACKGROUND: Generalised joint hypermobility (GJH) is common in the general population and may not confer any adverse symptoms. Joint Hypermobility Syndrome (JHS) a connective tissue disorder that often runs families present with compl
The multisystemic comorbid symptoms/conditions of hypermobility spectrum disorders (HSD) and hypermobile Ehlers-Danlos syndrome (hEDS) often significantly affect daily life. Many these symptoms are under-recognised during diagnosis treatment, therefore a comprehensive questionnaire was developed to evaluate their presence impact. Spider's eight domains assess neuromusculoskeletal, pain, fatigue, cardiac dysautonomia, urogenital, gastrointestinal, anxiety, depression symptoms. This paper aims...
Joint hypermobility syndrome (JHS) is an inherited disorder of connective tissue. It presents as a condition in which there are neuromusculoskeletal signs and symptoms, including pain, without the inflammatory component joint disease such rheumatoid arthritis. Re-attendance rheumatology clinics, re-injury prolonged rehabilitation also features JHS. The primary aims this study were to establish prevalence JHS those attending physiotherapy clinics with disorders Oman.A cross-sectional case...
It has been shown that bone mineral density (BMD) may be lower in patients with haemophilia (PWH). A comparison to control subjects is required thoroughly assess current BMD PWH the UK. The objective of this study was test hypothesis than controls, and more severely affected joints or activity levels. In case-control study, 37 severe were recruited from two centres group age, gender ethnicity-matched participants recruited. All had a scan, musculoskeletal assessment, blood for vitamin D...
Abstract Hypermobility spectrum disorder (HSD) and hypermobile Ehlers-Danlos syndrome (hEDS) can cause widespread or chronic pain, fatigue, proprioceptive coordination deficits resulting in functional restrictions. These conditions are common often unrecognized, patients likely to present physical therapy for musculoskeletal injuries, deficits. Although is considered central managing these conditions, many report pain iatrogenic injuries due inappropriate interventions. The diagnostic...
Abstract Background Idiopathic toe walking (ITW) is an exclusionary diagnosis resulting in a child on the balls of their feet. Preferred treatment options may be due to severity or health professional preference There are limited guidelines supporting consistent recommendations for this condition. This research aimed understand agreement between professionals' knowledge evidence common strategies ITW and if professionals supported these being used clinical practice. Methods An international...
Background It is commonly accepted that dancers are undoubtedly athletes, with ballet perhaps the most demanding dance form. No previous study has sought to define physical attributes desired for classical by professional companies and vocational schools. These likely include both aesthetic features reduce risk of injury as well enhance performance. Method An initial survey question using modified Delphi technique was sent Opinio Survey Software a selected international expert panel. This...
Physiotherapy plays a fundamental role in managing adults with the joint hypermobility syndrome/Ehlers–Danlos syndrome type (JHS/EDS‐HT). However, it is challenge for both patient and physiotherapist as condition poorly understood treatment JHS/EDS‐HT currently undefined. Insight into current practice is, therefore, necessary order to establish baseline knowledge this area long term improve standard of care. Therefore, purpose study was evaluate physiotherapists' gain insight physiotherapy...