A5032609920- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Crystallography and molecular interactions
- Crystal structures of chemical compounds
- Metal complexes synthesis and properties
- Organometallic Compounds Synthesis and Characterization
- Chemical Thermodynamics and Molecular Structure
- Synthesis and Characterization of Heterocyclic Compounds
- Metal-Organic Frameworks: Synthesis and Applications
- Organic and Molecular Conductors Research
- Lanthanide and Transition Metal Complexes
- Magnetism in coordination complexes
- Computational Drug Discovery Methods
- Synthesis and Reactions of Organic Compounds
- Thermal and Kinetic Analysis
- Analytical Chemistry and Chromatography
- Silicone and Siloxane Chemistry
- Protein Structure and Dynamics
- Inorganic Fluorides and Related Compounds
- Radiopharmaceutical Chemistry and Applications
- Synthesis and Biological Evaluation
- Various Chemistry Research Topics
- Chemical Synthesis and Analysis
- Protein Interaction Studies and Fluorescence Analysis
- Chromatography in Natural Products
Adam Mickiewicz University in Poznań
2016-2024
Poznań University of Technology
2018
Synthesis, characterization, crystal structure determination, antiproliferative and antimicrobial studies of five bismuth( iii ) halide complexes with 2-acetylthiophene thiosemicarbazones are presented herein.
Abstract New bismuth(III) bromine compounds of the heterocyclic thioamides were prepared and structurally characterized. The reaction with bromide resulted in formation {[BiBr 2 (μ -Br)(MMI) ] ·CH 3 COCH ·H O} ( 1 ), (MBZIM) 4 ]·Br·2H -Br)(tHPMT) CN} -Br)(PYT) ) -Br)(MBZT) 2CH OH} 5 complexes (MMI: 2-mercapto-1-methylimidazole, MBZIM: 2-mercaptobenzimidazole, tHPMT: 2-mercapto-3,4,5,6-tetrahydro-pyrimidine, PYT: 2-mercaptopyridine MBZT: 2-mercaptobenzothiazole). 1–5 characterized by melting...
The antiproliferative and antibacterial activities of thiosemicarbazones increase markedly with the presence metal ions. One factors determining activity thiosemicarbazone complexes is coordination structure. In this study, biological effects new antimony (III) bismuth different binding modes geometrical structures were demonstrated. Three complexes, formulae {[SbCl3(µ2-S-Hacptsc)(η1-S-Hacptsc)], 2/3H2O,1/3CH2Cl2}, {[SbCl3(κ2-S,N-Hacpmtsc)(η1-S-Hacpmtsc)2CH2Cl2]},...
This paper outlines an unexpected type of intramolecular transformation DDSQ during hydrolytic condensation and surprising catalytic reactivity in silylative coupling.
The high-resolution X-ray data for two bioactive molecules: cytisine (1) and its N-methyl derivative (2) have been collected up to sinθ/λ = 1.12 Å−1 1 1.0 2. This was used modeling of the fine features electron density distribution, including bonding lone pairs. quality model checked by, e.g., rigid bond test RDA analysis. topological analysis (gradient field analysis) has also performed both inter- intramolecular interactions. In case a number intermolecular interactions, from relatively...
Two isostructural (in room temperature) complexes of Bi(III) with halogens and sulfur ligands have been investigated in terms the solid-to-solid phase transitions indicated by temperature. Both chloride bromide (X) general formula (µ2-X)-(BiX2L2)2 exhibit some between 100 333 K, which, apart from numerous similarities, show significant differences, which noted analyzed detail this paper using different techniques, i.e., powder single crystal diffraction or DSC. The obtained results also...
Two new organotin compounds, triphenyl-4,6-diamine-pyrimidine-2-thione-tin(IV) (1) and triphenyl-imidazoline-2-thione-chloro-tin(IV) (2), have been synthesized, spectroscopically structurally characterized, their cytotoxic activities tested against certain cancer cell lines. Atoms-In-Molecules approach has applied for the description of coordination geometry. Both complexes are active chemotherapy-resistant SK-LMS-1 Leiomyiosarcoma cells (IC50 0.1 μM), this activity is 3–4 times larger than...
The reasons behind the formation of S···S contacts in thioamides, most important compounds with terminal sulfur atoms, were investigated by means experimental charge density studies and theoretical calculations. As this interaction is to some extent similar much better-known halogen bond, geometrical analysis was performed using previously determined bond criteria. To investigate representative three compounds, namely, 6-amintothiouracil hydrate (ATU·H2O, 1), 2-imidazolidinethione (IMT, 2),...
Thirty-one examples of crystal structures containing discrete tetraiodide I<sub>4</sub><sup>2−</sup>dianions were identified from the Cambridge Structural Database (CSD) and analyzed in detail order to find factors influencing geometry this rare fragment. The intermolecular interactions are at least partially responsible for changes dianion.
Metal nodes in extend 1D and 3D structures with N,N′-donor linker: the co-ligands decides!
Crystal and molecular structures of new triorganotin complexes have been determined via X-ray diffraction. These include, among others, the second polymorph Ph3Sn(thiocytosine), double complex salt Ph3Sn(methimazole)2·Ph3SnCl2, five-coordinated triphenyltin chloride with methimazole, tetrahydopyrimidine-2-thione, dimethylformamide, dimethyl sulfoxide. Hirshfeld surface analysis allowed for better visualization precise pinpointing differences between polymorphs as well easier intermolecular...
New bismuth (III) complexes with acetophenone-4-methyl-3-thiosemicarbazone (L) and halogens (Cl Br) in both bridging terminal positions have been synthesized structurally characterized using single-crystal X-ray diffraction. The pure or were found to be highly isostructural, which motivated our attempts create solid solutions of these complexes. A series such compounds was prepared various procedures stoichiometries. method for determining the mutual concentrations different halogens, based...
ABSTRACT In this study, we report the synthesis, characterization, and biological investigation of antimony(III) halide complexes with various coordination architectures constructed from thiophene thiosemicarbazones. Antimony(III) thiophene‐2‐carbaldehyde thiosemicarbazone ( 1 , 2 4 5 ) exhibit a square pyramidal geometry, ligands coordinated to central antimony atom in two distinct binding modes. contrast, 2‐acetylthiophene 3 6 7 adopt seesaw geometry. These – represent first reported...
This study explores the formation and properties of new complexes involving gallium(III) thiouracil derivatives-2-thiouracil (TU), 6-methyl-2-thiouracil (MTU), 6-propyl-2-thiouracil (PTU), 5-carboxy-2-thiouracil (CTU), 6-methoxymethyl-2-thiouracil (MMTU). Conducted in aqueous solutions at relatively low concentrations, this research enabled soluble complexes, identified described here for first time. The influence metal-to-ligand ratios on species distribution their fluorescence was examined...