A5004051689- Mosquito-borne diseases and control
- Dengue and Mosquito Control Research
- Malaria Research and Control
- Insect symbiosis and bacterial influences
- Insect Pest Control Strategies
- Insect and Pesticide Research
- Forecasting Techniques and Applications
- Viral Infections and Vectors
- COVID-19 epidemiological studies
- Data-Driven Disease Surveillance
Ministry of Health
2018-2023
Government of Malaysia
2020
Institute for Medical Research
2019
Dengue has enormous health impacts globally. A novel approach to decrease dengue incidence involves the introduction of Wolbachia endosymbionts that block virus transmission into populations primary vector mosquito, Aedes aegypti. The wMel strain previously been trialed in open releases Ae. aegypti; however, wAlbB shown maintain higher density than at high larval rearing temperatures. Releases aegypti mosquitoes carrying were carried out 6 diverse sites greater Kuala Lumpur, Malaysia, with...
Partial replacement of resident Aedes aegypti mosquitoes with introduced carrying certain strains inherited Wolbachia symbionts can result in transmission blocking dengue and other viruses public health importance. J o u r n a l P e -p fWolbachia strain wAlbB is an effective blocker stable at high temperatures, making it particularly suitable for hot tropical climates.Following trial field releases Malaysia, using Ae. have become operationalized by the Malaysian authorities.We report here on...
A large scale study was conducted to elucidate the true relationship among entomological, epidemiological and environmental factors that contributed dengue outbreak in Malaysia. Two areas (Selayang Bandar Baru Bangi) were selected this based on five consecutive years of high cases. Entomological data collected using ovitraps where number larvae used reflect Aedes mosquito population size; followed by RT-PCR screening detect serotype virus mosquitoes. Notified cases, date disease onset, type...
In Malaysia, dengue remains a top priority disease and usage of insecticides is the main method for vector control. Limited baseline insecticide resistance data in hotspots has prompted us to conduct this study. The present study reports use map on susceptibility status Aedes aegypti albopictus provide quick visualization overview distribution resistance.The populations collected from 24 hotspot areas period December 2018 until June 2019 was proactively monitored using World Health...
Dengue is endemic in Malaysia, and vector control strategies are vital to reduce dengue transmission. The Wolbachia strain wAlbB carried by both sexes of Ae. aegypti was released Mentari Court, a high-rise residential site, October 2017 stopped after 20 weeks. frequencies still being monitored at multiple traps across this providing an opportunity examine the spatiotemporal distribution mosquito density with respect year, block, floor, using spatial interpolation ArcGIS, GLMs, contingency...
Dengue is placing huge burdens on the Malaysian healthcare system as well economy. With expansion in number of high-rise residential buildings, particularly urban centers, flight range and behavior Aedes mosquitoes may be altered this habitat type. In study, we aimed to expand understanding vertical distribution dispersal nine selected residences Kuala Lumpur, Selangor, Johor using ovitraps sampling method. We discovered that Ae. aegypti predominant species all study sites. Both albopictus...
Abstract Currently, dengue control relies largely on reactive vector programmes. Proactive vector-control using a rational, well-balanced integrated management approach may prove more successful for control. As part of the development cluster randomized controlled epidemiological trial, study was conducted in Johor Bahru, Malaysia. The included one site (three buildings) and three intervention sites which were treated as follows: targeted outdoor residual spraying only (TORS site, two...
The incidence of dengue in Malaysia has shown an increasing trend since the year 2000. Vector control is primary approach for Malaysia. There urgent need new or modified approaches such as residual spraying on outer walls that can potentially last long enough to Aedes population, particularly outbreak-prone areas. In this field study, we conducted outdoor (ORS) using a newly formulated polymer-enhanced suspension concentrate (SC-PE) deltamethrin. objectives study were evaluate efficacy ORS...
Malaysia Mosquito Autocidal Trap (MyMAT) is a green technology Aedes mosquito trap that does not use harmful chemical substances. This study aimed to evaluate the efficiency of MyMAT in reducing dengue cases and relating rainfall. An experimental field was conducted for 42 weeks at Pangsapuri Nilam Sari, Shah Alam, Selangor. A total 624 allocated four blocks: inside each apartment outside corridors level. rainfall data were collected weekly using mobile rain gauge, respectively. The...
Abstract In Aedes aegypti mosquitoes, introduction of certain strains inherited Wolbachia symbionts results in transmission blocking various viruses public health importance, including dengue. This has resulted a ‘replacement’ strategy for dengue control involving release male and female whereupon is able to spread through Ae. populations high frequency reduces the incidence strain w AlbB an effective blocker stable at temperatures, making it very suitable use hot tropical climates....
Abstract This is the first study to evaluate efficacy of an autodissemination approach, as suggested by WHO. Therefore, approach in small-scale field trials against wild Aedes sp. population was evaluated urbanized setting, Malaysia. Lethal ovitraps enhanced with pyriproxyfen were used control populations at treatment sites, activity assessed using WHO larval bioassays. effectively reduced population. All stations shown be visited mosquitoes 100% complete inhibition eggs and larvae...