A5037925974- Anesthesia and Pain Management
- Cardiac, Anesthesia and Surgical Outcomes
- Anesthesia and Sedative Agents
- Thermal Regulation in Medicine
- Hemodynamic Monitoring and Therapy
- Anesthesia and Neurotoxicity Research
- Cholinesterase and Neurodegenerative Diseases
- Spine and Intervertebral Disc Pathology
- Nausea and vomiting management
- Intensive Care Unit Cognitive Disorders
- Cardiovascular Issues in Pregnancy
- Nicotinic Acetylcholine Receptors Study
- Neurosurgical Procedures and Complications
- Pain Management and Opioid Use
- Intraocular Surgery and Lenses
- Cardiovascular and exercise physiology
- Vagus Nerve Stimulation Research
- Medical History and Innovations
- Traumatic Brain Injury and Neurovascular Disturbances
- Surgical Simulation and Training
- Chemotherapy-related skin toxicity
- Eicosanoids and Hypertension Pharmacology
- Glaucoma and retinal disorders
- Medical and Biological Ozone Research
- Body Contouring and Surgery
University of Alberta
2025
Azienda Ospedaliera Sant'Andrea
2003-2019
Sapienza University of Rome
1984-2019
Instituto do Câncer do Estado de São Paulo
2019
Universidade de São Paulo
2019
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2016-2018
Institut d'Investigacions Biomèdiques de Barcelona
2016-2018
Biogipuzkoa Health Research Institute
2017
Azienda Sanitaria Locale Roma 3
2005
Policlinico Umberto I
1996-2000
Background: New ways of decreasing post‐operative analgesic drug requirements are special interest after major surgery. Magnesium sulfate (MgSO 4 ) alters pain processing and reduces the induction maintenance central sensitization by blocking N ‐methyl‐ d ‐aspartate (NMDA) receptor in spinal cord. We investigated whether supplementation anesthesia with combined intrathecally epidurally infused MgSO reduced patients’ analgesia requirements. Methods: In a randomized, prospective, double‐blind,...
Postoperative shivering may be prevented by maintaining normothermia intraoperatively or it treated using specific drugs. The aim of this study was to compare the efficacy nefopam hydrochloride (nefopam) that clonidine and meperidine in patients undergoing elective neurosurgical procedures. Three groups were included study. Patients group A (60) received i.v., at random, 20 mg nefopam, 50 150 μg immediate postoperative period. incidence time which ceased noted, along with central temperature...
Abstract Background Psychological trauma and adversity are known risk factors for developing suicidal ideation (SI), a marker of severe stress or psychological burden (Winkler et al. 2021). Unfortunately, established interventions SI have limitations, often suboptimally effective, resource-intensive, suffer from high attrition (D’ Anci 2019; Steyn, Koen Jarvis 2022). Eye Movement Desensitization Reprocessing (EMDR) psychotherapy, initially designed to treat Posttraumatic Stress Disorder...
This study was designed to evaluate early postoperative cognitive recovery after total intravenous anaesthesia with remifentanil-propofol or sufentanil-propofol in patients undergoing craniotomy for supratentorial expanding lesions.Sixty were consecutively enrolled, and randomly assigned one of two groups: anaesthesia. To function the Short Orientation Memory Concentration Test (SOMCT) Rancho Los Amigos Scale (RLAS) administered all a double-blind procedure before surgery at 15, 45 min 3 h...
Although anaesthetics are known to alter microcirculation no study has, our knowledge, documented changes in human skeletal microcirculatory function during general anaesthesia.Forty-four patients undergoing maxillofacial surgery at a university hospital were prospectively randomized receive anaesthesia with remifentanil combined propofol or sevoflurane. Muscle was investigated near-infrared spectroscopy (NIRS) before induced and 30 min later. An NIRS device (NIMO, Nirox) used quantify calf...
HYPERTROPHIC cardiomyopathy (HCM) is a genetically transmitted cardiac disease with broad clinical and morphologic spectrum that now recognized increasing frequency. 1 Although the dynamic characteristics of this are influenced by ventricular volume vascular resistance, 2 pregnancy delivery usually well tolerated in patients HCM, only sporadic cases maternal mortality have been reported. 3-5 In most cases, HCM had undergone vaginal safely; however, cesarean section may be carried out for or...
To prospectively assess the impact of intrapleural intercostal nerve block (IINB) associated with mini-thoracotomy on postoperative pain and surgical outcome after major lung resections.Between January 2004 February 2005, we randomly assigned 120 consecutive patients undergoing (10-13 cm) for resections, to receive or not IINB from 4th 8th space at moment thoracotomy using 20 ml (7.5 mg/ml) ropivacain injection dose 4 each space. Postoperative analgesia consisted continuous intravenous...
The aim of our study was to compare three different anesthesiological techniques with regard hemodynamics, recovery, and postoperative morbidity, for craniofacial surgery. One hundred twenty patients American Society Anesthesiologists (ASA) classification I or II patients, 18 32 years old, undergoing maxillary mandibular osteotomies were randomly assigned receive anesthesia propofol-remifentanil (group P), desflurane-remifentanil D), sevoflurane-remifentanil S). All given premedication:...
Summary We report two cases of postoperative iatrogenic tetraparesis, which occurred in different hospitals after surgery for parathyroidectomy. Both patients were on long‐term haemodialysis. The prolonged neck extension usually required by this procedure was probably the main factor involved genesis spinal cord injury. Spinal abnormalities associated with chronic renal failure may have made these more vulnerable. In our opinion, it is advisable to investigate thoroughly any sign stenosis...
Background: Evidence indicating that single‐ and double‐injection techniques for inducing a sciatic nerve block via posterior subgluteal approach yield similar success rate prompted us to investigate whether the two anesthetic lateral approach. We also hypothesized that, owing peculiar anatomic features of at popliteal level, single injection might induce effective anesthesia by targeting tibial only. Methods: Ninety‐six patients undergoing foot surgery were randomized receive 30‐ml...
Background: The key concept underlying the dynamic indexes of preload dependence is physiological heart–lung interaction. During sternotomy this interaction undergoes various changes, some which remain unclear. Our primary aim was to investigate how changes during by evaluating pulse pressure variations (PPV) with chest closed and after in patients ventilated using pressure‐controlled mode. Methods: We prospectively studied 25 undergoing coronary artery bypass grafting (CABG) receiving...
We present a case of community-acquired methicillin-resistant Staphylococcus aureus necrotizing pneumonia, Panton-Valentine leukocidin positive, in woman at 14 weeks pregnancy. To our knowledge, this is the first reporting critical lung infection occurring during an early phase This study alerts physicians to increasing worldwide spread these uncommon yet virulent and potentially lethal infections. In patient, antibiotic therapy with linezolid plus rifampin started pregnancy had successful...
Abstract Acetylcholine ( AC h) is involved in the modulation of inflammatory response. h levels are regulated by its synthesizing enzyme, choline acetyltransferase (Ch AT ), and hydrolyzing enzymes, mainly acetylcholinesterase hE) butyrylcholinesterase (BuChE). A more comprehensive understanding cholinergic system experimental autoimmune encephalomyelitis EAE ) disease progression could pave path for development therapies to ameliorate multiple sclerosis MS ). In this work, we analyzed...
The aim of this randomised, double-blind study was to investigate the usefulness intravenous nefopam, clonidine or placebo in preventing shivering patients undergoing conscious sedation for interventional neuroradiological procedures. A total 101 were prospectively enrolled and assigned one three groups receive placebo. overall incidence intra-operative significantly lower treated with nefopam than those (2/32 (6%) vs. 11/38 (29%), p < 0.02; 2/32 24/31 (77%), 0.0001, respectively). number...