A5047263544- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- ECG Monitoring and Analysis
- Venous Thromboembolism Diagnosis and Management
- Ion channel regulation and function
- Trauma Management and Diagnosis
- Coronary Interventions and Diagnostics
- Cardiovascular Syncope and Autonomic Disorders
- Cardiovascular Function and Risk Factors
- Heart Failure Treatment and Management
- Peripheral Artery Disease Management
- Cardiovascular and exercise physiology
- Diversity and Career in Medicine
- Liver Disease and Transplantation
- Atherosclerosis and Cardiovascular Diseases
- Cardiovascular Issues in Pregnancy
- Electrodeposition and Electroless Coatings
- Adipokines, Inflammation, and Metabolic Diseases
- Analog and Mixed-Signal Circuit Design
- Ultrasound and Hyperthermia Applications
- Respiratory and Cough-Related Research
- Radiopharmaceutical Chemistry and Applications
- Cardiovascular Effects of Exercise
National Institute of Cardiovascular Diseases
2019-2024
National Institute of Cardiovascular Diseases
2020
Universitair Ziekenhuis Brussel
2014-2016
Art Research Centre of the Slovak Academy of Sciences
2016
Vrije Universiteit Brussel
2014-2015
Erasmus Hospital
2015
Patel Hospital
2009
Liaquat National Hospital
2008
A Comparison Between the First and Second Generation Balloon Background With respect to first generation Cryoballoon (CB), second (Cryoballoon Advance [CB‐A], Medtronic, Minneapolis, MN, USA) was designed with technical modifications resulting in a larger more uniform zone of freezing on balloon's surface aiming at procedural outcome improvement setting atrial fibrillation (AF) ablation. However, comparison between both technologies midterm follow‐up is missing today's literature. Methods...
The second-generation cryoballoon is effective in achieving acute pulmonary vein isolation (PVI) and favorable clinical outcome. To date, no data are available on factors affecting late PV reconnection after ablation.A total of 29 consecutive patients (25 male, 86.2%; mean age 57.8±13.8 years) underwent a repeat procedure, 11.6±4.5 months (range, 3.5-19.7 months), index ablation using the 28-mm cryoballoon. All ablations were performed 3-dimensional electroanatomical mapping system. Among...
To assess the 1 year efficacy of pulmonary vein isolation (PVI) as index procedure for persistent atrial fibrillation (PersAF) comparing conventional radiofrequency irrigated-tip catheter ablation (RFCA) using contact-force technology and second-generation cryoballoon (CB-AdvA). One hundred consecutive patients (74 male, 74%; mean age 62.4 ± 9.6 years) with drug-refractory PersAF undergoing PVI RFCA CB-AdvA were enrolled. Follow-up was based on outpatient clinic visits including...
Background— The prognostic value of electrophysiological investigations in individuals with Brugada syndrome remains controversial. Different groups have published contradictory data. Long-term follow-up is needed to clarify this issue. Methods and Results— Patients presenting spontaneous or drug-induced type I ECG whom programmed electric stimulation was performed at our institution were considered eligible for study. A total 403 consecutive patients (235 males, 58.2%; mean age, 43.2±16.2...
AimsTo assess the incidence of late pulmonary vein (PV) reconnection following index PV isolation (PVI) procedure initially achieved with radiofrequency contact-force catheter ablation (CFCA) and second-generation cryoballoon (CB-AdvA).
Among Brugada syndrome patients, asymptomatic individuals are considered to be at the lowest risk. Nevertheless, arrhythmic events and sudden cardiac death not negligible. Literature focused on this specific group of patients is sparse. The purpose study investigate clinical characteristics, management, long-term prognosis patients.Patients presenting with spontaneous or drug-induced type I ECG no symptoms our institution were eligible. A total 363 consecutive (200 men, 55.1%; mean age,...
Single 3 vs. Double 4 Strategy in CB ablation Introduction Second‐generation cryoballoon (CB‐Adv) is highly effective achieving pulmonary vein isolation (PVI) with promising mid‐term clinical outcome. However, the ideal freezing strategy still under debate. The aim of this study was to assess efficacy a single 3‐minute approach compared conventional 4‐minute plus bonus application using CB‐Adv. Methods and Results One hundred sixty patients (67% male; mean age 58.0 ± 13.3 years) underwent...
<h3>Objectives</h3> Brugada syndrome (BS) in women is considered an infrequent condition with a more favourable prognosis than men. Nevertheless, arrhythmic events and sudden cardiac death (SCD) also occur this population. Long-term follow-up data of group are sparse. The purpose the present study was to investigate clinical characteristics long-term BS. <h3>Methods</h3> A consecutive cohort 228 presenting spontaneous or drug-induced type I ECG at our institution were included compared 314...
AimThe second-generation cryoballoon (CB-Adv) is effective in achieving pulmonary vein isolation (PVI) with encouraging results. In this study, we assessed the single-procedure outcome on a 1-year follow-up period large sample of patients having undergone PVI for drug-resistant atrial fibrillation (AF) using CB-Adv.
Transseptal (TS) catheterization is needed to access the left heart during pulmonary vein isolation (PVI) procedures. In radiofrequency (RF) ablation procedure, atrial commonly achieved with a double TS puncture; cryoballoon (CB) usually requires only single puncture. Our aim was compare incidence of iatrogenic septal defect (IASD) between transseptal conventional RF and CB ablation.Individuals having undergone PVI as index procedure by or subsequent transesophageal echocardiography...
Phrenic nerve injury (PNI) is the most frequently observed complication during pulmonary vein isolation procedure using second-generation cryoballoon (CB). Our objective was to analyse correlation between fluoroscopic position of 28 mm CB ablation in right superior (RSPV) and occurrence PNI.A total 165 patients having undergone large were retrospectively reviewed. Positioning relative cardiac silhouette classified under guidance antero-posterior projection RSPV ablation. Regarding lower half...
The present study sought to analyse the relationship between temperature drop during cryoenergy application and occurrence of phrenic nerve injury (PNI) in a large cohort patients having undergone second-generation cryoballoon ablation (CB-A).The first 550 consecutive CB-A for atrial fibrillation were enrolled. Attained temperatures at 20, 30, 40, 60 s cryoablation right-sided pulmonary veins (PVs) collected. Diagnosis PNI was made if reduced motility or paralysis hemidiaphragm detected....
The phenotypic heterogeneity of Brugada syndrome (BrS) can lead some patients to show an additional inferolateral early repolarization pattern (ERP), or fragmented QRS (f-QRS). aim the study was investigate prevalence and clinical impact f-QRS, ERP combined f-QRS/ERP in high-risk with BrS.Patients spontaneous drug-induced BrS indication receive implantable cardioverter-defibrillator (ICD) were considered eligible for this study. From 1992 2012, a total 176 consecutive underwent ICD...
In order to increase success rates of invasive treatment persistent atrial fibrillation, the hybrid approach was developed, combining video-assisted thoracoscopic epicardial procedure with conventional endocardial catheter ablation. Currently, there are no reports electrophysiological findings and clinical outcomes repeat procedures after approach.Out 64 patients who were treated by ablation for fibrillation (AF), 14 underwent selected this study. All initially presented longstanding...
Background Phrenic nerve palsy (PNP) is the most frequently observed complication in setting of cryoballoon (CB) ablation (Arctic Front, Medtronic Inc., Minneapolis, MN, USA). Although, usually transient, resolving before end procedure, persistent PNP (not procedure) can occur. Literature on after second generation CB relatively sparse. Methods A total 316 consecutive patients having undergone large 28‐mm as index procedure Heart Rhythm Management Center, UZ Brussels, Belgium, from January...