A5049168398- Nanomaterials for catalytic reactions
- Catalytic Cross-Coupling Reactions
- Multicomponent Synthesis of Heterocycles
- Synthesis and Characterization of Heterocyclic Compounds
- Oxidative Organic Chemistry Reactions
- Nuclear Structure and Function
- Magnetic properties of thin films
- RNA Research and Splicing
- Chemical Synthesis and Analysis
- Quinazolinone synthesis and applications
- Asymmetric Hydrogenation and Catalysis
- RNA modifications and cancer
- Electrocatalysts for Energy Conversion
- Chemical synthesis and alkaloids
- Molecular Junctions and Nanostructures
- Synthesis and biological activity
- HIV/AIDS drug development and treatment
- HIV Research and Treatment
- RNA Interference and Gene Delivery
Laboratoire des Biomolécules
2016
Abivax (France)
2015
University of Edinburgh
2006-2008
Evotec (United Kingdom)
2006
GlaxoSmithKline (United Kingdom)
2006
Current therapies have succeeded in controlling AIDS pandemic. However, there is a continuing need for new drugs, particular those acting through and as yet unexplored mechanisms of action to achieve HIV infection cure. We took advantage the unique feature proviral genome require both activation inhibition splicing viral transcripts develop molecules capable achieving long lasting effect on replication humanized mouse models Rev-mediated RNA biogenesis.Current reduce load during treatment...
Polystyrene-poly(ethylene glycol) resin-captured cross-linked palladium nanopaticles were prepared via a straightforward route, and their heterogeneous behavior was truly confirmed by various tests. They applied to aqueous Suzuki cross-coupling reactions with aryl bromides recycled up six times without loss of activity.
Palladium nanoparticles were entrapped within resin plugs and used in a range of ligand-free cross-coupling reactions; the convenient modular format plug enhanced handling allowed catalysts to be easily recovered multiply reused.
Compounds belonging to the 5-acyl-3,4-dihydropyrimidine-2-thione family were obtained using a solvent-free Biginelli condensation with or without use of catalyst. An unprecedented solid-phase procedure involving polymer-supported aldehyde allowed preparation series 5-aroyl derivatives starting crude diketones from their corresponding aryl esters.
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at glance that was extracted from about 200 leading journals. To access of an article which published elsewhere, please select “Full Text” option. The original trackable via the “References”
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at glance that was extracted from about 200 leading journals. To access Abstract, please click on HTML or PDF.
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at glance that was extracted from about 200 leading journals. To access of an article which published elsewhere, please select “Full Text” option. The original trackable via the “References”