- Neurotransmitter Receptor Influence on Behavior
- Cannabis and Cannabinoid Research
- Forensic Toxicology and Drug Analysis
- Psychedelics and Drug Studies
- Pain Mechanisms and Treatments
- Opioid Use Disorder Treatment
- Neuroscience and Neuropharmacology Research
- Pharmacological Effects and Assays
- Nicotinic Acetylcholine Receptors Study
- Stress Responses and Cortisol
- Treatment of Major Depression
- Neuroscience of respiration and sleep
- Neuropeptides and Animal Physiology
- Smoking Behavior and Cessation
- Tryptophan and brain disorders
- Biochemical effects in animals
- Neurobiology and Insect Physiology Research
- Hormonal and reproductive studies
- Sleep and Wakefulness Research
- HIV Research and Treatment
- Neurogenesis and neuroplasticity mechanisms
- Alcohol Consumption and Health Effects
- Parkinson's Disease Mechanisms and Treatments
- Neurological disorders and treatments
- GABA and Rice Research
Baylor University
2022-2024
University of California, San Diego
2017-2023
Scripps Research Institute
2016-2023
La Jolla Alcohol Research
2017-2023
Center for Occupational Research and Development
2022-2023
Washington State University
2022
National Institute of Mental Health
2022
Columbia University Irving Medical Center
2022
University of North Texas
2011-2014
University of North Texas Health Science Center
2011-2014
Background and Purpose Adolescents are regularly exposed to ∆ 9 ‐tetrahydrocannabinol (THC) via smoking and, more recently, vaping cannabis extracts. Growing legalization of for medical recreational purposes, combined with decreasing perceptions harm, makes it increasingly important determine the consequences frequent adolescent exposure motivated behaviour lasting tolerance in response THC. Experimental Approaches Male female rats inhaled THC vapour, or that from propylene glycol (PG)...
The recreational use of substituted cathinones continues to grow as a public health concern in the United States. Studies have shown that extended access intravenous (i.v.) self-administration stimulants, such cocaine and methamphetamine, results escalation drug intake relative shorter access; however, little is known about impact on entactogen class stimulants methylone 4-methylmethcathinone (mephedrone). Male Wistar rats were randomly assigned short-access (ShA, 2- h) long-access (LgA, 6-...
Background and Purpose The extra medical use of, addiction to, prescription opioid analgesics is a growing health problem. To characterize how abuse develops, this study investigated the affective consequences of escalating using intracranial self‐stimulation (ICSS) reward oxycodone intravenous self‐administration (IVSA) models. Experimental Approach Male Wistar rats were given access to IVSA (0.15 mg·kg −1 per infusion, i.v.) in short‐access (ShA; 1 h) or long‐access (LgA; 12 sessions for...
There has been a resurgence in nicotine inhalation adolescents due to the popularity and availability of Electronic Nicotine Delivery Systems (ENDS). Almost five times as many US high-school seniors inhale vapor daily compared with those who smoke tobacco. This study was conducted determine impact repeated adolescent on behavior adulthood.
The α-pyrrolidino-phenone cathinone stimulants first came to widespread attention because of bizarre behavior consequent the use α-pyrrolidinopentiophenone (α-PVP, "flakka") reported in popular press. As with other designer drugs, diversification cathinones has been driven by desirable subjective effects, but also attempts stay ahead legal controls specific molecules. α-pyrrolidinohexiophenone (α-PHP) and α-pyrrolidinopropiophenone (α-PPP) compounds have relatively under-investigated...
HIV-associated neurocognitive disorders (HAND) persist despite the advent of antiretroviral therapy (ART), suggesting underlying systemic and central nervous system (CNS) inflammatory mechanisms. The endogenous cannabinoid receptors 1 2 (CB1 CB2) modulate gene expression play an important role in maintaining neuronal homeostasis. Cannabis use is disproportionately high among people with HIV (PWH) may provide a neuroprotective effect for those on ART due to its anti-inflammatory properties....