Alfons Fischer

ORCID: 0000-0003-0407-2813
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About
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Research Areas
  • Orthopaedic implants and arthroplasty
  • Advanced materials and composites
  • Metal Alloys Wear and Properties
  • Metal and Thin Film Mechanics
  • Tribology and Wear Analysis
  • Hydrogen embrittlement and corrosion behaviors in metals
  • Mechanical stress and fatigue analysis
  • Orthopedic Infections and Treatments
  • Titanium Alloys Microstructure and Properties
  • Microstructure and Mechanical Properties of Steels
  • Adhesion, Friction, and Surface Interactions
  • Lubricants and Their Additives
  • Bone Tissue Engineering Materials
  • Coronary Interventions and Diagnostics
  • High-Temperature Coating Behaviors
  • Medical and Health Sciences Research
  • Welding Techniques and Residual Stresses
  • Health and Medical Studies
  • Additive Manufacturing Materials and Processes
  • Corrosion Behavior and Inhibition
  • Diamond and Carbon-based Materials Research
  • Powder Metallurgy Techniques and Materials
  • Engineering and Materials Science Studies
  • Tribology and Lubrication Engineering
  • Additive Manufacturing and 3D Printing Technologies

Rush University Medical Center
2012-2024

Max-Planck-Institut für Nachhaltige Materialien
2020-2024

Heinrich Heine University Düsseldorf
1995-2024

Düsseldorf University Hospital
2024

University of Duisburg-Essen
2012-2021

Smith College
2021

Syracuse University
2021

John Wiley & Sons (United States)
2021

Essen University Hospital
1999-2003

Mercator Institute for China Studies
2003

Abstract Wear-related energy and material loss cost over 2500 Billion Euro per year. Traditional wisdom suggests that high-strength materials reveal low wear rates, yet, their plastic deformation mechanisms also influence performance. High strength homogeneous behavior, which allow accommodating strain without cracking or localized brittle fracture, are crucial for developing wear-resistant metals. Here, we present an approach to achieve superior resistance via in-situ formation of a strong...

10.1038/s41467-021-25778-y article EN cc-by Nature Communications 2021-09-17

A graphitic layer is found to be the cause of low friction in metal-on-metal hip implants.

10.1126/science.1213902 article EN Science 2011-12-22

Recently, “ tribocorrosion, ” a research area combining the science of tribology and corrosion, has drawn attention from scientists engineers belonging to wide spectrum domains. This is due its practical impact on daily life also accompanying economical burdens. It encompasses numerous applications including offshore, space, biomedical industry, for instance, in case artificial joints (Total Hip Replacement, THR) orthopedic surgery, where implant metals are constantly exposed tribological...

10.1155/2009/250986 article EN cc-by Advances in Tribology 2009-01-01

Metal-on-metal (MoM) bearings are at the forefront in hip resurfacing arthroplasty. Because of their good wear characteristics and design flexibility, MoM gaining wider acceptance with market share reaching nearly 10% worldwide. However, concerns remain regarding potential detrimental effects metal particulates ion release. Growing evidence is emerging that local cell response related to amount debris generated by these bearing couples. Thus, an urgent clinical need exists delineate...

10.1002/jor.21020 article EN Journal of Orthopaedic Research® 2009-01-01

Metal-on-metal bearing couples remain a popular option in total hip arthroplasty and are the only currently available for surface replacement arthroplasty. In general, intermediate-term clinical performance of metal-on-metal bearings has been favorable. There are, however, lingering concerns about biologic consequences metal release from these terms both local tissue effects, including delayed-type hypersensitivity reactions subset patients, potential systemic effects as consequence chronic...

10.5435/00124635-200902000-00003 article EN Journal of the American Academy of Orthopaedic Surgeons 2009-02-01

After the rapid growth in use of CoCrMo metal-on-metal hip replacements since second generation was introduced circa 1990, have experienced a sharp decline last two years due to biocompatibility issues related wear and corrosion products. Despite some excellent clinical results, release debris adverse response local tissues been great concern. There are many unknowns regarding how metal bearings interact with human body. This perspective article is intended outline recent progresses...

10.1039/c2cp42968c article EN Physical Chemistry Chemical Physics 2012-11-07

ABSTRACT Wear of the modular taper between head and shaft has been related to clinical failure resulting from adverse reactions metallic debris. The problem become pronounced in large metal‐on‐metal bearings, but mechanism not yet fully understood. We analyzed retrieved components five patients revised with various diagnoses. Two distinct wear patterns were observed for tapers. Three samples demonstrated “asymmetric” towards inner end taper. other two showed “axisymmetric” radial (up 65 µm)...

10.1002/jor.22326 article EN Journal of Orthopaedic Research® 2013-02-25

10.1016/j.jmbbm.2012.03.013 article EN Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials 2012-03-28

10.1016/j.jmbbm.2012.01.007 article EN Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials 2012-01-29

10.1016/j.jmbbm.2013.08.018 article EN Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials 2013-09-03

Abstract To overcome the problem of in‐stent restenosis, concept local delivery antiproliferative or immunosuppressive drugs has been introduced into interventional cardiology. Local drug can be achieved by drug‐eluting stents coated with polymer surfaces used for controlled release. However, several coatings have shown an induction inflammatory response and increased neointima formation. In present study, effect a new inorganic ceramic nanoporous aluminum oxide (Al 2 O 3 ) coating on...

10.1002/ccd.10664 article EN Catheterization and Cardiovascular Interventions 2003-10-15

Abstract To control and minimize wear of metal‐on‐metal hip joints it is essential to understand the mechanisms debris generation. In vivo , mainly nanosize globular needle‐shaped particles are found. These can neither stem from action abrasion nor tribochemical reactions. this study acting have been first identified on surface by means scanning electron microscopy (SEM). Afterwards, microstructures subsurface regions explants investigated using a transmission microscope (TEM). Observation...

10.1002/jbm.b.30132 article EN Journal of Biomedical Materials Research Part B Applied Biomaterials 2004-10-20

Abstract Millions worldwide suffer from arthritis of the hips, and total hip replacement is a clinically successful treatment for end‐stage patients. Typical implants incorporate cobalt alloy (Co–Cr–Mo) femoral head fixed on titanium (Ti‐6Al‐4V) stem via Morse taper junction. However, fretting corrosion at this junction can cause release wear particles metal ions metallic implant, leading to local systemic toxicity in This study multiscale structural‐chemical investigation, ranging...

10.1002/advs.201903008 article EN cc-by Advanced Science 2020-01-21
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