A5100634193- Spine and Intervertebral Disc Pathology
- Musculoskeletal pain and rehabilitation
- Clinical practice guidelines implementation
- Lymphoma Diagnosis and Treatment
- Plant Toxicity and Pharmacological Properties
- Prenatal Screening and Diagnostics
- Healthcare and Venom Research
- Blood groups and transfusion
- Mass Spectrometry Techniques and Applications
- Bone and Joint Diseases
- Cutaneous lymphoproliferative disorders research
- Viral-associated cancers and disorders
- Neonatal Health and Biochemistry
- Trace Elements in Health
- RNA and protein synthesis mechanisms
- TGF-β signaling in diseases
- Sperm and Testicular Function
- Medical and Biological Sciences
- T-cell and Retrovirus Studies
- Spondyloarthritis Studies and Treatments
- Shoulder Injury and Treatment
- CAR-T cell therapy research
- Chromosomal and Genetic Variations
- Bone Metabolism and Diseases
- Iron Metabolism and Disorders
Peking University
2025
Peking University Cancer Hospital
2025
Inner Mongolia Medical University
2025
Fudan University
2022
Inner Mongolia University
2019-2020
Second Affiliated Hospital of Inner Mongolia Medical University
2019
University of Washington
2011
North University of China
2007
National University of Singapore
2005
Jewish Hospital
2002
Plasma ferritin is an important extracellular iron storage molecule, whose concentration increases drastically in cancer and infection. During infection, the pathogen usurps host for its survival pathogenicity; hence, maintenance of plasma level during infection a crucial defence mechanism. In this study, horseshoe crab complex was purified, characterized, involvement innate immune investigated. The appears as 21-kDa subunit on SDS-PAGE. Full-length ferritin-H cDNAs (CrFer-H1 CrFer-H2) were...
Abstract Type II collagen can be synthesized in two forms generated by alternative splicing of the precursor mRNA. IIA procollagen, which contains a cysteine‐rich domain NH 2 ‐propeptide (exon 2), is produced precartilage and noncartilage epithelial mesenchymal cells, type IIB without domain, characteristic chondrocytes. Mice lacking fail to develop intervertebral discs. We have previously shown that human disc notochord synthesize primarily form procollagen. Therefore, we investigated...
Immunohistochemical analysis of type IX collagen in disc tissue from spinal fusion patients.To determine if can be detected adult removed at surgery patients either with or without degeneration-associated tryptophan single nucleotide polymorphisms (SNPs) and whether the distribution is associated severity degeneration incidence a SNP genotype.Genetic factors are strongly risk development and/or progression degeneration. Two SNPs that introduce COL9A2 COL9A3 independently linked to an...
Lumbar disc herniation, a type of chronic low back pain syndrome, is caused by the lumbar intervertebral disk degeneration. Genetic variation in CHRNA5/CHRNA3 has shown strong associations with smoking-related diseases. This study's aim to test whether single-nucleotide polymorphisms gene are associated herniation risk.The genotype frequency distributions were detected polymerase chain reaction-restriction fragment length polymorphism 380 patients (case group) and 400 healthy individuals...
Abstract Background Lumbar disk herniation (LDH) is a degenerative disorder, which partly results from complex genetic factors. The aim of the study was to investigate potential associations between glypican‐6 ( GPC6 ) variants and LDH risk in Han Chinese population. Methods A total 508 patients healthy controls were recruited this study. Six single‐nucleotide polymorphisms (SNPs) selected genotyped using an Agena MassARRAY platform. We used logistic regression method evaluate linkage by...
Fluorescence in situ hybridization analysis of numerical chromosomal abnormalities the sperm Robertsonian translocation der (13;14) (q10;q10) carriers has focused on a limited number chromosomes mainly chromosome 13, 18, 21, X, and Y. Here, we aimed to expand all by increasing probes analyzed fluorescence hybridization. The incidence (1–22, Y) was determined from 10 der(13;14)(q10;q10) normozoospermic males fully assess effect translocation-derived segregation during meiosis. Numerical two...
Conference Abstract| October 01 2002 Collagen gene expression in intervertebral disc development Linda J. Sandell; Sandell 1Washington University School of Medicine at Barnes-Jewish Hospital, Department Orthopaedic Surgery, 216 South Kingshighway, St Louis, Missouri 63110 Search for other works by this author on: This Site PubMed Google Scholar Yong Zhu; Zhu Audrey McAlinden Author and article information Publisher: Portland Press Ltd Online ISSN: 1470-8752 Print 0300-5127 © Biochemical...