- Effects of Environmental Stressors on Livestock
- Thermoregulation and physiological responses
- Meat and Animal Product Quality
- Insect Resistance and Genetics
- Vector-borne infectious diseases
- Adipose Tissue and Metabolism
- Forensic Entomology and Diptera Studies
- Bacterial Genetics and Biotechnology
- Climate Change and Health Impacts
- Biochemical and Structural Characterization
- RNA modifications and cancer
- Insect symbiosis and bacterial influences
- Genetic and phenotypic traits in livestock
- Signaling Pathways in Disease
- DNA Repair Mechanisms
- Mitochondrial Function and Pathology
- Enzyme Structure and Function
Commonwealth Scientific and Industrial Research Organisation
1992-2025
Agriculture and Food
2020-2025
Animal, Food and Health Sciences
2014
The University of Queensland
2002-2003
The bacterial replisome is a target for the development of new antibiotics to combat drug resistant strains. β2 sliding clamp an essential component replicative machinery, providing platform recruitment and function other replisomal components ensuring polymerase processivity during DNA replication repair. A single binding region utilized by its partners, which all contain conserved motifs. C-terminal Leu Phe residues these motifs are integral interaction. We acquired three-dimensional...
The extent of endocrine changes in response to various levels heat stress and subsequent recovery is not well understood. Two cohorts 12 Black Angus steers were housed climate-controlled rooms (CCR) subjected three thermal periods: PreChallenge (5 d), Challenge (7 d) Recovery d). provided thermoneutral conditions. simulated a strong heatwave. Finally, the maintained outdoor pens for 38 d. Rumen temperature (RumT), respiration rate (RR) panting score (PS) intensively measured CCR. Dry matter...
We set out to determine the impact of moderate heat load on plasma concentrations a suite hormones involved in regulating energy metabolism and feed intake. The responses thermally challenged (TC) feedlot steers were compared those restricted thermoneutral (FRTN) steers. Two sequential cohorts twelve 518 ± 23 kg Black Angus finisher grain ration housed climate-controlled rooms (CCR) for 18 days returned outdoor pens 40 days. TC group was subjected diurnal range 28-35 °C 7 (Challenge) but...
Abstract Given the climate projections for livestock rearing regions globally, understanding inflammatory status of under various heat loads will be informative to animal welfare and management. A survey plasma markers was conducted, blood leucocyte counts followed investigate capacity ~ 500 kg grain fed Black Angus steer respond recover from a moderate load challenge. Two sequential cohorts 12 steers were housed in climate-controlled rooms (CCR) 18 days. thermally challenged (TC) group ( n...
Muscle development and remodelling, mitochondrial physiology inflammation are thought to be inter-related have implications for metabolism in both health disease. However, our understanding of their molecular control is incomplete.In this study we confirmed that the ring finger 14 protein (RNF14), a poorly understood transcriptional regulator, influences expression immune-related genes. The prediction was based on combination network connectivity differential cattle (a non-model organism)...
Close-to-market weight grain fed cattle experience high heat loads during summer. There are health, welfare and production impacts on these value animals. Two cohorts of 600 kg Black Angus steers (n = 12) were subjected to heatwave conditions a thermal challenge in climate chambers. Frequent blood sampling enabled detailed description the metabolic endocrine trajectories load recovery feedlot cattle. In ruminants, flow is diverted from major organs impacting rate cellular functions. The will...