A5089902597- Reproductive Physiology in Livestock
- Growth Hormone and Insulin-like Growth Factors
- Veterinary Equine Medical Research
- Hypothalamic control of reproductive hormones
- Adipose Tissue and Metabolism
- Genetic and phenotypic traits in livestock
- Urban and Freight Transport Logistics
- Health Sciences Research and Education
- Regulation of Appetite and Obesity
- Ruminant Nutrition and Digestive Physiology
- Birth, Development, and Health
- Neuropeptides and Animal Physiology
- Family Business Performance and Succession
- Regional Development and Policy
- Effects of Environmental Stressors on Livestock
- Private Equity and Venture Capital
- Pharmaceutical Practices and Patient Outcomes
- Veterinary Medicine and Surgery
- Neuroendocrine regulation and behavior
- Cytokine Signaling Pathways and Interactions
- Voice and Speech Disorders
- Diabetes and associated disorders
- Soil and Water Nutrient Dynamics
- Animal Behavior and Welfare Studies
- Stress Responses and Cortisol
The University of Queensland
2016-2025
The Ohio State University
2023
Riverside Methodist Hospital
2023
National Cancer Institute
2012-2022
The University of Texas at Austin
2020
Renishaw (United Kingdom)
2015
Indiana University School of Medicine
2014
Indiana University – Purdue University Indianapolis
2014
Brighton and Sussex Medical School
2009
University of Westminster
1996-2005
A new method for typing single nucleotide polymorphisms in DNA is described. In this method, specific fragments of genomic containing the polymorphic site(s) are first amplified by polymerase chain reaction (PCR) using one regular and phosphorothioate-modified primer. The doublestranded PCR product rendered single-stranded treatment with enzyme T7 gene 6 exonuclease, captured onto individual wells a 96 well polystyrene plate hybridization to an immobilized oligonucleotide This primer...
Maternal exposure to increased synthetic glucocorticoids (GC) during pregnancy is known disturb fetal development and increase the risk of long-term disease. elevated levels natural GC likely be common yet relatively understudied. The placenta plays an important role in regulating maternal but itself vulnerable insults. This study uses a mouse model corticosterone (Cort) investigate its effects on developing placenta. Mice were treated with Cort (33 μg/kg·h) for 60 h starting at embryonic d...
Alcohol consumption throughout pregnancy can cause metabolic dysregulation, including glucose intolerance in progeny. This study determined if periconceptional (PC) alcohol (12% v/v a liquid diet) (PC:EtOH) consumed exclusively around conception results similar outcomes Sprague-Dawley rats. Control (C) rats were given diet containing no but matched to ensure equal caloric intake. PC maternal intake (from 4 days before until day of gestation), resulted offspring with elevated fasting plasma...
To succeed at post-secondary education, it's essential that students develop an understanding of their own knowledge and learning processes. This metacognition learning, or 'meta-learning', helps to become more effective learners, as they aware self-regulatory processes recognise the effectiveness study strategies. increase biomedical science students' self-awareness, we have designed implemented meta-learning assessment tasks across our courses. Most reported had a positive impact on...
Abstract Suppressor of cytokine signaling 3 (SOCS3), as a key regulator signaling, has the potential to modulate numerous cellular processes. Its involvement in inflammatory disease is well established, and there increasing evidence for role breast cancer signal transducers activators transcription (STATs). Here we show that over‐expression SOCS3 markedly supresses STAT3 expression, abrogates STAT5 phosphorylation, resulting decreased cell proliferation T47D cells, anchorage‐independent...
<h3>Background</h3> The value of interferon-γ release assays (IGRA) to diagnose active tuberculosis (TB) in children is not established, but these are being widely used for this purpose. authors examined the sensitivity commercially available IGRA TB UK compared with tuberculin skin test (TST). <h3>Methods</h3> established a paediatric network and conducted retrospective analysis data from investigated at six large centres. All centres had TST least one (T-Spot.TB or Quantiferon-Gold Tube)...
Context Pastures growing on low phosphorus (P) soils are often P deficient, particularly for lactating cows.Aim To examine the effects of P-deficient diets performance multiparous cows.Methods From parturition, mature Bos indicus cross cows (n=32, initially 474kg liveweight (LW) and body condition score 3.5) were fed ad libitum 14weeks one four diets: (i) high (HP-HCa), (ii) with calcium (LP-LCa), (iii) Ca (LP-HCa), or (iv) LP-LCa diet ammonium chloride (LP-LCa+ac).Results Voluntary feed...
The extent of endocrine changes in response to various levels heat stress and subsequent recovery is not well understood. Two cohorts 12 Black Angus steers were housed climate-controlled rooms (CCR) subjected three thermal periods: PreChallenge (5 d), Challenge (7 d) Recovery d). provided thermoneutral conditions. simulated a strong heatwave. Finally, the maintained outdoor pens for 38 d. Rumen temperature (RumT), respiration rate (RR) panting score (PS) intensively measured CCR. Dry matter...
Objective. To elucidate the ability of pharmacy students to self-regulate their learning, and determine impact self-regulatory behaviors on learning outcomes. Methods. This study took a mixed methods approach that used "meta-learning" assessment tasks identify strategies chosen relied by 139 second-year students, relationships between quality academic achievement. Results. Although had previously tried wide range strategies, they only consistently rely few them. When prompted use more...
Generalized obesity, regional adiposity, hyperinsulinemia and hypertriglyceridemia are all potential indicators of equine metabolic syndrome (EMS). This study aimed to assess the relationship between morphometric measurements body condition hormone concentrations in ponies, with without a neck crest or generalised obesity. Twenty-six ponies were assigned score (BCS) cresty (CNS). Height, girth, taken. An oral glucose test (OGT; 0.75g dextrose/kg BW) was performed blood samples collected...
The development of pathologies during pregnancy, including pre-eclampsia, hypertension and fetal growth restriction (FGR), often originates from poor functioning the placenta.
Selenium is an essential micronutrient commonly deficient in human populations. deficiency increases the risks of pregnancy complications; however, long-term impact selenium on offspring disease remains unclear. This study investigates effects during metabolic function. Female C57BL/6 mice were allocated to control (>190 μg selenium/kg, n = 8) or low (<50 diets prior mating and throughout gestation. At postnatal day (PN) 170, underwent intraperitoneal glucose tolerance test culled at PN180...
London's air quality has improved over recent decades, but is still the worst in UK. Road transport emissions play an important part this pollution. A low emission zone (LEZ) would help to accelerate introduction of cleaner vehicles, and reduce number older, more polluting vehicles operating London. Survey results indicate that there some support among goods vehicle operators for a LEZ London, depending on precise scheme definition. Operators generally try comply with regulations, most...
Summary Reasons for performing study: In Australia, there have been recent reports of unusual abortions in mid‐ to late‐gestation mares. These were clinically distinct from other recognised causes pregnancy loss and the term ‘equine amnionitis fetal loss’ (EAFL) was adopted describe this syndrome. Initial investigations concluded that possible causal factors included presence on affected stud farms Processionary caterpillars ( Ochrogaster lunifer ). Objectives: To determine if exposure...
The effects of maternal alcohol consumption around the time conception on offspring are largely unknown and difficult to determine in a human population. This study utilized rodent model examine if periconceptional (PC:EtOH) consumption, alone or combination with postnatal high-fat diet (HFD), resulted obesity liver dysfunction. Sprague-Dawley rats were fed control an ethanol-containing [12.5% (vol/vol) EtOH] liquid from 4 days before mating until gestation ( n = 12/group). A subset was HFD...
The liver plays a central role in metabolism and produces important hormones. Hepatic estrogen receptors the release of insulin-like growth factor one (IGF1) are critical links between function reproductive system. However, pubertal development is not fully understood. To explore this question, we applied transcriptomic analyses to samples pre- post-pubertal Brahman heifers identified differentially expressed (DE) genes encoding transcription factors (TF). Differential expression suggest...