A5044272112- Colorectal Cancer Screening and Detection
- Global Cancer Incidence and Screening
- Genetic factors in colorectal cancer
- Tuberculosis Research and Epidemiology
- Marine and fisheries research
- Pneumocystis jirovecii pneumonia detection and treatment
- HIV/AIDS drug development and treatment
- Respiratory viral infections research
- HIV/AIDS Research and Interventions
- Fish Ecology and Management Studies
- Demographic Trends and Gender Preferences
- HIV Research and Treatment
- Colorectal Cancer Surgical Treatments
- Lung Cancer Research Studies
- Economic and Financial Impacts of Cancer
- Lung Cancer Treatments and Mutations
- HIV-related health complications and treatments
- Coral and Marine Ecosystems Studies
- Respiratory and Cough-Related Research
- Infectious Diseases and Tuberculosis
- Marine animal studies overview
- Marine Bivalve and Aquaculture Studies
- Anthropological Studies and Insights
- Streptococcal Infections and Treatments
- Global Health Care Issues
London School of Hygiene & Tropical Medicine
2014-2024
University of Wisconsin–Madison
2023-2024
University of Wisconsin Health
2024
Velindre Cancer Centre
2024
Warwick Hospital
2021
Gloucestershire Hospitals NHS Foundation Trust
2021
Cancer Research UK
2010-2015
Imperial College Healthcare NHS Trust
2014
Imperial College London
1999-2014
St Mary's Hospital
1996-2014
<h3>Background</h3> The authors consider whether differences in stage at diagnosis could explain the variation lung cancer survival between six developed countries 2004–2007. <h3>Methods</h3> Routinely collected population-based data were obtained on all adults (15–99 years) diagnosed with 2004–2007 and registered regional national registries Australia, Canada, Denmark, Norway, Sweden UK. Stage for 57 352 patients consolidated from various classification systems. Flexible parametric hazard...
Background. Large international differences in colorectal cancer survival exist, even between countries with similar healthcare. We investigate the extent to which stage at diagnosis explains these differences. Methods. Data from population-based registries Australia, Canada, Denmark, Norway, Sweden and UK were analysed for 313 852 patients diagnosed colon or rectal during 2000–2007. compared distributions of diagnosis. estimated both stage-specific net excess hazard death up three years...
BackgroundThe National Health Service (NHS) cancer plan for England was published in 2000, with the aim of improving survival patients cancer. By contrast, a formal strategy not implemented Wales until late 2006. data on patient and up to 2007 thus offer opportunity first assessment England, by comparing trends those before, during, after implementation plan.MethodsWe analysed population-based 2·2 million adults diagnosed one 21 common cancers during 1996–2006 followed Dec 31, 2007. We...
Socioeconomic inequalities in survival were observed for many cancers England during 1981–1999. The NHS Cancer Plan (2000) aimed to improve and reduce these inequalities. This study examines trends the deprivation gap cancer after implementation of Plan. We examined relative among adults diagnosed with 1 21 common 1996–2006, followed up 31 December 2007. Three periods defined: 1996–2000 (before Plan), 2001–2003 (initialisation) 2004–2006 (implementation). estimated difference between most...
Data are lacking on the performance of interferon-gamma release assays (IGRAs) in children. Although IGRAs recommended for screening latent tuberculosis infection (LTBI), many clinicians wish to employ them as a diagnostic test active (TB). The objective present study was compare two commercially available and tuberculin skin (TST) side-by-side children with TB LTBI. In prospective study, 209 were investigated (n = 91) or 118). TST, QuantiFERON-TB Gold In-tube (QFG-IT; Cellestis, Carnegie,...
The International Cancer Benchmarking Partnership is investigating cancer survival differences between six high-income nations using population-based registry data. Differences in overall are often explained by the stage at diagnosis and stage-specific survival. Comparing data challenging because of different regional practices defining stage, despite existence international staging classifications such as TNM. This paper describes how may be reconciled for analysis. Population-based were...
BackgroundSurvival from colorectal cancer has been shown to be lower in Denmark and England than comparable high-income countries. We used data national registries assess whether differences the proportion of patients receiving resectional surgery could contribute international survival.MethodsIn this population-based study, we collected all aged 18–99 years diagnosed with primary, invasive, adenocarcinoma Jan 1, 2010, Dec 31, 2012, Denmark, England, Norway, Sweden, registries. estimated...
We provide an up-to-date international comparison of cancer survival, assessing whether England is 'closing the gap' compared with other high-income countries.
Background Cancer Waiting Time targets have been integrated into successive cancer strategies as indicators of care quality in England. These are reported national statistics for all cancers combined, but there is mixed evidence their benefits and it unclear if meeting targets, currently defined published, associated with improved survival individual patients, thus a good metric judging the utility targets. Methods findings We used individually-linked data from National Times Monitoring...
MEPS Marine Ecology Progress Series Contact the journal Facebook Twitter RSS Mailing List Subscribe to our mailing list via Mailchimp HomeLatest VolumeAbout JournalEditorsTheme Sections 394:231-245 (2009) - DOI: https://doi.org/10.3354/meps08262 Defining a spawning population (spotted seatrout Cynoscion nebulosus) over temporal, spatial, and demographic scales Susan K. Lowerre-Barbieri1,*, Nathan Henderson2, Joel Llopiz3, Sarah Walters1, Bickford1, Robert Muller1 1Florida Fish Wildlife...
<h3>Background</h3> The value of interferon-γ release assays (IGRA) to diagnose active tuberculosis (TB) in children is not established, but these are being widely used for this purpose. authors examined the sensitivity commercially available IGRA TB UK compared with tuberculin skin test (TST). <h3>Methods</h3> established a paediatric network and conducted retrospective analysis data from investigated at six large centres. All centres had TST least one (T-Spot.TB or Quantiferon-Gold Tube)...
Abstract The spatial distribution of spawning activity can affect the reproductive success certain fishes, and locating key areas is critical to accurately assessing managing their populations. We determined estuarine locations for spotted seatrout Cynoscion nebulosus during 2004 summer season in Tampa Bay, Florida, using a passive acoustic survey. Sound production was evaluated at each 754 randomly selected stations number individuals calling ranged from 1‐2 large aggregations. Spawning...
Reproductive behavior affects spatial population structure and our ability to manage for sustainability in marine diadromous fishes. In this study, we used fishery independent capture-based sampling evaluate where Common Snook occurred Tampa Bay if it changed with spawning season, passive acoustic telemetry assess fine scale at an inlet site (2007-2009). concentrated three areas during the season only one of which fell within expected habitat. Although lower numbers, they remained these...
MEPS Marine Ecology Progress Series Contact the journal Facebook Twitter RSS Mailing List Subscribe to our mailing list via Mailchimp HomeLatest VolumeAbout JournalEditorsTheme Sections 481:181-197 (2013) - DOI: https://doi.org/10.3354/meps10224 Site fidelity and reproductive timing at a spotted seatrout spawning aggregation site: individual versus population scale behavior Susan K. Lowerre-Barbieri*, Sarah Walters, Joel Bickford, Wade Cooper, Robert Muller Florida Fish Wildlife Conservation...
Chickenpox is generally considered to be a benign self limiting illness in children. Indeed, mild secondary bacterial infection of the skin, little clinical importance, most common complication varicella virus infection.1 2 There has been recent increase reports serious infections, however, both during or after chickenpox. We reviewed case notes 13 children (mean age 30 months; seven boys, six girls) who presented our unit over 12 months (1994-5) with sepsis associated chickenpox. We also...
<h3>Background</h3> In July 2008 a case of smear-positive pulmonary tuberculosis (TB) in white UK-born nursery teacher was notified London. The had been symptomatic for 9 months while working the nursery. outbreak is described and protective effect BCG vaccination against latent <i>Mycobacterium tuberculosis</i> infection as measured by an interferon gamma release assay (IGRA) assessed. <h3>Methods</h3> Screening chest X-ray IGRA children, staff their contacts conducted using 'stone-in-the...
Stage is a key predictor of cancer survival. Complete staging vital for understanding outcomes at population level and monitoring the efficacy early diagnosis initiatives. Cancer registries usually collect details disease extent but information may be missing because stage was never assigned to patient or it not included in registration records. Missing introduce methodological difficulties analysis interpretation results. We describe associations between socio-demographic clinical...
Rising greenhouse gas levels heat the earth's surface and alter climate patterns, posing unprecedented threats to planetary ecology human health. At same time, obesity, diabetes, cardiovascular disease have reached epidemic proportions across globe, caused in part by decreases physical activity over-consumption of carbon-intensive foods. Thus, interventions that support active transportation (walking or cycling rather than driving) healthier food choices (eating plant-based meat-based diets)...
Abstract BACKGROUND Prostate cancer linkage studies have been used to localize rare and presumably highly penetrant susceptibility genes. Underlying genetic heterogeneity, as well the high sporadic background of disease, has resulted in many signals that are often not reproducible between research studies. METHODS We conducted a SNP‐based genome wide scan on 131 Caucasian prostate families participating University Michigan Cancer Genetics Project (PCGP). RESULTS The strongest evidence for...
<h3>Background</h3> Reducing geographical inequalities in cancer survival England was a key aim of the Calman–Hine Report (1995) and NHS Cancer Plan (2000). This study assesses whether changed following these policy developments by analysing trend 1-year relative 28 networks England. <h3>Methods</h3> Population-based age-standardised at 1 year is estimated for 1.4 million patients diagnosed with oesophagus, stomach, colon, lung, breast (women) or cervix during 1991–2006 followed up to 2007....