A5022799325- Advanced MRI Techniques and Applications
- Tissue Engineering and Regenerative Medicine
- Electron and X-Ray Spectroscopy Techniques
- Radiomics and Machine Learning in Medical Imaging
- Nonlinear Optical Materials Research
- 3D Printing in Biomedical Research
- Advanced Chemical Physics Studies
- Electrospun Nanofibers in Biomedical Applications
- Trace Elements in Health
- Iron Metabolism and Disorders
- Inorganic and Organometallic Chemistry
- Advanced ceramic materials synthesis
- Mosquito-borne diseases and control
- Synthesis and Properties of Aromatic Compounds
- Dental materials and restorations
- Bone Tissue Engineering Materials
- Insect Pest Control Strategies
- Conducting polymers and applications
- Molecular Junctions and Nanostructures
- Photochemistry and Electron Transfer Studies
- Advanced biosensing and bioanalysis techniques
- Advanced Neuroimaging Techniques and Applications
- Electrochemical Analysis and Applications
- Advanced Drug Delivery Systems
- Organic Chemistry Cycloaddition Reactions
University of Florida
2013-2023
Florida College
1996-2018
John Wiley & Sons (United States)
2018
Moss Landing Marine Laboratories
2018
Hudson Institute
2018
American College of Veterinary Surgeons
2018
University of Zurich
2018
Duke University
2012
Duke University Hospital
2012
Duke Medical Center
2012
The scarcity of transplant allografts for diseased organs has prompted efforts at tissue regeneration using seeded scaffolds, an approach hampered by the enormity cell types and complex architectures. Our goal was to decellularize intact in a manner that retained matrix signal differentiating pluripotent cells. We decellularized rat kidneys preserved intricate architecture them with murine embryonic stem cells antegrade through artery or retrograde ureter. Primitive precursor populated...
T he present study evaluated the potential for reestablishment of connective tissue attachment after exclusion gingival and epithelium during healing periodontal surgery in a dog model. Buccal mucoperiosteal flaps were elevated all four premolar regions two dogs. The buccal bone was reduced to approximately 25% its original level on 24 roots. Before replaced sutured, membranes adjusted cover exposed root surfaces. On eight surfaces Millipore® filters used biodegradable polylactic acid used....
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTApplications of photoelectron spectroscopy. 41. Photoelectron spectra phosphabenzene, arsabenzene, and stibabenzeneC. Batich, E. Heilbronner, V. Hornung, A. J. Ashe, D. T. Clark, U. Cobley, Kilcast, I. ScanlanCite this: Am. Chem. Soc. 1973, 95, 3, 928–930Publication Date (Print):February 1, 1973Publication History Published online1 May 2002Published inissue 1 February...
Introduction To address transplant organ shortage, a promising strategy is to decellularize kidneys in manner that the scaffold retains signals for seeded pluripotent precursor cells differentiate and recapitulate native structures: matrix-to-cell signaling followed by cell-cell cell-matrix interactions, thereby remodeling replacing original matrix. This would reduce antigenicity enable xeno-allografts.Results DAPI-labeled arterial vessels glomeruli were positive both endothelial lineage...
Feraheme, is a recently FDA-cleared superparamagnetic iron oxide nanoparticle (SPION)-based MRI contrast agent that also employed in the treatment of deficiency anemia. Feraheme nanoparticles have hydrodynamic diameter 30 nm and consist crystallites complexed with low molecular weight, semi-synthetic carbohydrate. These features are attractive for other potential biomedical applications such as magnetic fluid hyperthermia (MFH), since carboxylated polymer coating affords functionalization...
A major hurdle in most current gene therapy modalities is the ability to transduce target tissues at very high efficiencies that ultimately lead therapeutic levels of transgene expression. We have developed a novel method recombinant adeno-associated virus 2 (rAAV) delivery results increased vector transduction using microspheres reversibly conjugated rAAV vectors. hypothesize conjugation should result higher effective concentration as well longer relative exposure time cells it moves...
Magnetic nanoparticle-based gene transfection has been shown to be effective in combination with both viral vectors and non-viral agents. In these systems, therapeutic or reporter genes are attached magnetic nanoparticles which then focused the target site/cells via high-field/high-gradient magnets. The technique efficient rapid for vitro compares well cationic lipid-based reagents, producing good overall levels lower doses shorter times. spite of its potential advantages (particularly vivo...
There is a well-established link between iron overload in the brain and pathology associated with neurodegeneration variety of disorders such as Alzheimer's (AD), Parkinson's (PD) Huntington's (HD) diseases [1]. This association was first di
Background— Up to 5% of the population may have a brain aneurysm. If aneurysm ruptures, there is >50% mortality, and more than one third survivors are dependent. Brain aneurysms detected before rupture can be treated prevent rupture, or ruptured rerupture. Endovascular coiling treatment choice for some aneurysms; however, up quarter recur. The coiled that do not recur characterized by inflammatory intra-aneurysmal tissue healing; therefore, we studied biology this process, specifically...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMass spectral evidence for catenanes formed via a "Moebius-strip" approachDavid A. Ben-Efraim, C. Batich, and E. WassermanCite this: J. Am. Chem. Soc. 1970, 92, 7, 2133–2135Publication Date (Print):April 1, 1970Publication History Published online1 May 2002Published inissue 1 April 1970https://pubs.acs.org/doi/10.1021/ja00710a058https://doi.org/10.1021/ja00710a058research-articleACS PublicationsRequest reuse permissionsArticle...
Abstract A microscopic study of microplankton in two coastal lagoons the Florida Keys coincidently, and unexpectedly, revealed widespread presence high concentrations polystyrene microplastic particles. The particles were first observed second year a 2-year phytoplankton communities, with peak densities spring/summer 2019 at all ten sampling sites lagoons. Polystyrene particle reached levels up to 76,000 L −1 . ranged size from 33 190 µm, similar range microplanktonic algae (20–200 µm). Over...
A commercially available mammary implant containing a soft polyester polyurethane foam shell has been examined for possible diamine hydrolysis products. Fourier Transform Infrared (FT-IR) analysis shown ester and aromatic structures present in the intact Vigorous conditions using NaOH have produced mixture with large amounts of toluene (TDA) as determined by Gas Chromatography-Mass Spectrometry (GC/MS), GC/FT-IR. There are numerous clinical reports degradation this after implantation...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTX-ray photoelectron spectroscopy of nitroso compounds: relative ionicity the closed and open formsC. D. Batich S. DonaldCite this: J. Am. Chem. Soc. 1984, 106, 10, 2758–2761Publication Date (Print):May 1, 1984Publication History Published online1 May 2002Published inissue 1 1984https://pubs.acs.org/doi/10.1021/ja00322a004https://doi.org/10.1021/ja00322a004research-articleACS PublicationsRequest reuse permissionsArticle...
Abstract The He (I) photoelectron (PE.) spectra of bis (π‐allyl)palladium (2a) , (π‐allyl)platinum (3a) (π‐methallyl)palladium (2b) and (π‐methallyl)‐platinum (3b) have been recorded compared with the PE. (π‐allyl)nickel (1a) (π‐methallyl)nickel (1b) . By use (II) 2a, 2b 3b correlations between 1–3 it is possible to assign first seven eight transitions in In contrast previous assignments shown that band spectrum 1a corresponds ejection an electron from 7a u a pure ligand orbital. assignment...
The reflection intensities of polyaniline films (PANI) in the range 250–800 nm have been determined using a spectrometer at different potentials and pHs. effect potential pH on colors PANI mechanism redox reactions discussed.
We describe a novel technique of using fluorescent silica nanoparticles (FSNPs) to detect over-expressed folate receptors, as typical for certain malignancies (metastatic adenocarcinoma, pituitary adenoma and others). Using Stöber's method with some modification, 135 nm size FSNPs were synthesized by hydrolysis co-condensation reaction tetraethylorthosilicate (TEOS), fluorescein labeled (3-aminopropyl)triethoxysilane (APTS) water-dispersible silane reagent, (3-trihydroxysilyl)propyl...
We report the achievement of sensitive chemical and biological sensing using periodic gold nanopyramids with nanoscale sharp tips created by a simple scalable colloidal templating approach. The long-range structure nanopyramid arrays enable excitement both localized propagating surface plasmons. optical reflection detection sensitivity templated plasmon resonance sensors agree reasonably well theoretical predictions finite-difference time-domain model. have also demonstrated that specific...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEquivalence of the energy gaps .DELTA.I(1,2) and .DELTA.E(1,2) between corresponding bands in photoelectron (I) electronic absorption (E) spectra spiro[4.4]nonatetraene. Amusing consequence spiroconjugationC. Batich, E. Heilbronner, Erika Rommel, M. F. Semmelhack, J. S. FoosCite this: Am. Chem. Soc. 1974, 96, 25, 7662–7668Publication Date (Print):December 1, 1974Publication History Published online1 May 2002Published inissue 1 December...
The degrees of in vitro three-body wear resistance a hybrid, small-particle, and microfilled composite were determined after water storage for up to 24 months. hybrid was the most wear-resistant, while showed wear. no loss as result storage. small-particle decrease only when tested with silicon carbide abrasive. decreased following either soft (CaCO 3 ) or hard (SiC) For all composites, abrasive not capable causing preferential polymer matrix, observed on vivo specimens. Instead, filler...