A5045513511- Diet and metabolism studies
- Workplace Health and Well-being
- Physical Activity and Health
- Obesity, Physical Activity, Diet
- Healthcare professionals’ stress and burnout
- Employment and Welfare Studies
- Diabetes Treatment and Management
- Regional Development and Management Studies
- Pharmacology and Obesity Treatment
- Obesity and Health Practices
- Bariatric Surgery and Outcomes
- Nutritional Studies and Diet
- Job Satisfaction and Organizational Behavior
- Occupational Health and Safety Research
- Innovations in Medical Education
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Diabetes Management and Research
- Gestational Diabetes Research and Management
- Cardiovascular and exercise physiology
- High Altitude and Hypoxia
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cardiovascular and Diving-Related Complications
- Children's Physical and Motor Development
- Nutrition and Health in Aging
- Diabetes and associated disorders
Oxford Centre for Diabetes, Endocrinology and Metabolism
2021-2025
University of Cambridge
2009-2024
University of Oxford
2021-2024
Wellcome/MRC Institute of Metabolic Science
2019-2024
MRC Epidemiology Unit
2014-2023
Cambridge University Hospitals NHS Foundation Trust
2018-2023
Addenbrooke's Hospital
2013-2022
Oxford University Hospitals NHS Trust
2022
Wellcome Trust
2019-2020
Papworth Hospital NHS Foundation Trust
2019
Background: To assess the incidence of dysglycaemia and metabolic syndrome factors associated with them 5 months postpartum in women gestational diabetes mellitus (GDM) their last pregnancy. Methods: We conducted an observational prospective cohort study 558 previous GDM who attended a 5-month follow-up clinic. Backward elimination was performed to select significant for multivariable logistic regression model. Dysglycaemia (prediabetes type 2 (T2D)) were used as outcomes separate models....
Abstract Title. Work‐related stress, education and work ability among hospital nurses. Aim. This paper is a report of study conducted to determine which occupational stressors are present in nurses’ working environment; describe compare stress between two educational groups nurses; estimate what extent predict ability; if level predicts ability. Background. Nurses’ adversely affects their health nursing quality. Higher has been shown have positive effects on the preservation good Method. A...
To examine the validity of Recent Physical Activity Questionnaire (RPAQ) which assesses physical activity (PA) in 4 domains (leisure, work, commuting, home) during past month.580 men and 1343 women from 10 European countries attended 2 visits at PA energy expenditure (PAEE), time moderate-to-vigorous (MVPA) sedentary were measured using individually-calibrated combined heart-rate movement sensing. At second visit, RPAQ was administered electronically. Validity assessed agreement...
Aim To synthesise a selection of UK medical students’ and doctors’ views surrounding nutrition in education practice. Methods Information was gathered from surveys students doctors identified between 2015 2018 an evaluation teaching single school. Comparative analysis the findings undertaken to answer three questions: perceived importance practice, adequacy training, confidence current knowledge skills. Results We pooled five heterogeneous sources information, representing 853 participants....
The objective of this study is to examine the independent associations time spent in moderate-to-vigorous physical activity (MVPA) and sedentary (SED-time), with total abdominal body fat (BF), bidirectionality these adults at high risk type 2 diabetes. We measured MVPA (min per day) SED-time (h by accelerometry, indices (body weight, mass (FM), BF% FM index) BF (waist circumference (WC)) using standard procedures 231 (41.3±6.4 years) parental history diabetes (ProActive UK) baseline, 1-year...
In a single general practice (GP) surgery in England, there was an eightfold increase the prevalence of type 2 diabetes (T2D) three decades with 57 cases and 472 recorded 1987 2018, respectively. This mirrors growing burden T2D on health populations round world along healthcare funding provision more broadly. Emerging evidence suggests beneficial effects carbohydrate-restricted diets glycaemic control T2D, but its impact 'real-world' primary care setting has not been fully evaluated.Advice...
Detailed assessment of physical activity (PA) in older adults is required to comprehensively describe habitual PA-levels this growing population segment. Current evidence predominantly based on self-report.We examined PA and sedentary behaviour a nationally representative sample British people aged 60-64, using individually-calibrated combined heart-rate movement sensing validated questionnaire (EPAQ2), the socio-demographic behavioural factors that may explain between-individual variation...
Physical activity is associated with decreased risk of coronary heart disease (CHD). The specific physical types that provide beneficial effects in an older population remain unclear. We assessed the association total activity, walking, cycling, domestic work, sports, and gardening CHD by using Cox proportional hazard models among 5,901 participants aged >55 (median age, 67) years from prospective population-based Rotterdam Study, enrolled between 1997 2001. Activities were categorized into...
Methods to classify activity types are often evaluated with an experimental protocol involving prescribed physical activities under confined (laboratory) conditions, which may not reflect real-life conditions. The present study aims evaluate how design impact on classifier performance in real life. Twenty-eight healthy participants (21-53 yr) were asked wear nine triaxial accelerometers while performing 58 selected simulate For each sensor location, logistic classifiers trained subsets of up...
Abstract Aims To establish which components of energy balance mediate the clinically significant weight loss demonstrated with use cotadutide, a glucagon‐like peptide‐1 (GLP‐1)/glucagon receptor dual agonist, in early‐phase studies. Materials and Methods We conducted phase 2a, single‐centre, randomized, placebo‐controlled trial overweight obese adults type 2 diabetes. Following 16‐day single‐blind placebo run‐in, participants were randomized 2:1 to double‐blind 42‐day subcutaneous treatment...
Objectives To compare physical activity (PA) subcomponents from EPIC Physical Activity Questionnaire (EPAQ2) and combined heart rate movement sensing in older adults. Methods Participants aged 60–64y the MRC National Survey of Health Development Great Britain completed EPAQ2, which assesses self-report PA 4 domains (leisure time, occupation, transportation domestic life) during past year wore a sensor for 5 consecutive days. Estimates energy expenditure (PAEE), sedentary behaviour, light...
Objectives Updated knowledge about perioperative myocardial ischaemia (MI) after coronary artery bypass grafting (CABG) and treatment of acute graft failure is needed. We analysed main factors associated with MI effects immediate angiography-based strategy on patient outcome. Methods Among 1119 consecutive patients disease who underwent isolated CABG between January 2011 December 2015, 43 (3.8%) urgent angiography due to suspected MI. All the data were prospectively collected retrospectively...
ABSTRACT Objective To estimate dose-response associations between non-occupational physical activity and multiple chronic disease outcomes in the general adult population. Eligibility criteria Prospective cohort studies with (a) population samples >10,000 adults, (b) ≥3 exposure categories, (c) risk measures confidence intervals for all-cause mortality, total cardiovascular disease, coronary heart stroke, failure, cancer, site-specific cancers (head neck, myeloid leukemia, myeloma,...
Diabetes and hyperglycaemia are associated with increased morbidity large healthcare economic costs.1 Glucocorticoid-induced diabetes common. Glucocorticoids used widely to treat people inflammatory autoimmune conditions,2 malignancies3 in hospitalised patients COVID-19.4 In the United Kingdom (UK), among patients, prevalence of glucocorticoid use is 10% all patients5 25–40% those diabetes.6 This adverse metabolic outcomes including impaired glycaemic control7 can manifest as a new-onset...