A5010241373- vaccines and immunoinformatics approaches
- Influenza Virus Research Studies
- Immunotherapy and Immune Responses
- Child Nutrition and Water Access
- Monoclonal and Polyclonal Antibodies Research
- Animal Virus Infections Studies
- Hepatitis B Virus Studies
- Obesity, Physical Activity, Diet
- Fatty Acid Research and Health
- Enzyme Catalysis and Immobilization
- Phytase and its Applications
- Microbial Metabolic Engineering and Bioproduction
- Transgenic Plants and Applications
- Child Nutrition and Feeding Issues
- Proteins in Food Systems
- Nanoparticles: synthesis and applications
- Retinoids in leukemia and cellular processes
- Ginger and Zingiberaceae research
- Fibroblast Growth Factor Research
- Medicinal Plants and Neuroprotection
- Enzyme Production and Characterization
- Iron Metabolism and Disorders
- Antioxidant Activity and Oxidative Stress
- SARS-CoV-2 and COVID-19 Research
- Cell Adhesion Molecules Research
Jaipur National University
2023-2024
Thapar Institute of Engineering & Technology
2014-2020
Shreemati Nathibai Damodar Thackersey Women's University
2014-2015
Fred Hutch Cancer Center
2011
We are reporting qualitative and quantitative changes of the extracellular matrix (ECM) associated receptor proteomes, occurring during transition from liver fibrosis steatohepatitis to hepatocellular carcinoma (HCC). compared two mouse models relevant human HCC: PDGFC transgenic (Tg) Pten null mice, disease progression HCC. Using mass spectrometry, we identified in both proteins for 26 collagen-encoding genes, providing first evidence expression at protein level 16 collagens. also...
Infant and child feeding index (ICFI) an age-specific index, can be used to assess practices. We the ICFI practices for urban slum children association between nutritional status. 446 aged 6 24 months from slums of Mumbai, India were studied. 24-hour diet recall study dietary diversity a food frequency questionnaire consumption groups during preceding week. was computed using five components, namely, breastfeeding, use bottle, score (DDS), group (FGFS) scores (FFS). Weight, height Mid-Upper...
Researchers have shown substantial interest in bismuth oxide/reduced graphene oxide (Bi
The concept of peptide-based vaccines against cancer has made noteworthy progress. Metadherin (MTDH) overexpression and its role in the development diverse cancers make it an attractive target for immunotherapy. In current study, six different T cell epitope prediction tools were run to identify MTDH peptides with multiple immunogenic regions. Further, molecular docking was performed assess HLA-peptide binding interactions. Nine eleven fragments containing CD8 (+) CD4 T-cell epitopes,...
Cell mediated immune response plays a key role in combating viral infection and thus identification of new vaccine targets manifesting T cell may serve as an ideal approach for influenza vaccine. The present study involves the application immunoinformatics-based consensus epitope prediction (three tools each CD4+ CD8+ epitopes) molecular docking to identify peptide sequences containing epitopes using conserved from all Matrix 1 protein H1N1 virus available until April 2015. Three peptides...
Pandemic threats of the H1N1 influenza virus have drawn attention to developing a universal vaccine against circulating and future strains this virus. An immunoinformatics study was conducted identify conserved peptides containing CD4+ CD8+ T-cell epitopes from all hemagglutinin (HA) neuraminidase (NA) protein sequences available until February 2013 cover seasonal as well pandemic In present study, six different prediction programs were used in order define epitopes. Five HA NA obtained that...
Influenza vaccine development is considered to be complicated and challenging. Constantly evolving influenza viruses require continuous global monitoring reformulation of the strains. Peptides that are conserved among different strains subtypes A virus strongly attractive targets for cross protective vaccines stimulate cellular responses. In this study, three highly (>90%) matrix 1 peptides contain multiple T cell epitopes, ILGFVFTLTVPSERGLQRRRF (PM 1), LIRHENRMVLASTTAKA 2) LQAYQKRMGVQMQR...
Background Adequate folate intake and levels are advisable throughout life but of particular importance during adolescence, a period rapid growth. However, insufficiency in economically deprived Indian adolescents is understudied. Objective This cross-sectional study examined the prevalence deficiency adequacy 224 tribal (10 to 17 years age). The secondary aim was association between anemia status status. Methods Radioimmunoassay, multiple-pass 24-hour dietary recall, HemoCue were used...
Serum alpha-tocopherol, retinol, and malondialdehyde concentrations were measured at 7(th) month of pregnancy in 122 women from low socio-economic background. Maternal anthropometric measurements, 24-hour nutrient intakes, outcome recorded. One-third (34.3 %) mothers had birth weight babies 10 % delivered preterm. diets inadequate all the nutrients, most limiting being vitamin A. Three-fourths intakes less than 25 Indian recommended daily intake (RDI) 600 microg retinol equivalents/day....
Gram-negative, rod-shaped Pseudomonas putida bacteria may be found in a variety of biological environments. This ubiquity can attributed to its extraordinarily adaptable metabolism, ability endure physicochemical stress, and propensity survive unfavorable conditions. These traits have led an increase interest microorganisms for industrial usage, also associated with studying has advanced quickly recent years. Strong motivators this regard include use inexpensive waste streams sustainable...