A5101470431- Liver Disease Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- Breast Cancer Treatment Studies
- Peroxisome Proliferator-Activated Receptors
- Sinusitis and nasal conditions
- Pregnancy and preeclampsia studies
- Otolaryngology and Infectious Diseases
- Nuclear Receptors and Signaling
- Cardiovascular Issues in Pregnancy
- Renal Diseases and Glomerulopathies
- Breast Implant and Reconstruction
- Pharmacological Effects of Natural Compounds
- Macrophage Migration Inhibitory Factor
- Bone health and osteoporosis research
- Phagocytosis and Immune Regulation
- Pancreatitis Pathology and Treatment
- FOXO transcription factor regulation
- Nonmelanoma Skin Cancer Studies
- Cancer-related molecular mechanisms research
- Cancer Cells and Metastasis
- Infectious Diseases and Tuberculosis
- Drug-Induced Hepatotoxicity and Protection
- Bone Metabolism and Diseases
Second Affiliated Hospital of Xi'an Jiaotong University
2023-2024
Leiden University Medical Center
2023
First Affiliated Hospital of Xi'an Jiaotong University
2005-2022
Third Xiangya Hospital
2016
Central South University
2016
Dongfeng Motor Group (China)
2006
First Hospital of Xi'an
2005
Aim: As one of the most widely used anti-diabetic drug for type II diabetes, metformin has been shown to exhibit anti-cancer activity in recent years. Epidermal growth factor (EGF) and its receptor, EGFR, play important roles cancer metastasis various tumors, including breast cancer. Epithelial-mesenchymal transition (EMT) is a critical process invasion metastasis. In this study, we use EGF as metastatic inducer investigate effect on cell migration, EMT. Methods: Human MCF-7 cells were...
Insufficient immune tolerance during pregnancy is associated with pathological conditions such as preeclampsia (PE). Soluble fms-like tyrosine kinase-1 (sFLT1), which exerts a role in the late stage of PE, has shown its beneficial anti-inflammatory effects inflammation-associated diseases. Macrophage migration inhibitory factor (MIF) was reported to upregulate sFLT1 production experimental congenital diaphragmatic hernia. However, placental expression early uncomplicated and whether MIF can...
COVID-19-associated acute kidney injury (COVID-19 AKI) is an independent risk factor for in-hospital mortality and has the potential to progress chronic disease. Prunella vulgaris L ., a traditional Chinese herb that been used treatment of variety diseases centuries, could have treat this complication. In study, we studied protective role in COVID-19 AKI explored its specific mechanisms applied by network pharmacology bioinformatics methods. The combination protein-protein interaction Gene...
Objective The objective of this study is to explore the efficacy and safety mizoribine (MZR) in treating nephrotic syndrome patients afflicted with hepatitis B virus (HBV). Methods present included 36 accompanied HBV infection. A draft MZR (150-200 mg/d), methylprednisolone (0.6-0.8 mg/kg·d), entecavir (0.5 mg/d) was administered over 24 weeks. serum albumin (AlB), 24-h urine protein (24-U-TP), liver renal functions, HBV-DNA were quantified before at 2, 4, 8, 12, 16, 20, weeks after...