- Fatigue and fracture mechanics
- Structural Integrity and Reliability Analysis
- Numerical methods in engineering
- Material Properties and Failure Mechanisms
- Structural Health Monitoring Techniques
- Welding Techniques and Residual Stresses
- Ultrasonics and Acoustic Wave Propagation
- Engineering Structural Analysis Methods
- Mechanical stress and fatigue analysis
- High-Velocity Impact and Material Behavior
- Fluid Dynamics Simulations and Interactions
- Protease and Inhibitor Mechanisms
- Structural Load-Bearing Analysis
- Mechanical Behavior of Composites
- Structural Behavior of Reinforced Concrete
- Non-Destructive Testing Techniques
- Computational Geometry and Mesh Generation
- Concrete Corrosion and Durability
- Corrosion Behavior and Inhibition
- Ship Hydrodynamics and Maneuverability
- Engineering Applied Research
- Metal Forming Simulation Techniques
- Contact Mechanics and Variational Inequalities
- Historical and Literary Studies
- Hydrogen embrittlement and corrosion behaviors in metals
Osaka Dental University
2021-2024
Yokohama National University
2008-2019
Teijin (Japan)
1987-2007
Fujitsu (Japan)
1990-2003
Marymount University
1991-2001
Kobe University
2000
Jichi Medical University
1987-1989
Central Research Laboratories (United Kingdom)
1988
Tokyo Medical and Dental University
1988
The University of Tokyo
1974-1987
ABSTRACT Tissue and urokinase-type plasminogen activators are serine proteases with highly restricted specificity, their best characterised role being to release the broad specificity protease plasmin from inactive plasminogen. It has frequently been suggested that these, similar proteases, involved in axonal growth tissue remodelling associated neural development. To help define what this might be, we have studied expression of developing rat nervous tissue. Urokinase-type activator mRNA is...
The expression of tissue- and urokinase-type plasminogen activators has been studied in developing cerebellum, hippocampus, cerebral cortex, olfactory bulb mucosa the rat by situ hybridization. All identifiable neurons express urokinase mRNA from an early stage their development, this appears to coincide with onset axogenesis. For cerebellar granule cells, both axonal growth are initiated before they migrate external layer; for majority neocortical neurons, however, processes commenced after...
We have isolated overlapping phage genomic clones covering an area of 26 kilobases that encodes the human alpha 2-plasmin inhibitor. The inhibitor gene contains 10 exons and 9 introns distributed over approximately 16 DNA. To our knowledge, number is highest yet reported for a member serine protease (serpin) superfamily. All are located in 5'-half corresponding mRNA. 5'-untranslated region leader sequence interrupted by 3 totaling equal to 6 kilobases. A "TATA box" 17 nucleotides upstream...
We developed a new porous scaffold made from synthetic polymer, poly(DL-lactide-co-glycolide) (PLG), and evaluated its use in the repair of cartilage. Osteochondral defects on femoral trochlear rabbits were treated by transplantation PLG scaffold, examined histologically compared with an untreated control group. Fibrous tissue was initially organised arcade array poor cellularity at articular surface scaffold. The regenerated to cartilage surface. In subchondral area, bone formed absorbed....