- Advanced MRI Techniques and Applications
- Advanced Neuroimaging Techniques and Applications
- Elasticity and Material Modeling
- Electric Motor Design and Analysis
- Ultrasound Imaging and Elastography
- Sparse and Compressive Sensing Techniques
- Medical Imaging Techniques and Applications
- Fetal and Pediatric Neurological Disorders
- Magnetic Properties and Applications
- Magnetic Bearings and Levitation Dynamics
- Epilepsy research and treatment
- Advanced Aircraft Design and Technologies
- Spacecraft and Cryogenic Technologies
- Functional Brain Connectivity Studies
- Cerebrospinal fluid and hydrocephalus
- Aerodynamics and Acoustics in Jet Flows
- Liver Disease Diagnosis and Treatment
- Computational Fluid Dynamics and Aerodynamics
- Magnetic Field Sensors Techniques
- Medical Image Segmentation Techniques
- Traumatic Brain Injury and Neurovascular Disturbances
- Image and Signal Denoising Methods
- Cardiac Imaging and Diagnostics
- Atomic and Subatomic Physics Research
- Traumatic Brain Injury Research
University of Illinois Urbana-Champaign
2012-2025
Glenn Research Center
2019-2024
Carle Foundation Hospital
2020-2024
The University of Texas Southwestern Medical Center
2023
Imaging Center
2022-2023
Leiden University Medical Center
2023
Bioengineering Center
2023
Clinical Research Institute
2022
Tennessee Technological University
2014
Virginia Commonwealth University
2007
Viscoelastic mechanical properties of the brain assessed with magnetic resonance elastography (MRE) are sensitive measures microstructural tissue health in neurodegenerative conditions. Recent efforts have targeted measurements localized to specific neuroanatomical regions differentially affected disease. In this work, we present a method for measuring viscoelasticity subcortical gray matter (SGM) structures, including amygdala, hippocampus, caudate, putamen, pallidum, and thalamus. The is...
Objective: To develop a novel multi-TE MR spectroscopic imaging (MRSI) approach to enable label-free, simultaneous, high-resolution mapping of several molecules and their biophysical parameters in the brain. Methods: The proposed method uniquely integrated an augmented molecular-component-specific subspace model for <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><tex-math notation="LaTeX">$^{1}$</tex-math></inline-formula> H-MRSI...
We present a new method that integrates subspace modeling and pre-learned spatiotemporal denoiser for reconstruction from highly noisy magnetic resonance spectroscopic imaging (MRSI) data. The model imposes an explicit low-dimensional representation of the high-dimensional spatiospectral functions interest noise reduction, while serves as complementary prior to constrain reconstruction. A self-supervised learning strategy was proposed train can distinguish spatio-temporally correlated...
Electric aircraft propulsion is a growing research area that looks into achieving through fully electric or hybrid systems while low emissions. The system-level benefit gained by different and hybrid-electric schemes depends heavily on the performance of components in drive-train, including motor, gear box, motor drive, protection systems, as well thermal management system. When comparing topologies, it important to understand measures such efficiency specific power drive system level. Many...
OBJECTIVE In the United States, more than 1 million sport-related concussions afflict children annually, with many cases undetected or unreported. The Sport Concussion Assessment Tool (SCAT) is widely used to detect in high school, collegiate, and professional sports. objective of this study was establish baseline values for SCAT version 5 (SCAT5) school athletes. METHODS Baseline SCAT5 evaluations were conducted students (ages 14–19 years) from 19 schools central Illinois who participating...
Abstract Purpose To develop and evaluate a novel method for computationally efficient reconstruction from noisy MR spectroscopic imaging (MRSI) data. Methods The proposed features (a) strategy that jointly learns nonlinear low‐dimensional representation of high‐dimensional signals neural‐network‐based projector to recover the embeddings noisy/limited data; (b) formulation integrates forward encoding model, regularizer exploiting learned representation, complementary spatial constraint; (c)...
BACKGROUND AND OBJECTIVES: Over a million sport-related concussions (SRC) affect children annually in the United States, posing significant public health concern. Limited data exist on premorbid risk factors and injury characteristics of SRCs high school athletes. This study aims to understand acute SRC describe METHODS: Athletes (aged 14-19 years) from 19 central Illinois schools participating school-sponsored sports 2009 2023 were included. Sports Concussion Assessment Tool evaluations...
Mesial temporal lobe epilepsy (MTLE) is the most common form of refractory epilepsy. Common imaging biomarkers are often not sensitive enough to identify MTLE sufficiently early facilitate greatest benefit from surgical or pharmacological intervention. The objective this work establish hippocampal stiffness measured with magnetic resonance elastography (MRE) as a biomarker for MTLE; we hypothesized that epileptogenic hippocampus in stiffer than non-epileptogenic hippocampus. MRE was used...
NASA's all-electric X-57 airplane will utilize 14 electric motors, of which 12 are exclusively for lift augmentation during takeoff and landing. This report covers the design development process taken to create an open reference model representative high augmenting motors. A combined worst case scenario was used as point, represents simultaneously occurring aspects thermal, static stress, electromagnetic, rotor dynamic conditions. work highlights tightly coupled nature aerospace motor...
Abstract It is now established that the primary microseism, secondary microseisms, and hum are three main components of seismic noise in frequency band from about 0.003 Hz to 1.0 Hz. Monthly averages dominated by these signals noise. There are, however, some temporary additional same band, such as tropical cyclones (hurricanes typhoons) ocean on land, stormquakes, weather bombs, tornadoes, wind-related atmospheric pressure loading. We review effects, lasting only a few hours week but...
Abstract Purpose To develop and validate a noninvasive imaging technique for accurately assessing very slow CSF flow within shunt tubes in pediatric patients with hydrocephalus, aiming to identify obstructions that might impede drainage. Theory Methods A simulation of enhancement signal intensity (shunt‐FENSI) is used establish the relationship between change rate. The quantification data involves normalization, curve fitting, calibration match simulated data. Additionally, phase sweep...
Epilepsy is a prevalent and serious neurological condition which impacts millions of people worldwide. Stereoelectroencephalography (sEEG) used in cases drug resistant epilepsy to aid surgical resection planning due its high spatial resolution ability visualize seizure onset zones. For accurate localization the focus, sEEG studies combine pre-implantation magnetic resonance imaging, post-implant computed tomography electrodes, temporally recorded electrophysiological data. Many tools exist...
CrossFit™ is a novel training modality but empirical support of its effectiveness lacking (1). The purpose the current study was to: 1) examine effect on health-related physical fitness, and 2) to compare effects against matched participants in traditional program. Pre- post-assessments aerobic capacity, body composition, upper-body muscular endurance, power, hamstring flexibility were conducted. improved capacity (6%) endurance (22%) with mean change differing significantly from group (p = .004).
Temporally developing turbulent planar free shear layers with Mach numbers M = 1.5, 2.5, and 3.5 are directly simulated to provide a geometrically simplified model of the generation peculiar sound, known as ‘crackle’. Sound-field pressure skewness for 2.5 cases exceed Sk(p ′) > 0.4, which has been correlated perception crackle. Statistics related wave angle density indicate nonlinear interactions in very near acoustic field these same cases. Results show both merging multiple waves...
View Video Presentation: https://doi.org/10.2514/6.2021-3276.vid NASA's High Efficiency Megawatt Motor (HEMM) is being developed to achieve the performance needed by single aisle class electrified aircraft. It a 1.4 MW electric machine designed as generator for STARC-ABL concept vehicle. has objectives of greater than 16 kW/kg electromagnetic specific power and efficiency 98%. The key enabling technology HEMM's high metrics superconducting rotor cooled an integrated cryocooler. cryocooler...
This paper discusses the manufacturing process and qualification procedures of a slotless stator for 1-MW high-speed permanent magnet synchronous machine. The motor, targeted to reach 13 kW/kg, assembled with form-wound air-core armature winding which utilizes litz wire as conductor. A prototype is being developed full-power test will be done in near future. insulation, mechanical thermal are discussed detail. Results showed that tolerances significantly affect machine performances. Various...