A5022480549- Cardiovascular and exercise physiology
- Cardiomyopathy and Myosin Studies
- Heart Rate Variability and Autonomic Control
- Non-Invasive Vital Sign Monitoring
- Congenital Heart Disease Studies
- Blood Pressure and Hypertension Studies
- Cardiac Imaging and Diagnostics
- Cardiovascular Effects of Exercise
- Cardiovascular Function and Risk Factors
Newcastle upon Tyne Hospitals NHS Foundation Trust
2023-2024
Clinical Research Institute
2024
University of Newcastle Australia
2024
Newcastle University
2023-2024
Imam Abdulrahman Bin Faisal University
2021-2024
Abstract Non‐invasive technologies have become popular for the clinical evaluation of cardiac function. The present study evaluated hemodynamic response to cardiopulmonary exercise stress testing using bioreactance technology in patients with hypertrophic cardiomyopathy. included 29 HCM (age 55 ± 15 years; 28% female) and 12 age (55 14 years), gender matched (25% healthy controls. All participants underwent maximal graded simultaneous non‐invasive gas exchange. At rest, demonstrated...
Abstract Funding Acknowledgements Type of funding sources: None. Objective Cardiovascular autonomic function, represented by heart rate variability (HRV) is a simple, non-invasive measure used to determine alteration sympathetic and parasympathetic control. The aim the present study was firstly evaluate effect age gender on HRV measures, secondly relationship between measures functional capacity in healthy individuals Methods This retrospective, single centre, cross-sectional, observational...
Background A limited number of studies have investigated the effects lifestyle interventions in hypertrophic cardiomyopathy (HCM). This study evaluated effect a novel intervention incorporating physical activity (PA) and dietary nitrate supplementation on heart rate variability (HRV) haemodynamic measures HCM.
<h3>Introduction</h3> Engagement in regular physical activity reduces symptom burden and improves quality of life individuals with hypertrophic cardiomyopathy (HCM) those living heart failure (HF). This study evaluated the activity, inactivity sleep HCM versus HF. <h3>Methods</h3> Twenty-one (52±15 years old, body mass index (BMI) 29 (26–31) kg/m2) eighteen stable chronic HF reduced ejection fraction (68±7 BMI: 27 (25–31) kg/m2, left ventricular fraction: 35 (30–35) %) completed 7-day...
Background: Hypertrophic cardiomyopathy (HCM) is a global heart disease with great variability in severity, which can lead to significant impairment of exercise capacity. In healthy populations, oxygen consumption related cardiac output and arteriovenous difference. We sought determine the relationship between hemodynamics (cardiac stroke volume) HCM compared controls during maximal stress testing. Aims: To evaluate associations trajectories hemodynamic function controls. Methods: Twenty...
Heart rate variability (HRV) is a measure of cardiac autonomic function. This study: (1) evaluated the differences in HRV and haemodynamic function between individuals with hypertrophic cardiomyopathy (HCM) healthy controls, (2) determined relationship variables HCM.Twenty-eight HCM (n = 7, females; age 54 ± 15 years; body mass index: 29 5 kg/m2 ) 28 matched 7 16 completed 5-min measurements under resting (supine) conditions using bioimpedance technology. Frequency domain measures (absolute...
Abstract Funding Acknowledgements Type of funding sources: Public grant(s) – EU funding. Main source(s): This project has received from the European Union’s Horizon 2020 Research and Innovation Programme under Grant Agreement no. 777204. Background Autonomic nervous system may play an important role in pathophysiology hypertrophic cardiomyopathy (HCM). Lifestyle interventions have been shown to improve signs symptoms individuals with heart failure. Purpose To evaluate effect a novel...
Abstract Physical activity presents an important cornerstone in the management and care of individuals with hypertrophic cardiomyopathy (HCM). Twenty-one HCM (age: 52±15 years old, body mass index (BMI): 30±7 kg/m2) completed 7-day monitoring using wrist-worn triaxial accelerometers (GENEActiv, ActivInsights Ltd, UK) were compared to age sex-matched healthy controls 51±14 BMI: 25±4 kg/m2). For HCM, clinical parameters (left atrial diameter volume, peak oxygen consumption, NTproBNP Minnesota...