The ubiquitin-proteasome pathway is primarily responsible for myofibrillar protein degradation during hindlimb unweighting (HU). β-Adrenergic agonists such as clenbuterol (CB) induce muscle hypertrophy and attenuate atrophy due to disuse or inactivity. However, the molecular mechanism by which CB exerts these effects remains poorly understood. aims of this study were investigate whether attenuates HU-induced through an inhibition insulin-like growth factor I (IGF-I) mediates inhibition. Rats...

Purpose To estimate the exchange rate of creatine (Cr) CEST and to evaluate pH sensitivity guanidinium (Guan) in mouse brain. Methods Polynomial Lorentzian line‐shape fitting (PLOF) were implemented extract amine, amide, Guan signals from brain Z‐spectrum at 11.7T. Wild‐type (WT) knockout mice with guanidinoacetate N‐methyltransferase deficiency (GAMT −/− ) that have low Cr phosphocreatine (PCr) concentrations used CrCEST signal. quantify rate, a two‐step Bloch‐McConnell (BM) was fit...

Chatbots can change health behaviors by generating conversations about health. A well-designed health-related chatbot encourage people to be physically active creating a therapeutic relationship. This study aimed develop and evaluate the feasibility usability of chatbot-based physical activity self-management application promote among community-dwelling older adults. The was designed based on five stages ADDIE model (analysis, design, development, implementation, evaluation). mobile (app)...

Background: Postmenopausal women may be susceptible to unhealthy eating and physical activity behaviors increased cardiometabolic risk. Objective: This study examined the effectiveness of a community-based lifestyle behavioral intervention in modifying behaviors, their determinants, risk factors community-dwelling postmenopausal women. Methods: A 2-arm, parallel-group, randomized controlled trial was conducted with 46 recruited from churches universities Seoul, South Korea. Participants were...

Purpose To extract guanidinium (Guan) and amide CEST on the human brain at 3 T MRI with high spectral resolution (HSR) combined polynomial Lorentzian line‐shape fitting (PLOF). Methods Continuous wave (cw) turbo spin‐echo (TSE) was implemented to obtain optimum saturation parameters. Both Guan peaks were extracted quantified using PLOF method. The NMR spectra egg white phantoms acquired reveal range contributions GuanCEST. Two types of approaches, including cw gradient‐ (cwGRASE) steady...

Purpose: Handgrip strength is an indicator of overall muscle and has been associated with increased risk cardiovascular disease. Evidence suggests that menopause a factor for disease in women, decreases progressively after menopause. Despite the prognostic importance decline among postmenopausal evidence their association limited. This study aimed to investigate relationship between handgrip postmenopausal, middle-aged Korean women. Patients Methods: Using pooled cohort equations, we...

This study aimed to identify the actual and perceived features of neighborhood environments linked health behaviors obesity status in vulnerable children by using geographic information systems, walking surveys, focus group interviews. The participants were 126 registered at community child centers 10 mothers participants. Increased availability fast food outlets convenience stores was significantly positively associated with sugar-sweetened beverage consumption inversely physical activity....

Purpose: This study aimed to explore ecological factors and strategies for childhood obesity prevention targeting vulnerable children using a community-based participatory research (CBPR) methodology. Methods: The CBPR was conducted by following basic process steps. Participants were 12 community stakeholders such as child center directors (n=4), children’s mothers (n=3), health officials (n=2), lay advisors (n=4); they purposively sampled from K municipal county in Seoul, South Korea....

This study explores the levels of COVID-19 knowledge, risk perception, and preventive behavior practice in Seoul, to determine whether knowledge perception are significantly associated with full adoption behaviors, for delivery a customized public campaign Seoul's citizens. A total 3000 Seoul residents participated this through an online questionnaire survey. They had mean score 84.6 (range: 0-100 points) 4.2 1-7 perception. Of participants, 33.4% practiced all three behaviors: hand hygiene,...

Introduction: Researchers explored the meanings of “eating” for obese children from socioeconomically disadvantaged families and identified multilevel factors strategies their healthy eating based on ecological perspectives. Methodology: Grounded a qualitative research design, focus group interviews were conducted with each key stakeholders: children, mothers, social workers public welfare systems in South Korea. Results: “Eating” “healthy eating” defined as “fulfilling deprivations”...

Outreach programs are considered a key strategy for providing services to underserved populations and play central role in delivering health-care services. To address this challenge, knowledge relevant global health outreach has recently been expanded. The aims of study were analyze the structure understand trends aspects over time across regions using text network analysis with NetMiner 4.0. Data by frequency, region showed that keywords such as patient, care, service community found be...

본 연구는 제주도내 장애인생활체육지도자의 직무역할을 어떻게 인지하고 수행하는지, 그 과정에서 제주도라는 지역적 특성이 미치는 영향에 대해 탐색하는 것을 목적으로 하였다. 연구 참여자는 장애인체육회에 근무하고 있는 장애인생활체육지도자 총 7명으로 구성하였다. 이들을 대상으로 사전에 직무역할과 근무형태에 파악하기 위해 문헌조사를 통해 자료수집을 하였으며 참여자의 현장 경험을 도출하기 반구조화된 질문지를 작성하여 심층면담을 실시 참여 관찰을 장애인생활체육지도자들의 현장을 노트에 작성하였다. 면담 내용과 담은 노트를 참고하여 귀납적 내용분석법을 사용하여 개념과 맥락을 비교하고 범주화하여 분석하였다. 연구의 결론은 다음과 같다. 첫째, 장애인생활체육지도자들은 역할로 2개의 핵심주제와 6개의 하위주제가 도출되었다. 다양한 참여기회 제공자로서 경험 제공, 개별화 체육수업을 통한 통합체육으로의 연계, 생활체육 참여를 시작으로 전문체육으로의 연계하는 역할을 언급하였으며, 움직임 자체의 의미...

We aim to use three different approaches estimate the exchange rate of creatine (Cr) CEST, i.e., pure CrCEST line-shape, B1-dependent CrCEST, and pH response with B1 values. The signal extracted using wild type GAMT-/- mice low Cr PCr concentrations; in brain cells altered by hypercapnia demonstrate sensitivity GuanCEST; a two-step Bloch-McConnell fitting implemented quantify rates. vivo was found slow (~260-350 s-1). is major contribution opposite pH-dependence GuanCEST under B1.

Background/Objectives: Hand grip strength (HGS) reflects muscle and is an important indicator of sarcopenia. There a gap in the research regarding determinants relative HGS that take sex differences into account. Therefore, this study aimed to evaluate association between physical, behavioral, psychological factors menopausal women from South Korea. Methods: This used data obtained 7th National Health Nutrition Examination Survey (2016-2018), which had complex, stratified, multistage sample...

Objective: There is scarce evidence revealing an association between job stress and cardiometabolic lifestyle modification behaviors among workers. Methods: A cross-sectional, correlation study was conducted workers in high-risk low-risk workplaces by work characteristics. Results: Workers had significantly higher levels than workplaces. Higher associated with lower (β = −0.14, P .001). This significant evident only for total −0.16, .001), including demand .005) insecurity −0.11, .026)....

이 논문의 주장은 두 가지이다. 시 해석의 개별적 자율성과 함께 그 보편성이 유지되기 위한 방법은 무엇인가. 또 어려운 시는 학교 교육에서 어떻게 수용되어야 하는가. 이것은 작품 이해의 보편성을 논리적 근거를 확보하는 일이며 다른 한편으로 이해를 자료의 실증성과 관련되는 일이다. 이에 대해서 이해와 관련된 교육은 퍼스의 기호학을 참고할 필요가 있으며, 현행 교육과정에서 요구되는 쉬운 작품의 작품에 대한 적극적인 수용으로 넓혀질 있다는 사실을 본 논문은 확인하였다.

This study identified predictors of appointment adherence and examined its impacts on improvements in metabolic risk factors a free city-wide cardiovascular disease prevention program Seoul, South Korea. Data 8251 citizens with syndrome were used. Appointment adherers defined as having 70% or higher rates, that is, 3 more visits. Of the citizens, 17.6% adherers. significantly likely to be older, low-income earners, nonsmokers, nonobese than nonadherers. Moreover, adherers, compared...

Background Patients with deviated nose frequently present concomitant nasal bone as well septal deviation. Many surgical methods have been developed to address such deviation, along various osteotomy techniques correct The authors performed medial and paramedian osteotomies treat mild hump, utilized the acquired wedge shaped graft achieve reposition bony vault correction. Methods From October 2014 through June 2015, 10 patients deviation that showed sufficient lateral wall angle but dorsum...

Metabolic syndrome (MetS) is a significant risk factor for cardiovascular disease. Middle-aged women, in particular, have been reported to significantly increased disease rates after menopause; however, their adherence health behaviors lower than that of other populations. This study examined the factors associated with MetS prevention based on Information-Motivation-Behavior skills model and described relationships between components middle-aged women.This investigative used an online...

The aim of this study was to examine factors affecting depression based on an ecological system perspectives among postmenopausal middle-aged women. This the data 1,300 women aged 50-64 years from 16th Korea Welfare Panel Study. Using SPSS program, descriptive statistical analysis, independent sample t-test, correlation and multiple regression analysis were conducted. As a result, subjective health status(β= -.172, p<.001), self-esteem(β = -.395, family relation satisfaction(β= -.104,...