A5100655003- Gastrointestinal motility and disorders
- Diet and metabolism studies
- Pelvic floor disorders treatments
- Pediatric Pain Management Techniques
- Infant Health and Development
- Bariatric Surgery and Outcomes
- Embedded Systems and FPGA Design
- Congenital gastrointestinal and neural anomalies
- Pluripotent Stem Cells Research
- Infant Development and Preterm Care
- Mesenchymal stem cell research
- Atrial Fibrillation Management and Outcomes
- Birth, Development, and Health
- High Altitude and Hypoxia
- Botulinum Toxin and Related Neurological Disorders
- Animal Behavior and Welfare Studies
- 3D Printing in Biomedical Research
- Gastroesophageal reflux and treatments
- Wireless Sensor Networks and IoT
- Pancreatic function and diabetes
- Molecular Biology Techniques and Applications
- Cardiac Valve Diseases and Treatments
- Advanced Computational Techniques and Applications
- Solar-Powered Water Purification Methods
- Cardiac Structural Anomalies and Repair
California Medical Innovations Institute
2016-2023
China University of Mining and Technology
2007
The hemodynamic and geometric factors leading to propagation of acute Type B dissections are poorly understood. objective is elucidate whether parameters increase the predilection for aortic dissection propagation. A pulse duplicator set-up was used on porcine aorta with a single entry tear. Mean pressures 100 180 mmHg were used, ranging from 40 200 mmHg. varying conditions (%circumference tear: 15–65%, axial length: 0.5–3.2 cm) tested two flap thicknesses (1/3rd 2/3rd thickness vessel wall,...
Transport of colonic content is a complex physiologic process through which contents are received from the ileum, solidify during passage, and finally expelled rectum anus.1Yamada T et al. (eds). Textbook Gastroenterology, 5th Edition. Blackwell, 2009. pp. 1717–1744.Google Scholar,2Gregersen H, Christensen J. Clinical mechanics in Gut. An Introduction. Bentham Publishers, 2016.Google Scholar Colonic motility transit difficult to study where mechanical loading motion need be quantified. Since...
Fecobionics was used to assess pressures, orientation, bending, shape, and cross-sectional area (CSA) changes during defecation. This study aimed evaluate the device feasibility performance in swine.Twelve pigs had wired or wireless devices inserted rectum. The bag distended simulate feces data were acquired simultaneously whole experiment. Six euthanized immediately after procedure for evaluation of acute injury anorectum (acute group). remaining lived two weeks before euthanasia long-term...
Several technologies have been developed for assessing anorectal function including the act of defecation. We used a new prototype Fecobionics technology, multi-sensor simulated feces, to visualize defecatory patterns and introduced metrics physiology assessment in normal subjects. Fourteen subjects with fecal incontinence constipation questionnaire scores were studied. The 10-cm-long device provided measurements axial pressures, orientation, bending, shape. bag was distended...
Objective: Left atrial appendage (LAA) occlusion or exclusion has been used in patients with fibrillation to prevent stroke, but the techniques and devices have shortcomings. This study aims validate safety feasibility of a novel LAA inversion procedure. Methods: procedures were done six pigs. Before procedure at 8 weeks postoperatively, heart rate, blood pressure, electrocardiogram (ECG) recorded. The serum concentration natriuretic peptide (ANP) was measured. observed measured by...
It is the protocol of Fecobionics test in normal subjects. Briefly, device will be inserted into participants' rectum and several motions (cough, squeeze, straining) done. After motions, bag inflated, participant may have different sensations during inflation. If falls out before completion test, it re-inserted gently. Data recorded shown real time. Each tested up to 4 times at following dates: The day percutaneous nerve evaluation (PNE) (pre-PNE), one after PNE (day 1), seven days 7),...
It is the protocol of Fecobionics test in normal subjects. Briefly, device will be inserted into participants' rectum and several motions (cough, squeeze, straining, push) done. After motions, bag inflated participant may have different sensations during inflation. Data recorded shown real time.
We developed a novel wireless device (Fecobionics) for mapping colonic and anorectal neuromuscular function. Our hypothesis is that the Fecobionics will be safe to use repeated testing without caused mucosal damage or any unwanted adverse effects. Validation of this innovative approach map describe objectively (without disturbing transport defecation processes) characteristics signatures during initial entry from rectum into relaxing anal canal. Twelve Mongrel dogs assigned two groups: group...
Objective We developed a novel wireless device (Fecobionics) for mapping colonic and anorectal neuromuscular function. Fecobionics measures pressures, cross‐sectional areas bending of the transmits data to receiver unit outside body (figure 1 ). This study evaluated safety in dogs relative predicate THD SensyProbe biofeedback. Furthermore, physiological were obtained with Fecobionics. Methods Twelve male Mongrel 25kg weight assigned into two groups: group control (N=6 each). transanally...
We developed a novel wireless device (Fecobionics) for mapping colonic and anorectal neuromuscular function. The hypothesis of this protocol is that the Fecobionics can test pressures, orientation, bending, shape, cross-sectional area changes in colon rectum. To validate our hypothesis, we inserted to proximal colon, either through cannula or colonoscopy, followed by data transmission recording.
Protocols for Hematoxylin and Eosin staining Immunofluorescence two SPARC datasets: Safety Study of Wireless Fecobionics Device testing predicate device Fecobionics. The procedures were approved by Calmi2 Institutional Animal Care Use Committee (IACUC) Mongrel dogs randomly assigned into groups: the group, THD SensyProbe control group. All animals anesthetized, devices transanally inserted rectum, then inflated at 20 ml. Six minutes later removed either naturally or manually. in each group...
Objective This study aimed to determine the change of gastrointestinal (GI) emptying time after ileal interposition (IT) and elucidate role altered GI peristalsis in diabetic control. Materials Methods Twelve male Goto-Kakizaki rats were randomly divided into IT sham groups. Body weight food intake recorded. Oral glucose tolerance test (OGTT), insulin (ITT), plasma glucagon-like peptide-1 (GLP-1), gastric measured at baseline 4 8 weeks operation. At 9 postoperatively, group given atropine...