A5007711303- Optical Coherence Tomography Applications
- Photoacoustic and Ultrasonic Imaging
- Random lasers and scattering media
- Optical Imaging and Spectroscopy Techniques
- Digital Holography and Microscopy
- Thermography and Photoacoustic Techniques
- Optical and Acousto-Optic Technologies
- Advanced Optical Sensing Technologies
- Spectroscopy Techniques in Biomedical and Chemical Research
- Optical measurement and interference techniques
- Advanced Fluorescence Microscopy Techniques
- Microwave Imaging and Scattering Analysis
- Microwave and Dielectric Measurement Techniques
- Superconducting and THz Device Technology
- Nanoplatforms for cancer theranostics
- Near-Field Optical Microscopy
- Optical Systems and Laser Technology
Korea Advanced Institute of Science and Technology
2022-2025
Institute for Basic Science
2016-2024
Korea University
2015-2024
Korea Institute of Brain Science
2022
Abstract Interferometry often serves as an essential building block of wavefront shaping systems to obtain optimal solutions. In this tutorial, we provide a Monte Carlo simulation tool calculate the accuracy interferometric measurement and its impact on in context focusing through disordered media. particular, have focused evaluating fidelity under influence shot noise with practical considerations operation digital image sensors, including read-out dark current noises, digitization finite...
Abstract To extend the imaging depth of high-resolution optical microscopy, various gating operations—confocal, coherence, and polarization gating—have been devised to filter out multiply scattered wave. However, is still limited by wave that bypasses existing operations. Here, we present a space method, whose mechanism independent methods yet effective enough complement them. Specifically, reconstruct an image only using ballistic acousto-optically modulated at object plane. The suppresses...
Various external gating approaches, based on position, time, and polarization, have proven to be effective in selectively rejecting multiply scattered waves, thereby extending the imaging depth of deep-tissue optical microscopy. However, a highly scattering medium, significant portion waves can bypass these operations because dissociation between wave properties inside outside medium. Here, we propose method, termed volumetric gating, that introduces ultrasound focus confocal reflectance...
Optical imaging of objects embedded within scattering media such as biological tissues suffers from the loss resolving power. In our previous work, we proposed an approach called collective accumulation single (CASS) microscopy that attenuates this detrimental effect multiple light by combining time-gated detection and spatial input-output correlation. present perform a rigorous theoretical analysis on to optical transfer function CASS microscopy. particular, frequency-dependent signal noise...
Abstract Photoacoustic imaging offers both high optical contrast and substantial depth, serving as a robust tool for diverse biological medical applications. While piezoelectric ultrasound transducers have traditionally been employed acoustic pressure measurements array-based configurations enabled high-speed volumetric imaging. However, these approaches often require physical contact with the specimen under face limitations in spatial sampling bandwidth. To address challenges, we present an...
Photoacoustic tomography (PAT) offers high optical contrast with acoustic imaging depth, making it essential for biomedical applications. While many all-optical systems have been developed to address limitations of ultrasound transducers, such as limited spatial sampling and path obstructions, measuring surface displacements on rough dynamic tissues remains challenging. Existing methods often lack sensitivity in vivo or are complex time-consuming. Here, we present an PAT system that enables...
We present an approach that maintains full optical resolution in imaging deep within scattering media. Imaging depth of 11.5 times the mean free path was achieved with near-diffraction-limit 1.5 μm.
High-resolution optical microscopy suffers from a low contrast in scattering media where multiply scattered wave obscures ballistic used for image formation. To extend the imaging depth, various gating operations - confocal, coherence, and polarization have been devised to filter out wave. However, these methods are imperfect as they all act on detection plane located outside medium. Here, we present new scheme, called 'space' gating, that rejects directly at object inside Specifically,...
We present a spatial gating of volumetric multiple scattering noises inside medium. This technique is realized by confocal detection with acousto-optic modulation, which enhances the visibility ballistic signals and enables noninvasive bioimaging.
The imaging depth of deep-tissue optical microscopy is governed by the performance gating operation that suppresses multiply scattered waves obscuring ballistic waves. Although various operations based on confocal, time-resolved/coherence-gated, and polarization-selective detections have proven to be effective, each has its own limitation; certain types can bypass gating. Here, we propose a method, volumetric gating, introduces ultrasound focus confocal reflectance suppress traveling outside...