Jae‐Seung Lee

ORCID: 0000-0002-4077-2043
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About
Contact & Profiles
Research Areas
  • Advanced biosensing and bioanalysis techniques
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Fuel Cells and Related Materials
  • Electrocatalysts for Energy Conversion
  • Optical Network Technologies
  • Nanocluster Synthesis and Applications
  • Advanced Photonic Communication Systems
  • Semiconductor Lasers and Optical Devices
  • Biosensors and Analytical Detection
  • Photonic and Optical Devices
  • Global Energy Security and Policy
  • Nanomaterials for catalytic reactions
  • Advanced Nanomaterials in Catalysis
  • Advanced Fiber Laser Technologies
  • Copper-based nanomaterials and applications
  • Asymmetric Synthesis and Catalysis
  • GaN-based semiconductor devices and materials
  • Advancements in Solid Oxide Fuel Cells
  • Quantum Dots Synthesis And Properties
  • Advanced battery technologies research
  • Synthetic Organic Chemistry Methods
  • Semiconductor materials and devices
  • RNA Interference and Gene Delivery
  • Radio Frequency Integrated Circuit Design
  • Advanced Optical Network Technologies

Korea University
2016-2025

Inha University
2019-2024

Electronics and Telecommunications Research Institute
1994-2024

Daegu University
2024

Toyota Research Institute
2010-2023

Obihiro University of Agriculture and Veterinary Medicine
2019-2023

Toyota Motor North America (United States)
2012-2023

Soongsil University
2020-2022

SK Group (South Korea)
2020-2022

Pohang Iron and Steel (South Korea)
2010-2022

Color is everything: Hg2+ in aqueous media detected by the formation of thymidine–Hg2+–thymidine coordination complexes, which raises melting temperature DNA-hybridized gold nanoparticle probes and thus at disperse effect a purple-to-red color change. The method has very high sensitivity selectivity, it provides simple fast colorimetric readout (see picture). Mercury widespread pollutant with distinct toxicological profiles, exists variety different forms (metallic, ionic, as part organic...

10.1002/anie.200700269 article EN Angewandte Chemie International Edition 2007-04-27

We report the development of a highly sensitive and selective colorimetric detection method for cysteine based upon oligonucleotide-functionalized gold nanoparticle probes that contain strategically placed thymidine−thymidine (T−T) mismatches complexed with Hg2+. This assay relies distance-dependent optical properties nanoparticles, sharp melting transition oligonucleotide-linked aggregates, very coordination Hg2+ cysteine. The concentration can be determined by monitoring naked eye or...

10.1021/nl0727563 article EN Nano Letters 2008-01-19

We have developed the chemistry for preparing a universal probe and appropriate nano- microparticle labels that can be used to do highly selective multiplexed detection of three protein cancer markers at low-femtomolar concentration in buffer serum media. The approach relies on new version biobarcode amplification method offers opportunities studying multiple single sample. This could lead forms disease diagnosis monitoring recurrence variety settings.

10.1021/ja0613106 article EN Journal of the American Chemical Society 2006-06-09

We report the development of a previously undescribed gold nanoparticle bio-barcode assay probe for detection prostate specific antigen (PSA) at 330 fg/mL, automation assay, and results clinical pilot study designed to assess ability detect PSA in serum 18 men who have undergone radical prostatectomy cancer. Due lack sensitivity, available immunoassays are often not capable detecting after prostatectomy. This new is approximately 300 times more sensitive than commercial immunoassays....

10.1073/pnas.0904719106 article EN Proceedings of the National Academy of Sciences 2009-10-20

We report the development of a novel colorimetric nitrite and nitrate ion assay based upon gold nanoparticle probes functionalized with Griess reaction reagents. This takes advantage distance-dependent plasmonic properties nanoparticles ability to facilitate cross coupling modified aniline naphthalene moieties. The works on concept kinetic end point can be triggered at EPA limit for this in drinking water (highlighted red, microM). rapid simple could useful on-site quality monitoring.

10.1021/ja901609k article EN Journal of the American Chemical Society 2009-04-15

The safe and effective delivery of RNA therapeutics remains the major barrier to their broad clinical application. Here we develop a new nanoparticulate system based on inorganic particles biodegradable polycations. First, gold nanoparticles were modified with hydrophilic polymer poly(ethylene glycol) (PEG), then small interfering (siRNA) was conjugated via disulfide linkages, ∼30 strands siRNA per nanoparticle. coated library end-modified poly(β-amino ester)s (PBAEs), previously identified...

10.1021/nl9009793 article EN Nano Letters 2009-05-07

A synthesis strategy for the systematic control of pore wall thickness has been developed mesoporous silicas with 2-D hexagonal order using ionic and nonionic surfactant mixtures. The have used as templates hexagonally ordered carbons controlled diameters. results are useful not only tailoring properties materials but also extending our insights into mechanism.

10.1021/ja012333h article EN Journal of the American Chemical Society 2002-01-26

A method for synthesizing composite nanoparticles with a gold shell, an Fe3O4 inner and silica core has been developed. The approach utilizes positively charged amino-modified SiO2 particles as templates the assembly of negatively 15 nm superparamagnetic water-soluble nanoparticles. SiO2−Fe3O4 electrostatically attract 1−3 Au nanoparticle seeds that act in subsequent step nucleation sites formation continuous shell around upon HAuCl4 reduction. three-layer magnetic nanoparticles, when...

10.1021/ja055056d article EN Journal of the American Chemical Society 2005-10-15

Sorting the mail: A highly selective assay for detection of multiple DNA targets in solution was developed based on gold nanoparticles with oligonucleotide reporters. Four associated infectious viruses were detected simultaneously without enzymatic amplification at mid-femtomolar concentrations.

10.1002/anie.200600124 article EN Angewandte Chemie International Edition 2006-04-07

Farbe ist alles: Hg2+ lässt sich in wässrigen Medien durch die Bildung von Thymidin-Hg2+-Thymidin-Koordinationskomplexen nachweisen, Schmelztemperatur der DNA-hybridisierten Goldnanopartikelsonden erhöht und damit Temperatur, bei Sonden unter Farbänderung Violett zu Rot dispergieren. Das Verfahren sehr empfindlich selektiv ermöglicht ein einfaches schnelles kolorimetrisches Auslesen (siehe Bild).

10.1002/ange.200700269 article DE Angewandte Chemie 2007-04-27

We have developed a chip-based scanometric method for the detection of mercuric ion (Hg2+). This takes advantage cooperative binding and catalytic properties DNA-functionalized gold nanoparticles selective thymine−thymine mismatch Hg2+. The limit this assay in buffer environmentally relevant samples (lake water) is 10 nM (2 ppb) Hg2+, which U.S. Environmental Protection Agency (EPA) [Hg2+] drinkable water 1 order magnitude lower than previous colorimetric assays. capable discriminating Hg2+...

10.1021/ac801046a article EN Analytical Chemistry 2008-07-30

The ability to wirelessly power electrical devices is becoming of greater urgency as a component energy conservation and sustainability efforts. Due health safety concerns, most wireless transfer (WPT) schemes utilize very low frequency, quasi-static, magnetic fields; occurs via magneto-inductive (MI) coupling between conducting loops serving transmitter receiver. At the "long range" regime - referring distances larger than diameter largest loop WPT efficiency in free space falls off...

10.1038/srep03642 article EN cc-by-nc-nd Scientific Reports 2014-01-10

Experimental results are presented for heat flux cloaking, focusing, and reversal in ultra-thin anisotropic composites. A two-material system is utilized the device design, which features an annular region flow control. The effective thermal conductivity layout of composite specified through logical combination base material constituents. Heat transfer considering conduction-convection numerically predicted experimentally verified via infrared thermography. Biot number analysis reveals...

10.1063/1.4816775 article EN Applied Physics Letters 2013-08-05

We describe the facile synthesis of stable gold nanoparticle clusters densely functionalized with DNA (DNA−AuNP clusters) using dithiothreitol and monothiol their thermally reversible assembly properties. The size exhibits a very narrow distribution can be easily controlled by adjusting stoichiometry DNA, leading to variety colors due surface plasmon resonance AuNP clusters. Importantly, DNA−AuNP exhibit highly cooperative melting properties distinctive diverse color changes depending on...

10.1021/nl9030709 article EN Nano Letters 2009-11-20

10.1007/s12205-016-0194-1 article EN cc-by-nc-nd KSCE Journal of Civil Engineering 2016-12-02

This article introduces a 192-Gb 896-GB/s 12-high stacked third-generation high-bandwidth memory (HBM3 DRAM) with low power consumption and high-reliability traits. New design schemes features, including internal low-voltage signaling, center strobe calibration, through-silicon via (TSV) auto-calibration, symbol-correcting in-DRAM ECC, machine-learning-based layout optimization, allow large amounts of data transfers among the vertically base core dies limited delay mismatch or SI...

10.1109/jssc.2022.3193354 article EN IEEE Journal of Solid-State Circuits 2022-08-17

A novel and efficient approach for the numerical solution of time-dependent coupled-wave equations, which are frequently used modeling distributed-feedback, distributed Bragg reflector, Fabry-Perot laser diodes, is proposed. In this approach, equations split into two sets equations. One contains only phase factors time derivatives, other coupling terms. The separate solved exactly in their form successively. This new scheme, we call split-step time-domain model, found to require an order...

10.1109/3.848349 article EN IEEE Journal of Quantum Electronics 2000-07-01

We present a novel method for size-selectively separating mixtures of nanoparticles in aqueous media utilizing the inherent chemical recognition properties DNA and cooperative binding DNA-functionalized gold nanoparticles. have determined that melting temperatures (T(m)s) aggregates formed from interconnected by duplex are dependent upon particle size. This effect is proposed to derive larger contact areas between particles therefore increased cooperativity, leading higher T(m)s. The...

10.1021/ja061651j article EN Journal of the American Chemical Society 2006-06-16
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