- Systemic Lupus Erythematosus Research
- Inflammatory Myopathies and Dermatomyositis
- Innovations in Medical Education
- Rheumatoid Arthritis Research and Therapies
- Urticaria and Related Conditions
- Vasculitis and related conditions
- Neuroendocrine Tumor Research Advances
- Multiple Myeloma Research and Treatments
- T-cell and B-cell Immunology
- Orthopedic Infections and Treatments
- Plant Pathogens and Fungal Diseases
- Dermatological and Skeletal Disorders
- Musculoskeletal Disorders and Rehabilitation
- Renal Diseases and Glomerulopathies
- Clinical Reasoning and Diagnostic Skills
- Cardiomyopathy and Myosin Studies
- Radiology practices and education
- Sarcoidosis and Beryllium Toxicity Research
- Liver Disease Diagnosis and Treatment
- Hospital Admissions and Outcomes
- Ocular Oncology and Treatments
- Peripheral Neuropathies and Disorders
- Immune Cell Function and Interaction
- Pneumothorax, Barotrauma, Emphysema
- Amyloidosis: Diagnosis, Treatment, Outcomes
University of Iowa
2002-2018
Universität Greifswald
2007-2016
University of Iowa Hospitals and Clinics
2016
Universitätsmedizin Greifswald
2012
Carver Bible College
2008
Walter Reed Army Institute of Research
1993-1996
Fitzsimons Army Medical Center
1990-1995
ABSTRACT The effect of low dose methotrexate (MTX) on postoperative complications in rheumatoid arthritis patients undergoing elective total joint arthroplasty was observed prospectively 32 patients. Patients were assigned to discontinue MTX the week prior and during surgery (Group 1, n=19) or continue throughout perioperative period 2, n=13). Nineteen Group 1 had 26 procedures, with no infections. Thirteen 2 16 4 infections: infected prostheses, fusion, deep wound infection (P=.03). No...
Abstract Objective . To test the usefulness and cost savings resulting from application of new American College Rheumatology (ACR) guidelines for assessing risk development clinically significant liver disease in rheumatoid arthritis (RA) patients treated with methotrexate (MTX). Methods One‐hundred twelve MTX‐treated RA were prospectively followed up MTX hepatotoxicity underwent biopsies according to modified Psoriatic Task Force (PTF). All graded Roenigk classification. The ACR...
Patients with systemic lupus erythematosus (SLE) who exhibit defective in vitro responses to recall antigens and normal alloantigens have been shown an abnormality antigen-presenting cell (APC) function. This study was undertaken further characterize this defect APC function patients.Mononuclear cells (MNC) from the peripheral blood of patients SLE individuals were cultured presence either antigen tetanus toxoid (TT), anti-CD3 (OKT3) monoclonal antibody, or alloantigens, proliferative...
We examined features of clinically amyopathic JDM (CAJDM), in which patients have characteristic rashes with little to no evidence muscle involvement, determine whether this is a distinct phenotype from JDM. Demographic, clinical, laboratory and treatment data 12 (9 hypomyopathic, 3 amyopathic) meeting modified Sontheimer criteria for CAJDM 60 matched Bohan Peter were examined. Differences evaluated by Fisher's exact Mann–Whitney tests, random forests logistic regression analysis. Nine (75%)...
Abstract Introduction The increased demand for clinician-educators in academic medicine necessitates additional training educational skills to prepare potential candidates these positions. Although many teaching programs residents exist, there is a lack of reports the literature evaluating similar during fellowship training. Aim To describe implementation and evaluation unique program aimed at enhancing knowledge subspecialty fellows chief residents. Setting Fellows as Clinician-Educators...
A 62-year-old male with a history of Wegener's granulomatosis and immunosuppressive therapy presented chronic olecranon bursitis. black velvety mould brown septate hyphae tapered annellides was isolated from left elbow bursa aspirate identified as an Exophiala species. Internal transcribed sequence rRNA sequencing showed the isolate to be identical oligosperma. The patient successfully treated aspiration intrabursal amphotericin B.
The practice of Evidence-based Medicine requires that clinicians assess the validity published research and then apply results to patient care. We wanted whether our soon-to-graduate medical students could appraise about a diagnostic test within clinical context compare with peers trained at other institutions.4th year who previously had demonstrated competency probability revision just starting first-year Internal residents were used for this research. Following an encounter simulated...
Hydralazine is a medication that has been used to manage hypertension and heart failure. In this case series, we report 4 patients who presented large, Midwestern academic medical center on chronic hydralazine therapy with acute kidney injury, nephritic urine sediment microscopy, the simultaneous presence of autoantibodies suggesting both drug-induced lupus vasculitis. All them had evidence pauci-immune glomerulonephritis biopsy. reported in our series are white women older than 60 years...
No AccessJournal of UrologyCLINICAL UROLOGY: Case Reports1 Feb 2004Isolated Testicular Vasculitis Presenting as a Tumor-Like Lesion FADI N. JOUDI, J. CHRISTOPHER AUSTIN, SCOTT A. VOGELGESANG, and CHRIS S. JENSEN JOUDIFADI JOUDI More articles by this author , AUSTINJ. AUSTIN VOGELGESANGSCOTT VOGELGESANG Financial interest and/or other relationship with Pfizer, Searle Merck. JENSENCHRIS View All Author Informationhttps://doi.org/10.1097/01.ju.0000103275.97385.ceAboutFull TextPDF ToolsAdd to...
Abstract Background: This prospective randomized controlled study examined outpatient clinical teaching in the presence of patient. Methods: In 2006, patients ambulatory internal medicine clinics at University Iowa were to have faculty-learner presentations either their or conference room. Staffing encounters timed and faculty, learners completed postencounter surveys. Results: Participation included 254 12 faculty. Comparison patient exam room ( n = 120) 134) staffing demonstrated increased...
Abstract Objectives Four-and-a-half LIM domains 1 (FHL1) is a muscle-specific protein. Autoantibodies against FHL1 were recently discovered in adults with idiopathic inflammatory myopathies (IIMs) and found to be associated clinical features outcomes indicative of increased disease severity. Anti-FHL1 autoantibodies have not been described children. Here, the prevalence anti-FHL1 examined large North American cohort juvenile patients IIM. Methods Sera from 338 IIM 91 healthy controls...
Sir: Alternaria, a saprophytic fungus, is seldom involved in human infection. We report case of peritonitis patient on continuous ambulatory peritoneal dialysis (CAPD) who received prophylactic, systemic antibiotics. A 55-year-old white male with end-stage renal dis ease secondary to diabetes mellitus had been CAPD 6 months prior admission. He difficulty compliancy and developed S. epidermidis 1 month was treated intraperitoneal vancomycin oral rifampin the infection resolved. His last dose...
PreviewAmyloidosis can present in myriad ways and is often confused with other diseases. To help physicians avoid diagnostic pitfalls, Drs Vogelgesang Klipple describe the various clinical amyloid syndromes, tell what differentiates them, summarize effects of infiltration on organ systems. They also assess effectiveness techniques note relative ineffectiveness medications that have been used to treat amyloidosis.
<h3>Background</h3> Sarcoidosis, a systemic disease characterized by non-caseating granulomas within affected organs, typically targets the lungs. However, approximately 10–25% of cases manifest musculoskeletal (MSK) involvement joints, muscles and bone tissue. Literature on efficacy safety TNF-alpha inhibitors (TNFi) for treatment MSK sarcoidosis is limited. <h3>Objectives</h3> Thus, we examined our experience with TNFi. <h3>Methods</h3> We conducted an IRB-approved, retrospective EMR...