A5113942002- Genital Health and Disease
- Urologic and reproductive health conditions
- Cervical Cancer and HPV Research
- Sexual function and dysfunction studies
- Ethics and Legal Issues in Pediatric Healthcare
- Male Reproductive Health Studies
- Urological Disorders and Treatments
- Female Genital Mutilation/Cutting Issues
- Herpesvirus Infections and Treatments
- Prostate Cancer Treatment and Research
- Molecular Biology Techniques and Applications
- Prostate Cancer Diagnosis and Treatment
- MicroRNA in disease regulation
- Bladder and Urothelial Cancer Treatments
- Testicular diseases and treatments
- Vascular Tumors and Angiosarcomas
- Advanced Breast Cancer Therapies
- Cancer-related molecular mechanisms research
Universidade Federal do Maranhão
2018-2024
Hospital Universitário da Universidade Federal do Maranhão
2020-2024
Universidade Católica Dom Bosco
2021
Abstract To determine the epidemiological, histopathological, and clinical characteristics of patients diagnosed with penile cancer in Brazilian state Maranhão, region highest incidence worldwide. One hundred sixteen were interviewed from July 2016 to October 2018. The majority lived a rural area (57%), worked farming (58%), had low level schooling or no (90%), married stable relationship (74%). mean age was 60.4 ± 16.51 years (range, 23–93 years). Phimosis (66%), poor/moderate genital...
Background Infection with human papillomavirus (HPV) is reported to be present in 30–50% of penile cancer cases. The immunohistochemical test for p16INK4a used as an indicator the presence HPV and a prognostic marker squamous cell carcinomas various sites. However, role this carcinoma has not yet been completely elucidated. aim study was analyze whether expression associated HPV, histological parameters, survival cancer. Methods A conducted from 2014 2016 that included 55 patients carcinoma....
Inguinal lymph node dissection plays an important role in the management of melanoma, penile and vulval cancer. is associated with various intraoperative postoperative complications significant heterogeneity classification reporting. This lack standardization challenges efforts to study report inguinal outcomes. The aim this was devise a system standardize reporting perioperative by creating worldwide collaborative, adverse events lymphadenectomy area (CALI) group.
Background: Inguinal lymph node involvement is the main prognostic factor in patients with penile cancer. However, there a lack of marker/s for metastasis. microRNAs have been investigated as potential markers prognosis various types Taking this into consideration, our goal was to determine association miR-223-3p, miR-107, and miR-21-5p expression clinicopathological characteristics, well presence metastasis Methods: Formalin-fixed paraffin-embedded squamous cell carcinoma specimens from 50...
Abstract Background Although penile cancer (PC) is uncommon in developed countries, it widespread developing countries. The state of Maranhão (Northeast, Brazil) has the highest global incidence recorded for PC, and, despite its socioeconomic vulnerability, been attributed to human papillomavirus (HPV) infection. This study aimed determine histopathological features, prevalence HPV infection, and immunohistochemical profile PC Maranhão. Methods A retrospective cohort 200 cases were...
Human papillomavirus (HPV) infection is a risk factor for penile cancer (PC). The miR-145 expression has been correlated to this virus genomic amplification. In context, work aims determine the level of in tumors infected by high-risk HPV and correlate it with clinicopathological characteristics tumor protein p53.Formalin-fixed paraffin-embedded from 52 patients PC, at diagnosis prior any treatment, were obtained. identification was performed nested type PCR, obtained qRT-PCR....
Maranhão State-Northeast Brazil-has the world's highest incidence of penile cancer. This study describes epidemiological, histopathological and clinical profile patients stricken across that Brazilian state. The is aimed at providing new data on neoplasia.402 men with cancer were studied from January 2004 to December 2018. A retrospective stage was developed collection physical electronic records. prospective performed epidemiological information through a questionnaire. surgical material...
Abstract: Pseudoangiosarcomatous squamous cell carcinoma, also called pseudovascular, pseudoangiomatoid or adenoid pseudovascular is an uncommon and highly aggressive variant of carcinoma. Histologically, it characterized by proliferation atypical keratinocytes with acantholysis formation spaces, forming anastomosed channels lined neoplastic cells that invade the dermis. These are positive for cytokeratin negative vascular markers such as CD31 CD34. There few reports this in literature....
Abstract Background: Pseudoangiosarcomatous squamous cell carcinoma, also called pseudovascular, pseudoangiomatoid or adenoid pseudovascular is an uncommon and highly aggressive variant of carcinoma. Histologically, it characterized by proliferation atypical keratinocytes with acantholysis formation spaces, forming anastomosed channels lined neoplastic cells that invade the dermis. These are positive for cytokeratin vimentin negative vascular markers such as CD31 CD34. There few reports this...