Khan Akhtar Ali

ORCID: 0000-0003-0463-197X
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About
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Research Areas
  • Bone fractures and treatments
  • Orthopedic Infections and Treatments
  • Anesthesia and Pain Management
  • Orthopedic Surgery and Rehabilitation
  • Osteoarthritis Treatment and Mechanisms
  • Hip and Femur Fractures
  • Total Knee Arthroplasty Outcomes
  • Palliative Care and End-of-Life Issues
  • Moyamoya disease diagnosis and treatment
  • Emergency and Acute Care Studies
  • Infectious Diseases and Tuberculosis
  • Spine and Intervertebral Disc Pathology
  • Musculoskeletal Disorders and Rehabilitation
  • Toxoplasma gondii Research Studies
  • Cardiac Ischemia and Reperfusion
  • Cytokine Signaling Pathways and Interactions
  • Traumatic Ocular and Foreign Body Injuries
  • Pelvic and Acetabular Injuries
  • Histiocytic Disorders and Treatments
  • Neurological Complications and Syndromes
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Hemophilia Treatment and Research
  • Blood Coagulation and Thrombosis Mechanisms
  • Ethics and Legal Issues in Pediatric Healthcare
  • Mycobacterium research and diagnosis

Huazhong University of Science and Technology
2023-2025

Tongji Hospital
2023-2025

Affiliated Hospital of Nantong University
2019

Nantong University
2019

Mansoura University
2016

University Hospital of Wales
2012

Hemophilia Center of Iran
2004

This study aimed to enhance the rehabilitation process for patients with unstable pelvic Tile C fractures resulting from polytrauma by integrating mechanotherapy using Hocoma Lokomat robotic device conventional methods. The goal was improve functional recovery outcomes and minimize pain levels following surgical intervention. A total of 74 participants, aged 21 65 years, severe were enrolled at Tongji Hospital's Department Rehabilitation 2022 2024. They randomly divided into two groups:...

10.1186/s13018-025-05833-w article EN cc-by-nc-nd Journal of Orthopaedic Surgery and Research 2025-05-02

<title>Abstract</title> <bold>Background and Objectives:</bold> With the increasing incidence of hip pelvic fractures among aging population, traditional rehabilitation methods may lack accessibility, necessitating exploration tele-rehabilitation as an effective alternative. This study aimed to evaluate feasibility effectiveness (TR) in older patients with or during home rehabilitation. <bold>Methods:</bold>A prospective observational was conducted on 70 admitted a service for femoral...

10.21203/rs.3.rs-5948279/v1 preprint EN cc-by Research Square (Research Square) 2025-02-05

Osteoarthritis (OA) is a chronic and degenerative disease marked by inflammation extracellular matrix (ECM) degeneration, contributing to synovial cartilage destruction. Accumulating evidence has demonstrated that Liver receptor homolog-1 (LRH-1), an orphan nuclear receptor, mediates inflammatory response. However, there lack of regarding the regulatory role LRH-1 in OA pathogenesis. In this study, we confirmed chondrocytes expressed LRH-1, observed its upregulation both IL-1β-treated...

10.1016/j.bcp.2025.116922 article EN cc-by-nc-nd Biochemical Pharmacology 2025-04-01

Abstract Background and objectives It is known that difficulty sleeping after a fracture can have negative effects on both mental physical health may prolong the recovery process. The objective of this study to explore how sleep quality psychological are linked in patients with pelvic acetabulum fractures. Methods A was conducted 265 between 2018 2022 who had suffered examined various factors, including age, gender, cause injury, post-operative complications, injury severity. employed...

10.1186/s12877-024-04929-y article EN cc-by BMC Geriatrics 2024-04-04

Summary. High‐dose factor prophylaxis, defined as the infusion of 25–40 (F) VIII International Units (IU) kg bodyweight (bw) −1 ≥ × 3 per week, started at age 1–2 years life in boys with severe haemophilia A prevents development significant bleed‐related arthropathy. However, programmes prophylaxis are very expensive and venous access is a challenge. To ascertain patterns Canada during period global shortage recombinant FVIII concentrate survey was conducted 2001. The response rate 83%...

10.1111/j.1365-2516.2004.01045.x article EN Haemophilia 2004-11-01

Background and purpose: This prospective observational study aimed to investigate the occurrence of avascular necrosis (AVN) femoral head in COVID-19 patients through MRI scans. The examined patterns AVN 110 individuals who had undergone conventional therapy reported hip discomfort. highlights importance considering as a potential complication therapy, particularly younger experience Methods: Individuals corticosteroid treatment for experienced discomfort during 6 months between January 2022...

10.1177/11207000241233906 article EN Hip International 2024-03-08

Surgery is currently the only effective treatment for retroperitoneal tumors that do not involve any specific organ. The use of robots removing both benign and malignant considered safe feasible. However, there insufficient evidence to determine whether robotic tumor resection (RMBRs) superior open (OMBRs). This study compares short-term outcomes excision with same-sized tumors.

10.1007/s00464-024-10848-1 article EN cc-by Surgical Endoscopy 2024-04-24

Abstract Background and objectives Local anesthetics (LAs) are widely used to infiltrate into surgical wounds for postoperative analgesia. Different adjuvants like dexamethasone dexmedetomidine, when added LA agents, could improve prolong The aim of this trial was evaluate the analgesic efficacy opioid-sparing properties dexmedetomidine ropivacaine wound infiltration in transforaminal lumbar interbody fusion (TLIF). Methods We conducted a controlled study among 68 adult patients undergoing...

10.1186/s13018-023-04145-1 article EN cc-by Journal of Orthopaedic Surgery and Research 2023-09-04

The posterolateral tibial plateau fracture is an uncommon intra-articular injury and mostly needed surgery. However, its surgical approach remains controversial. This manuscript describes anterolateral to treat fractures evaluates the patient's functional outcomes. From June 2018 July 2021 seventeen patients with were surgically treated through approach. intraoperative postoperative follow-up indicators recorded. reduction quality of was assessed using Rasmussen radiological score,...

10.52628/89.2.11211 article EN Acta Orthopaedica Belgica 2023-06-01

<title>Abstract</title> This case report describes the medical journey of a 9-year-old girl who was diagnosed with Rosai-Dorfman disease (RDD), rare disorder characterized by overproduction histiocytes within lymph nodes. The patient RDD after experiencing left calf pain and discomfort. Initial imaging revealed abnormal signals localized low-density foci in tibia, subsequent MRI scans indicated possible tumor. diagnosis confirmed through puncture biopsy, which granulomatous tissue consistent...

10.21203/rs.3.rs-5361982/v1 preprint EN cc-by Research Square (Research Square) 2024-11-27

Abstract Background Hospice care is the primary field of public health that establishes minimum standards for patients who are nearing end their lives. All individuals, irrespective race, social status, or cultural heritage, should be able to obtain this healthcare. Scientific literature has brought attention inequalities in healthcare based on race and ethnicity. The focus article examine previous research impact hospice infected children, parents, siblings. Providing can help children...

10.21203/rs.3.rs-3593556/v1 preprint EN cc-by Research Square (Research Square) 2023-11-14

We describe two patients with reversible cerebral vasoconstriction syndrome (RCVS). <h3>Patient 1</h3> A 53-year-old woman presented unprovoked recurrent thunderclap headache over 2 days together nausea, neck stiffness and photophobia. Examination was normal except for mild stiffness. CT brain scan showed grade 1 subarachnoid haemorrhage (SAH). Cerebral catheter angiography demonstrated severe restriction in the anterior circulation a string of beads appearance no vascular malformation or...

10.1136/jnnp-2012-304200a.1 article EN Journal of Neurology Neurosurgery & Psychiatry 2012-11-01
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