- Respiratory Support and Mechanisms
- Cardiac Arrest and Resuscitation
- Trauma and Emergency Care Studies
- Coronary Artery Anomalies
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Vascular Malformations and Hemangiomas
- Vascular anomalies and interventions
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Mechanical Circulatory Support Devices
- Myasthenia Gravis and Thymoma
- Hemostasis and retained surgical items
- Neonatal Respiratory Health Research
- Cardiovascular Issues in Pregnancy
- Tracheal and airway disorders
- Spinal Fractures and Fixation Techniques
- Renal function and acid-base balance
- Healthcare Systems and Challenges
- RNA Interference and Gene Delivery
- Hemodynamic Monitoring and Therapy
- Neuroscience of respiration and sleep
- Sepsis Diagnosis and Treatment
- RNA modifications and cancer
- Surgical Sutures and Adhesives
- Inhalation and Respiratory Drug Delivery
- Airway Management and Intubation Techniques
SUNY Upstate Medical University
2019-2024
Upstate University Hospital
2021-2022
In a large animal model of ARDS, recruitment/derecruitment caused greater VILI than overdistension, whereas both mechanisms together severe lung damage. These findings suggest that eliminating cyclic recruitment and derecruitment during mechanical ventilation should be preeminent management goal for the patient with ARDS. The airway pressure release (APRV) mode can achieve this if delivered an expiratory duration (T Low ) is brief enough to prevent at end expiration.
<h3>BACKGROUND:</h3> Lung volume measurements are important for monitoring functional aeration and recruitment, may help guide adjustments in ventilator settings. The expiratory phase of APRV provide physiologic information about lung based on the flow-time slope, angle, time to approach a no-flow state (T<sub>Exp</sub>). We hypothesized that flow rate would correlate with estimated (ELV), as measured using modified nitrogen washout/washin technique large animal injury model....
Introduction: The factors influencing meconium aspiration syndrome (MAS) severity remain poorly understood. In a piglet model of MAS, we hypothesized the respiratory microbiome would reflect bacterial signature with short-chain fatty acid (SCFA) accumulation as byproduct fermentation. Methods: Cesarean section at approximately 115-day term was performed on two sows. Male (9) and female (3) piglets were delivered, instrumented, anesthetized, randomized into Control (n = 6) or MAS group 6)....
Abstract Background An anomalous origin and inter-arterial course of the right coronary artery is a rare anomaly that can lead to sudden ischemic cardiac death if left untreated. We present case patient with an originating from sinus was managed bypass surgery using suitable internal mammary conduit. The proximal ligated prevent competitive flow. Case Presentation A 69 year-old-male ten-year history intermittent chest pain dyspnea negative workup underwent catheterization, which showed (RCA)...
Although there are many hemostatic agents available for use on the battlefield, uncontrolled hemorrhage is still primary cause of preventable death. Current dressings include QuikClot® Combat Gauze (QCCG) and XStat®, which have inadequate success in reducing mortality. To address this need, a new material was developed using shape memory polymer (SMP) foams, demonstrate biocompatibility, rapid clotting, recovery to fill wound site. SMP foam efficacy examined lethal, noncompressible porcine...
Abstract Background Mediastinal teratomas are rare tumors that most frequently occur in the anterior mediastinum. The majority of these benign and slow growing. Due to their low malignant potential, treatment for is surgical resection. management has shifted from invasive approaches such as a sternotomy minimally ones robotic-assisted thoracoscopic resections. Though many cases mediastinal have been reported, we present case locally advanced teratoma requiring patient repositioning change...
Abstract Background: An anomalous origin and inter-arterial course of the right coronary artery is a rare anomaly that can lead to sudden ischemic cardiac death if left untreated. We present case patient with an originating from cusp was managed bypass surgery using internal mammary conduit. The proximal ligated prevent competitive flow. Case Presentation: A 69 year-old-male ten-year history intermittent chest pain dyspnea negative workup underwent catheterization, which showed (RCA) cusp,...
During mechanical ventilation, cyclic recruitment and derecruitment (R/D) of alveoli result in focal points heterogeneous stress throughout the lung. In acutely injured lung, rates at which can be recruited or derecruited may also altered, requiring longer times higher pressure levels to during inspiration, but shorter lower minimize collapse exhalation. this study, we used a computational model simulate effects airway release ventilation (APRV) on acinar recruitment, with varying...
Ramcharran, Harry; Satalin, Joshua; Blair, Sarah; Andrews, Penny; Habashi, Nader; Gaver, Donald; Gatto, Louis; Bates, Jason; Nieman, Gary; Kollisch-Singule, Michaela Author Information
Blair, Sarah; Ramcharran, Harry; Satalin, Joshua; Andrews, Penny; Habashi, Nader; Gaver, Donald; Gatto, Louis; Bates, Jason; Nieman, Gary; Kollisch-Singule, Michaela Author Information