A5032223828- RNA and protein synthesis mechanisms
- Bacteriophages and microbial interactions
- Genomics and Phylogenetic Studies
Microbiology Institute of Shaanxi
2022
Institute of Microbiology
2022
Chinese Academy of Sciences
2022
University of Chinese Academy of Sciences
2022
Impact statement Spindle‐shaped viruses exclusively infect archaea. Fuselloviruses represent a large group of spindle‐shaped and hyperthermophilic archaea the order Sulfolobales . Although first fusellovirus was identified nearly 40 years ago, mechanism host infection by these remains poorly understood. Here, we show that SSV19, isolated from hot spring in Philippines, is capable hydrolyzing cell surface glycan as heptasaccharide chain QuiS 1 Hex 4 HexNAc 2 Our findings provide significant...
Archaeal viruses with a spindle-shaped virion are abundant and widespread in extremely diverse environments. However, efforts to obtain the high-resolution structure of virus have been unsuccessful. Here, we present SSV19, infecting hyperthermophilic archaeon Sulfolobus sp. E11-6. Our near-atomic reveals an unusual sevenfold symmetrical tail consisting tailspike, nozzle, adaptor proteins. The capsid shell is formed by seven left-handed helical strands, constructed hydrophobic major protein,...