Kai Zhao

ORCID: 0000-0003-0468-2128
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About
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Research Areas
  • Plant Molecular Biology Research
  • Plant Gene Expression Analysis
  • Genomics and Phylogenetic Studies
  • Plant Stress Responses and Tolerance
  • Photosynthetic Processes and Mechanisms
  • Plant biochemistry and biosynthesis
  • Plant Pathogens and Fungal Diseases
  • Plant Reproductive Biology
  • Peanut Plant Research Studies
  • Biofuel production and bioconversion
  • Plant and animal studies
  • SARS-CoV-2 and COVID-19 Research
  • Bioenergy crop production and management
  • Agricultural pest management studies
  • Plant Physiology and Cultivation Studies
  • Horticultural and Viticultural Research
  • Plant and Fungal Species Descriptions
  • Genetic diversity and population structure
  • Viral gastroenteritis research and epidemiology
  • Fish Ecology and Management Studies
  • Cancer-related molecular mechanisms research
  • Identification and Quantification in Food
  • Chromosomal and Genetic Variations
  • GABA and Rice Research
  • Plant tissue culture and regeneration

Henan Agricultural University
2019-2025

Fujian Normal University
2019-2025

Jiamusi University
2025

University of Regina
2020-2024

Nanjing Agricultural University
2016-2024

Fourth People's Hospital of Sichuan Province
2023-2024

The Fourth People's Hospital
2023-2024

University of Chinese Academy of Sciences
2021-2024

Northeast Forestry University
2017-2024

Chinese Academy of Sciences
2015-2024

Abstract Since the outbreak of severe acute respiratory syndrome (SARS) 18 years ago, a large number SARS-related coronaviruses (SARSr-CoVs) have been discovered in their natural reservoir host, bats 1–4 . Previous studies shown that some bat SARSr-CoVs potential to infect humans 5–7 Here we report identification and characterization new coronavirus (2019-nCoV), which caused an epidemic Wuhan, China. The epidemic, started on 12 December 2019, had 2,794 laboratory-confirmed infections...

10.1038/s41586-020-2012-7 article EN cc-by Nature 2020-02-03

Since the SARS outbreak 18 years ago, a large number of severe acute respiratory syndrome related coronaviruses (SARSr-CoV) have been discovered in their natural reservoir host, bats. Previous studies indicated that some those bat SARSr-CoVs potential to infect humans. Here we report identification and characterization novel coronavirus (nCoV-2019) which caused an epidemic humans, Wuhan, China. The epidemic, started from December 12th, 2019, has 198 laboratory confirmed infections with three...

10.1101/2020.01.22.914952 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2020-01-23

The MYB transcription factors and plant hormone ABA have been suggested to play a role in fruit anthocyanin biosynthesis, but supporting genetic evidence has lacking sweet cherry. present study describes the first functional characterization of an R2R3-MYB factor, PacMYBA, from red-colored cherry cv. Hong Deng (Prunus avium L.). Transient promoter assays demonstrated that PacMYBA physically interacted with several anthocyanin-related basic helix–loop–helix (bHLH) activate promoters PacDFR,...

10.1093/pcp/pcu013 article EN Plant and Cell Physiology 2014-01-19

Abstract Bud dormancy transition is a vital developmental process for perennial plant survival. The precisely regulated by diverse endogenous genetic factors and environmental cues, but the mechanisms are not yet fully understood. Prunus mume an ideal crop bud analysis because of its early spring-flowering characteristics small sequenced genome. Here, we analyzed transcriptome profiles at three endodormancy stages natural flush stage using RNA sequencing combined with phytohormone sugar...

10.1038/s41598-018-23108-9 article EN cc-by Scientific Reports 2018-03-23

Abstract Tibetan loaches are the largest group of fishes and well adapted to Plateau. To investigate origin their adaptations Plateau, we determined 32 complete mitochondrial genomes that included 29 loach species, two Barbatula species Schistura longus . By combining these newly sequences with other previously published genomes, assembled a large mitogenomic data set (11,433 bp) 96 in superfamily Cobitoidea, phylogenetic status genus Triplophysa The resulting phylogeny strongly supported...

10.1038/srep29690 article EN cc-by Scientific Reports 2016-07-15

Abstract Background The bZIP gene family, which is widely present in plants, participates varied biological processes including growth and development stress responses. How do the genes regulate such processes? Systems biology powerful for mechanistic understanding of functions. However, studies have not yet been reported poplar. Results In this study, we identified 86 poplar transcription factors described their conserved domains. According to results phylogenetic tree, divided these...

10.1186/s12870-021-02879-w article EN cc-by BMC Plant Biology 2021-03-01

Chronic hyperglycemia, a hallmark of diabetes, can trigger inflammatory responses in the kidney, leading to diabetic nephropathy (DN). Follistatin-like protein 1 (FSTL1) has emerged as potential therapeutic target various kidney diseases. This study investigated effect high glucose on FSTL1 expression and its role oxidative stress cellular transdifferentiation injury HK-2 human proximal tubule epithelial cells, model DN. We FSTL1's level cells exposed using Western blotting quantitative...

10.1038/s41598-024-84462-5 article EN cc-by-nc-nd Scientific Reports 2025-01-02

Abstract Background Auxin plays important roles in hormone crosstalk and the plant’s stress response. The auxin-responsive Gretchen Hagen3 ( GH3 ) gene family maintains hormonal homeostasis by conjugating excess indole-3-acetic acid (IAA), salicylic (SA), jasmonic acids (JAs) to amino during hormone- stress-related signaling pathways. With sequencing of apple Malus × domestica genome completed, it is possible carry out genomic studies on genes indentify candidates with abiotic/biotic...

10.1186/1471-2164-14-297 article EN cc-by BMC Genomics 2013-05-02

Endogenous retroviruses (ERVs) comprise 8% of the human genome and are common in all vertebrate genomes. The only retrovirus known to be currently transitioning from exogenous endogenous form is koala (KoRV), making koalas (Phascolarctos cinereus) ideal for examining early stages retroviral endogenization. To distinguish KoRV proviruses, we isolated genomic regions flanking integration sites. In three wild southern Australian koalas, there were fewer loci than captive Queensland consistent...

10.1093/molbev/msu275 article EN Molecular Biology and Evolution 2014-09-25

A total of 181 wheat flour and 142 wheat-based foods including dried noodle, steamed bread collected in China were analyzed for alternariol (AOH), monomethyl ether (AME), tentoxin (TEN) tenuazonic acid (TeA) by ultra-performance liquid chromatography-electrospray ionization-tandem mass spectrometry. TeA was the predominant toxin found 99.4% samples at levels ranging from 1.76 μg/kg to 520 μg/kg. TEN another Alternaria frequently detected (97.2%) between 2.72 129 AOH AME 11 (6.1%) 16.0 98.7...

10.1371/journal.pone.0132019 article EN cc-by PLoS ONE 2015-06-29

The MYB, one of the largest transcription factor families in plants, is related to various biological processes. For an example, R2R3-MYB family plays important role regulation primary and secondary metabolism, plant growth development, responses hormones stresses. However, functional studies on poplar genes are limited. In this study, we identified 207 that unevenly distributed 19 chromosomes poplar, followed by characterization their conserved domains. On basis phylogenetic analysis, these...

10.3389/fpls.2020.571881 article EN cc-by Frontiers in Plant Science 2020-10-16

Xyloglucan endotransglucosylase/hydrolase (XTH) family plays an important role in cell wall reconstruction and stress resistance plants. However, the detailed characteristics of XTH genes their expression pattern under salt have not been reported poplar.

10.1186/s12864-021-08134-8 article EN cc-by BMC Genomics 2021-11-08

Drought is one of the main environmental factors limiting plant growth and development. The AP2/ERF transcription factor (TF) ERF194 play key roles in poplar drought-stress tolerance. However, physiological mechanism remains to be explored. In this study, ERF194-overexpression (OX), suppressed-expression (RNA interference, RNAi), non-transgenic (WT) clone 717 were used study physiology role drought Morphological methods systematically analyze status, antioxidant enzyme activity,...

10.3390/ijms24010788 article EN International Journal of Molecular Sciences 2023-01-02

Heat shock factors (HSFs) are the key regulators of heat stress responses and play pivotal roles in tissue development temperature-induced regulation secondary metabolites. In order to elucidate HSFs Cymbidium ensifolium, we conducted a genome-wide identification CeHSF genes predicted their functions based on structural features splicing patterns. Our results revealed 22 HSF family members, with each gene containing more than one intron. According phylogenetic analysis, 59.1% were grouped...

10.3390/ijms25021002 article EN International Journal of Molecular Sciences 2024-01-13

Rose is an important ornamental crop cultivated globally for perfume production. However, our understanding of the mechanisms underlying scent production and molecular breeding fragrance hindered by lack a reference genome tea roses. We present first complete telomere-to-telomere (T2T) Rosa gigantea, with high quality (QV > 60), including detailed characterization structural features repetitive regions. The expansion genes associated phenylpropanoid biosynthesis may account unique scent....

10.1038/s41467-024-52782-9 article EN cc-by-nc-nd Nature Communications 2024-09-30

DREB2 (dehydration-responsive element-binding factor 2)-type transcription factors play a critical role in the stress-related regulation network plants. In this study, we isolated and characterized homolog from Malus sieversii Roem., designated MsDREB2C (GenBank accession No. JQ790526). localized to nucleus transactivated reporter genes yeast strain YGR-2. Quantitative real-time PCR analysis demonstrated that was constitutively expressed significantly induced by drought, salt, cold, heat...

10.1093/pcp/pct087 article EN Plant and Cell Physiology 2013-06-12
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