A5048540388- Per- and polyfluoroalkyl substances research
- Muscle and Compartmental Disorders
- Effects and risks of endocrine disrupting chemicals
- Toxic Organic Pollutants Impact
- Pluripotent Stem Cells Research
- MicroRNA in disease regulation
- Mesenchymal stem cell research
- Neurogenesis and neuroplasticity mechanisms
- interferon and immune responses
- Food composition and properties
- Electrolyte and hormonal disorders
- Technology Assessment and Management
- Cardiac pacing and defibrillation studies
- Vitamin C and Antioxidants Research
- Cytokine Signaling Pathways and Interactions
- Methemoglobinemia and Tumor Lysis Syndrome
- Rice Cultivation and Yield Improvement
- Cardiac Imaging and Diagnostics
- Kruppel-like factors research
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Heat shock proteins research
- Poisoning and overdose treatments
- CRISPR and Genetic Engineering
- Cardiac Arrest and Resuscitation
Queen's University Belfast
1985-2025
Stanford University
2020
Howard Hughes Medical Institute
2020
Freeman Hospital
2014
Royal Victoria Eye and Ear Hospital
1982-1985
A Bangladesh village rice parboiling plant was used to investigate how improve essential elements and B-vitamin content of rice, while reducing the toxicants arsenic cadmium, potential bacterial pathogens. 25 -factorial experiment conducted where husked de-husked parboiled at different pre-parboiling soaking times, temperatures, through either boiling or steaming, for 2 times. Three cultivars were used. Using wholegrain, rather than rough with 15 mins parboiling, gave optimal reduction in...
Serum myoglobin concentration and creatine kinase activity were measured serially in 70 consecutive patients presenting within four hours of the onset symptoms suspected acute myocardial infarction. Of 36 with definite or possible infarction (WHO criteria), serum was raised (greater than 85 micrograms/l) one hour after 25% at 89%. Creatine 140 U/l) only 56%. Within 12 reached a peak 83% 14%. fell to normal values 67% while 3%. Four distinguished easily those from without, whereas when used...
Human exposure to persistent organic pollutants (POPs) has been linked genitourinary health-related conditions such as decreased sperm quality, hypospadias, and prostate cancer (PCa). Conventional risk assessment of POPs focuses on individual compounds. However, in real life, individuals are exposed many compounds simultaneously. This might lead combinatorial effects whereby the global effect mixture is different from single elements or subgroups. POP mixtures may act endocrine disruptors...
Abstract Perfluoroalkyl acids (PFAAs) are detectable in human blood. PFAA exposure may contribute to androgen receptor (AR)-related health effects such as prostate cancer (PCa). In Norway and Sweden, exposures PFAAs PCa very real concerns. vitro studies conventionally do not investigate PFAA-induced AR disruption at blood-based concentrations, thus limiting application health. We aim determine the endocrine disrupting activity of based upon levels, on transactivation translocation. (PFOS,...
Study of 80 consecutive patients undergoing elective diagnostic cardiac catheterisation showed that after the procedure 25 (31%) developed myoglobinaemia. This was attributed to complications in two. The remaining 23 had received premedication by intramuscular injection. In without injections myoglobinaemia did not occur uncomplicated catheterisation. study support proposition results myocardial damage which can be detected abnormalities myoglobin but conventional indications necrosis.
Aim: A scoring system derived from MADIT 2 used 5 clinical factors; Age >70 years, QRS >120msec, atrial fibrillation (AF), NYHA > II and blood urea nitrogen (BUN) 26mg/dL to predict risk in primary prevention ICD recipients with ischaemic heart disease (IHD). Patients whose score was either 0 or ≥ 3 received no benefit an ICD. The purpose of this retrospective, observational study determine how a patient's changes time initial insertion first generator change. Method: Consecutive patients...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Abstract Understanding the impact of radiotherapy on evolution treatment resistant prostate cancer is critical for selecting effective combinations. Whilst activation Type 1 interferon signalling a hallmark how cells respond to viral infection, in cells, multiple stresses are known activate this same response. In study we have evaluated first time changes response induced by culturing under sphere- forming conditions and following irradiation. We report conserved upregulated transcript...