A5002921425- Forensic Toxicology and Drug Analysis
- Cannabis and Cannabinoid Research
- HIV/AIDS drug development and treatment
- Psychedelics and Drug Studies
- Analytical Chemistry and Chromatography
- HIV Research and Treatment
- HIV/AIDS Research and Interventions
- Mass Spectrometry Techniques and Applications
- Analytical chemistry methods development
- Health and Medical Studies
- Metabolomics and Mass Spectrometry Studies
- Inhalation and Respiratory Drug Delivery
- Carcinogens and Genotoxicity Assessment
- Sulfur-Based Synthesis Techniques
- Pneumocystis jirovecii pneumonia detection and treatment
- Synthesis and biological activity
- Oxidative Organic Chemistry Reactions
- Biochemical and biochemical processes
- Synthesis and Characterization of Heterocyclic Compounds
- Opioid Use Disorder Treatment
- Neurotransmitter Receptor Influence on Behavior
- Pesticide Residue Analysis and Safety
- GABA and Rice Research
- Synthesis of heterocyclic compounds
- Organic Chemistry Cycloaddition Reactions
Laboratoire National de Santé
2011-2025
Philipps University of Marburg
2025
University of Cologne
2019
The University of Queensland
2018
University of Mannheim
2008-2015
Heidelberg University
2008-2015
University of Luxembourg
2004-2014
Médecins Sans Frontières
2014
Charité - Universitätsmedizin Berlin
2010
BG University Hospital Bergmannsheil Bochum
2009
Highly active antiretroviral therapy with efavirenz (EFV) has been prescribed to HIV-positive pregnant women in Rwanda (HIV status 1 and CD4 cell count > 350 cells/mm) during the last trimester of pregnancy for 6 months after delivery. The EFV concentrations maternal plasma, breast milk newborns' plasma 13 their children between weeks post partum are reported.Results show a mean concentration 6.55 mg/L 3.51 skim milk, 0.85 infant plasma. Significant linear correlations (r = 0.8666, P <...
Illicit drug use presents a significant challenge to global health and public safety, requiring innovative effective monitoring strategies. This study aimed evaluate the current landscape of wastewater-based epidemiology (WBE) for illicit drugs in Europe, focusing on collaboration, practices, barriers, while identifying opportunities improvement. Cross-sectional survey-based study. Coordinated by Sewage Analysis CORe Group Europe (SCORE) European Union Drugs Agency (EUDA), two surveys were...
The aim of this study was to screen seized illegal cannabis plants for pesticides. Cannabis samples were analysed according the EN 15662 method. Pesticides detected with UPLC/MS-MS in positive ESI mode using multiple reaction monitoring and GC-MS scan mode. A total 50 tested 160 different Seven pesticides 19 five contained two Four fungicides (propamocarb, tebuconazole, propiconazole tolylfluanid). other 3 insecticides or acaricides (imidacloprid, bifenthrin, hexythiazox).
Fentanyl is a synthetic opioid used to treat intense chronic pain. In this study, the authors report detection and quantification of fentanyl in sweat hair patient receiving (25 microg/h) via transdermal therapeutic system (TTS) for 22 days. Sweat was collected using patches every night on days 13-21 therapy, 12 weeks after end treatment. Detection performed with liquid chromatography-tandem mass spectrometry electron spray ionization selected reaction monitoring mode. Alfentanyl as internal...
The aim of this study was to evaluate the effect UGT1A1 polymorphisms on Raltegravir (RAL) and its metabolite RAL-glucuronide trough plasma concentrations ([RAL]plasma [RAL-glu]plasma) metabolic ratio (MR): [RAL-glu]plasma/[RAL]plasma. genotyping performed 96 patients. 44% (n = 42) were homozygous UGT1A1*1/*1 while 50% 48) 6% 6) UGT1A1*28 UGT1A1*36 carriers, respectively. median concentration interquartile range (IQR) [RAL]plasma 88.5 ng/ml (41.0-236), 168 (85.8-318) 92.5 (36.4-316) for...
Background North West Pakistan is an area ravaged by conflict and population displacement for over three decades. Recently, drone attacks military operations have aggravated underlying mental disorders, while access to care limited. Among patients attending a health clinic integrated in district hospital conducted psychologists; we describe service utilization, patient characteristics, presenting complaints, morbidity patterns, follow-up details. Methodology/Principal Findings A...
Introduction: Anticonvulsant drugs are increasingly being used for alcohol detoxification in in- and outpatient settings. The aim of this study was to examine the efficacy, medical safety mid-term outcome levetiracetam, a drug with no marked liver toxicity, detoxification.
Abstract Background Drug consumption rooms offer heroin and cocaine consumers a secure hygienic environment including medical social guidance. Despite the support mentoring, only sparse information is available about how drug quality, prices user expectations match at these locations. The present study reports analysis of three parameters in two Luxembourg. Methods users were invited to participate project by handing few milligrams product they planned consume for chemical filling out short...
We evaluated a new test device for amphetamines and methamphetamines (Frontline ® , cut-off limit 300 ng/mL) using authentic clinical forensic specimens. The is based on immunochromatography dipped into urine read visually by comparison with colour scale after few minutes. A total of 658 specimens were tested comparing results the screening procedure established immunoassays. Discordant further investigated gas chromatography- mass spectrometry or chromatography (with flame ionization...