A5086564464- Advanced Radiotherapy Techniques
- Radiation Therapy and Dosimetry
- Management of metastatic bone disease
- Glioma Diagnosis and Treatment
- Radiation Dose and Imaging
- Colorectal Cancer Surgical Treatments
- Ear and Head Tumors
- Brain Metastases and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Head and Neck Surgical Oncology
- Radiation Detection and Scintillator Technologies
- CAR-T cell therapy research
- Radiation Effects and Dosimetry
- Head and Neck Cancer Studies
- Advanced X-ray and CT Imaging
- Breast Cancer Treatment Studies
- Lung Cancer Diagnosis and Treatment
- Immunotherapy and Immune Responses
- Cancer Immunotherapy and Biomarkers
- Hepatocellular Carcinoma Treatment and Prognosis
- Vascular Tumors and Angiosarcomas
- Sarcoma Diagnosis and Treatment
- RNA Interference and Gene Delivery
- Medical Imaging Techniques and Applications
- Prostate Cancer Treatment and Research
Hospital Universitari Arnau de Vilanova
2025
Hospital Arnau de Vilanova
2023
Clinica Universidad de Navarra
2012-2022
Universidad de Navarra
2005-2022
Universidad Fernando Pessoa Canarias
2020
Vall d'Hebron Institute of Oncology
2020
Navarre Institute of Health Research
2015-2019
To compare target dose distribution, comformality, normal tissue avoidance, and irradiated body volume (IBV) in 3DCRT using classic anatomical landmarks (c3DCRT), fitting the PTV (f3DCRT), intensity-modulated radiation therapy (IMRT) patients with locally advanced rectal cancer (LARC). Fifteen LARC underwent c3DCRT, f3DCRT, IMRT planning. Target definition followed recommendations of ICRU reports No. 50 62. OAR (SB bladder) constraints were D5 ≤ Gy Dmax < 55 Gy. prescription was defined as...
Abstract Pediatric high-grade glioma (pHGG) and diffuse intrinsic pontine gliomas (DIPGs) are aggressive pediatric brain tumors in desperate need of a curative treatment. Oncolytic virotherapy is emerging as solid therapeutic approach. Delta-24-RGD replication competent adenovirus engineered to replicate tumor cells with an aberrant RB pathway. This virus has proven be safe effective adult gliomas. Here we report that the administration mice results significant increase survival...
The purpose of this work is to present a new method extract the electron density ([Formula: see text]) and effective atomic number (Z eff) from dual-energy CT images, based on Karhunen-Loeve expansion (KLE) cross section per electron. This was used calibrate Siemens Definition using CIRS phantom. predicted 80 kVp 140 were compared with calibration phantom an independent set samples. mean absolute deviations between theoretical calculated values for all samples 1.7 % ± 0.1 [Formula: text] 4.1...
Purpose: An improved method for multichannel dosimetry is presented. This explicitly takes into account the information provided by unexposed image of film. Methods: The calculates dose applying a couple perturbations to scanned dose, one dependent and other independent on color channel. has been compared with previous two single channel methods (red green) against measurements using different tests: first, five percentage depth profiles covering wide range doses; second, map perpendicular...
Abstract: Vertebral compression fractures (VCFs) are common in multiple myeloma (MM). Percutaneous vertebroplasty (PVP) is used to stabilize vertebral collapse and treat the pain. Few studies have been carried out on PVP MM follow‐up has tended be short. We prospectively evaluated safety efficacy of VCFs resulting from or plasmacytomas. Nineteen were performed 12 consecutive patients. monitored their pain functional status using visual analog (VAS) Eastern Cooperative Oncology Group (ECOG)...
To demonstrate the feasibility of characterising MLCs and MLC models implemented in TPSs using a common set dynamic beams. A tests containing synchronous (SG) asynchronous sweeping gaps (aSG) was distributed among twenty-five participating centres. Doses were measured with Farmer-type ion chamber computed TPSs, which provided dosimetric characterisation leaf tip, tongue-and-groove, transmission each MLC, as well an assessment model TPS. Five types four evaluated, covering most frequent...
Full-dose postoperative external beam radiation therapy (EBRT)/chemoradiation is the standard of care in patients with resected, unirradiated head and neck cancer (HNC). This study aims to determine long-term results adjuvant high-dose rate (HDR) brachytherapy ± intermediate-dose this HNC patient population. From 2000 2018, a total 152 diagnosed were treated surgery HDR alone (n = 32) or combined EBRT chemotherapy 120). Patients received 32 40 Gy 8 10 b.i.d. fractions. Combined modality 16...
Purpose: To compare how the inclusion of uncertainties in dose and optical density affects results calibration Gafchromic ® EBT3 radiochromic films. Methods: Five methods least square minimization were compared for These differed way which are taken into account. The comparison was made by simulating fit at an increasing number points measured table gamma analysis ten real IMRT verifications. Results: According to simulations, that take account all variability superior those do not use them....
Introduction: Fatigue is one of the most frequent symptoms in patients with cancer. No adequate term Spanish has been defined to describe English concept fatigue. Aim: To identify suitable words that define fatigue and check psychometric characteristics. Method: Consensus professional experts on best suit A prospective study oncologic was also undertaken, which included an evaluation intensity through visual numeric scales (VNS) where had previously selected. The subscale Functional...
Background Hypofractionated radiation therapy is a feasible and safe treatment option in elderly frail patients with glioblastoma. The aim of this study was to evaluate the effectiveness hypofractionated concurrent temozolomide terms feasibility disease control primary glioblastoma poor prognostic factors other than advanced age, such as post-surgical neurological complications, high tumor burden, unresectable or multifocal lesions, potential low compliance due social rapidly progressive...
Multicatheter breast brachytherapy is a standard technique for accelerated partial irradiation (APBI) in early cancer patients. Intraoperative multicatheter implant (IOMBI) followed by perioperative high-dose-rate (PHDRBT) offers novel and advantageous approach. We present long-term oncological, toxicity, cosmesis outcomes well-experienced single institution.
The double-stacked design of the Halcyon multileaf collimator (MLC) presents new challenges for treatment planning systems (TPSs). leaf trailing effect has recently been described as result interplay between fluence transmitted through tip ends each MLC layer. This makes dosimetric gap (DLG) dependent on distance leaves different layers (trailing distance) and is not adequately modeled by Eclipse TPS. purpose our study was to investigate report dose discrepancies produced these limitations...