A5058526750- vaccines and immunoinformatics approaches
- Monoclonal and Polyclonal Antibodies Research
- SARS-CoV-2 and COVID-19 Research
- Immunotherapy and Immune Responses
- Salivary Gland Disorders and Functions
- Extracellular vesicles in disease
- Bacteriophages and microbial interactions
- RNA Interference and Gene Delivery
- Antibiotic Resistance in Bacteria
- Mesenchymal stem cell research
- Toxin Mechanisms and Immunotoxins
- MicroRNA in disease regulation
- Cancer-related gene regulation
- Peptidase Inhibition and Analysis
- Wnt/β-catenin signaling in development and cancer
- Glycosylation and Glycoproteins Research
- RNA and protein synthesis mechanisms
- Bacterial Genetics and Biotechnology
- Transgenic Plants and Applications
- Animal Virus Infections Studies
- Cancer Immunotherapy and Biomarkers
- SARS-CoV-2 detection and testing
- Computational Drug Discovery Methods
- COVID-19 Clinical Research Studies
- Immune Cell Function and Interaction
Shahid Rajaee Teacher Training University
2018-2025
Universitat Rovira i Virgili
2024
Tarbiat Modares University
2011-2021
Iran University of Medical Sciences
2021
Mashhad University of Medical Sciences
2021
Baqiyatallah University of Medical Sciences
2017-2020
University of Bonab
2018-2019
Dezful University of Medical Sciences
2017
McGill University
2006-2014
Islamic Azad University, Tehran
2009
Immunoinformatics is a new critical field with several tools and databases that conduct the eyesight of experimental selection facilitate analysis great amount immunologic data obtained from researches helps to design introducing hypothesis. Given these visages, immunoinformatics seems be way develop progress immunological research. Bioinformatics methods applications are successfully employed in vaccine informatics assist different sites preclinical, clinical, post-licensure enterprises. On...
There are reports that bone marrow cell (BM) transplants repaired irradiated salivary glands (SGs) and re-established saliva secretion. However, the mechanisms of action behind these have not been elucidated.To test if a paracrine mechanism was main effect this reported improvement in organ function, whole BM cells were lysed its soluble intracellular contents (termed as "BM Soup") injected into mice with irradiation-injured SGs. The hypothesis Soup would protect cells, increase tissue...
Background Non-obese diabetic (NOD) mice develop Sjögren's-like disease (SS-like) with loss of saliva flow and increased lymphocytic infiltrates in salivary glands (SGs). There are recent reports using multipotent mesenchymal stromal cells (MSCs) as a therapeutic strategy for autoimmune diseases due to their anti-inflammatory immunomodulatory capabilities. This paper proposed combined immuno- cell-based therapy consisting of: A) an injection complete Freund's adjuvant (CFA) eradicate...
Acinetobacter baumannii is a serious health threat with high mortality rate. We have already reported prophylactic effects of IgYs raised against OmpA and Omp34 as well inactivated whole-cell (IWC) A. in murine pneumonia model. However, the infection was exacerbated mice group that received combination Omp34. The current study conducted to propose reasons for observed antibody-dependent enhancement (ADE) addition therapeutic effect specific This phenomenon hypothetically attributed...
Aim: We investigated the delivery of sorafenib (SFB) to breast cancer spheroids by natural killer cell-derived exosomes (NK-Exos). Methods: SFB-NK-Exos were constructed electroporation. Their antitumor effects evaluated methyl thiazolyl tetrazolium, acridine orange/ethidium bromide, 4′,6-diamidino-2-phenylindole, annexin/propidium iodide, scratch and migration assay, colony formation, RT-PCR, western blot lipophagy tests. Result: The loading efficacy was 46.66%. SFB-NK-Exos-treated showed...
Introduction This study aimed to assess the expression changes of BTG1, PGI, and PGII in tissues serum patients with gastric cancer, atrophic gastritis, healthy individuals.
Human immune system includes variety of different cells and molecules correlating with other body systems. These instances complicate the analysis system; particularly in postgenomic era by introducing more amount data, complexity is increased necessity using computational approaches to process interpret them tangible.Immunoinformatics as a subset bioinformatics new approach tools databases that facilitate enormous immunologic data obtained from experimental researches. In addition directing...
Autoimmune diseases (ADs) could occur due to infectious and vaccination programs. Since millions of people are expected be infected with SARS-CoV-2 vaccinated against it, autoimmune consequences seem inevitable. Therefore, we have investigated the whole proteome for its ability trigger ADs. In this regard, entire was chopped into more than 48000 peptides. The produced peptides were searched human find shared similar experimentally confirmed T-cell B-cell epitopes. obtained checked their bind...
Abstract Non-informatics cost estimation is a tedious process and requires substantial amount of time manual operations. However, BIM adoption approaches have attracted significant attention with this respect. Since models are object-based built-in parametric information, it easier to capture the quantities building elements deliver more accurate estimates less errors omissions. As most current standards designed developed based on old-fashioned construction project delivery systems, lack...