A5077392773- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Crystallography and molecular interactions
- Semiconductor Lasers and Optical Devices
- Photonic and Optical Devices
- Advanced Fiber Laser Technologies
- Spectroscopy Techniques in Biomedical and Chemical Research
- Terahertz technology and applications
- Crystal structures of chemical compounds
- Analytical Chemistry and Chromatography
- Planetary Science and Exploration
- Cultural Heritage Materials Analysis
- Spectroscopy and Chemometric Analyses
- Chemical Thermodynamics and Molecular Structure
- Nanoplatforms for cancer theranostics
- Identification and Quantification in Food
- Paleontology and Stratigraphy of Fossils
- Electrocatalysts for Energy Conversion
- Analytical Methods in Pharmaceuticals
- Advanced Chemical Sensor Technologies
- Spectroscopy and Laser Applications
- Isotope Analysis in Ecology
- Supercapacitor Materials and Fabrication
- Polymer Synthesis and Characterization
- SARS-CoV-2 detection and testing
University of Lincoln
2016-2024
Philipps University of Marburg
2018-2021
Aarhus University
2021
TD Bank
2018-2020
University of Bradford
2005-2014
Abstract The rapid identification for drugs‐of‐abuse in airports is of critical importance. In this study we demonstrate the viability Raman spectroscopy illicit substances their containers an airport environment. spectra situ were collected using portable spectrometers; technique offers distinct advantages to government agencies, first responders and forensic scientists working security field. We have demonstrated that spectrometers are able collect suspect powders, including cocaine HCl d...
Abstract Surface side reactions and time‐consuming modification methods hinder the practical application of zinc‐ion batteries. This study introduces an ultrathin protection layer for Zn anode via a rapid sputtering method. The dopants on CN10@Zn create surface dipoles local variations in charge distribution, facilitating zinc ion migration to pyrrolic nitrogen dopant sites with reduced adsorption barriers. Additionally, hydroxyl oxygen enhance hydrophilicity layer, forming strong adhesion...
Cocrystals have been increasingly recognized as an attractive alternative delivery form for solids of drug products. In this work, salicylic acid was employed a cocrystal former with the nicotinic acid, dl-phenylalanine, and 6-hydroxynicotinic (6HNA). Also, 3,4-dihydroxybenzoic oxalic studied. The cocrystals in all cases were prepared by slow evaporation from ethanol followed characterization using Raman spectroscopy, powder X-ray diffraction, transmission spectroscopy (TRS), differential...
Terahertz frequency time-domain spectroscopy has been used to analyse a wide range of samples containing cocaine hydrochloride, heroin and ecstasy – common drugs-of-abuse. We investigated real-world seized by law enforcement agencies, together with pure drugs-of-abuse, drugs-of-abuse systematically adulterated in the laboratory emulate samples. In order investigate feasibility automatic spectral recognition such illicit materials terahertz spectroscopy, principal component analysis was...
The design of a melt synthesis the first air-stable formulation metastable form III paracetamol is derived from thermo-spectroscopic and thermo-diffraction experiments. Melt crystallisation in presence β-1,4-saccharides produces selectively excipients appear to act as stabilising 'active' templates polymorph.
Multidrug resistant bacterial infection remains a significant public concern. In this report, photosensitizer Chlorin e6 doped silica was synthesized. This hybrid structure exhibits enhanced photostability and high antibacterial efficiency towards Staphylococcus aureus (S. aureus) methicillin-resistant S. (MRSA). summary, work demonstrates an effective platform to improve the of antibiotics for better treatment wound infections.
Cocrystals have been increasingly recognized as an attractive alternative delivery form for solid drug products. In this work, Raman spectroscopy, X-ray powder diffraction/X-ray crystallography, and differential scanning calorimetry used to study the phenomenon of cocrystal formation in stoichiometric mixtures citric acid with paracetamol. spectroscopy was particularly useful characterization products determine nature interactions cocrystals. It observed that little change vibrational modes...
Abstract Four new ternary crystalline molecular complexes have been synthesised from a common 3,5‐dinitrobenzoic acid (3,5‐dnda) and 4,4′‐bipyridine (bipy) pairing with series of amino‐substituted aromatic compounds (4‐aminobenzoic (4‐aba), 4‐( N , ‐dimethylamino)benzoic (4‐dmaba), 4‐aminosalicylic (4‐asa) sulfanilamide (saa)). The crystals were created through the application complementary charge transfer hydrogen‐bonding interactions. For these systems dimer was charge‐transfer interaction...
Abstract The laser excitation wavelength is an important parameter in obtaining Raman spectra from drugs‐of‐abuse. This article compares the effect of near infrared wavelengths, 785 nm, using both benchtop and portable instrumentation 1064 nm on seized drugs‐of‐abuse, including cocaine hydrochloride, freebase (crack), methylenedioxymethamphetamine (‘ecstasy’), amphetamine, diamorphine (heroin) cannabis. significant benefit for interrogation this type sample highlighted. Copyright © 2009 John...
The efficiency of reduced volume PCR amplification was studied using the VeriFiler™ Express Amplification Kit. Full (25 μL) and (5 volumes were tested in parallel to identify any differences template DNA sensitivity other electropherogram parameters. Both produced full profiles down 0.08 ng/μL concentration at 26 cycles; however, higher peak heights due increased signal intensities. Significant difference (p-value ≤ 0.05) heterozygote height ratios observed between both volumes, where...
Recently, cocaine has been concealed by dissolving it in alcohol and then transporting solution through ports airports. At the present time is very difficult to detect this form these environments. However, shown that Raman spectroscopy can successfully presence of drugs without removing specimens from their containers. Using two portable 785 nm instruments a 1064 laboratory‐based instrument, several common containers used smuggling were analyzed with varying concentrations ethanol...
Abstract Gamma hydroxybutyric acid (GHB), also known as ‘liquid ecstasy’, has recently become associated with drug‐facilitated sexual assaults, colloquially ‘date rape’, due to the ability of drug cause loss consciousness. The is commonly found ‘spiked’ into alcoholic beverages, alcohol increases its sedative effects. and corresponding lactone gamma‐butyrolactone (GBL) will reach an equilibrium in solution which favours basic conditions GHB acidic (less than pH 4). Therefore, we have studied...
Abstract In this paper, we demonstrate the ability of portable Raman spectroscopy and benchtop spatially offset (SORS) techniques to rapidly identify real fake ivory samples. Both were able exposed genuine from contrast conventional spectroscopy, SORS was, in addition, concealed by plastics, paints, varnishes cloth. Application technique allows interrogation biomaterial samples through materials which spectroscopic instrumentation cannot penetrate. Copyright © 2009 John Wiley & Sons, Ltd.
Six new multi-component crystals between 4-phenylpyridine and substituted benzoic acids (3-nitrobenzoic acid, 3,5-dinitrobenzoic gallic 4-aminobenozic salicylic acid 2-aminobenzoic acid) were created characterized crystallographically to investigate the influence of chemical structural factors on hydrogen location two components. While expected intermolecular interactions are formed pyridine group in most cases, structure is anomalous forming an unexpected salt with hydroxyl interactions....