A5081801883- Ion Channels and Receptors
- Intensive Care Unit Cognitive Disorders
- Anesthesia and Sedative Agents
- Essential Oils and Antimicrobial Activity
- Anesthesia and Neurotoxicity Research
- Food Allergy and Anaphylaxis Research
- Skin and Cellular Biology Research
- Cardiac Ischemia and Reperfusion
- Advanced MRI Techniques and Applications
- MRI in cancer diagnosis
- Phytochemicals and Antioxidant Activities
- Tryptophan and brain disorders
- Polyamine Metabolism and Applications
- Contact Dermatitis and Allergies
- Adipose Tissue and Metabolism
- Infrared Thermography in Medicine
- Neuroscience and Neuropharmacology Research
- Cardiovascular Function and Risk Factors
- Lanthanide and Transition Metal Complexes
- Muscle Physiology and Disorders
- Cardiac Arrest and Resuscitation
- Pharmacological Receptor Mechanisms and Effects
- Extracellular vesicles in disease
- Herbal Medicine Research Studies
Stanford Medicine
2025
Stanford University
2020-2024
Instituto Butantan
2024
United States Patent and Trademark Office
2021
Teleflex (United States)
2021
Barro Colorado Island
2021
Second Hospital of Anhui Medical University
2020
Anhui Medical University
2020
Case Western Reserve University
2014-2015
Nicotinamide Adenine Dinucleotide (NAD+) is implicated in bioenergetics, DNA repair, and senescence. Depletion of NAD+ associated with aging neurodegenerative disease, prompting a growing interest supplementation. With rising over-the-counter use NAD, understanding their impact on anesthetic recovery becomes essential. This study investigates the effect NADH, common precursor, anesthesia rodents. Baseline post-anesthesia (1.5% isoflurane) open field Y-maze activity were recorded adult male...
Arterial spin labeling (ASL) is a valuable non‐contrast perfusion MRI technique with numerous clinical applications. Many previous ASL studies have utilized either echo‐planar imaging (EPI) or true fast steady‐state free precession (true FISP) readouts, which are prone to off‐resonance artifacts on high‐field scanners. We developed rapid ASL‐FISP acquisition for preclinical scanners providing perfusion‐weighted images little no in less than 2 s. In this initial implementation, flow‐sensitive...
Dystrophin, the main component of dystrophin–glycoprotein complex, plays an important role in maintaining structural integrity cells. It is also involved formation blood–brain barrier (BBB). To elucidate impact dystrophin disruption vivo, we characterized changes cerebral perfusion and diffusion dystrophin-deficient mice (mdx) by magnetic resonance imaging (MRI). Arterial spin labeling (ASL) diffusion-weighted MRI (DWI) studies were performed on 2-month-old 10-month-old mdx their age-matched...
Nicotinamide Adenine Dinucleotide (NAD
Heart disease is the leading cause of death in Asian Americans. Importantly, people East descent are more likely to carry a loss-of-function point mutation aldehyde dehydrogenase 2 (ALDH2), ALDH2*2, which reduces ALDH2 enzymatic activity by at least 40% relative wild type ALDH2. Given role removing toxic aldehydes from cell, intimately involved cardioprotective mechanisms ischemic preconditioning and pathophysiology ischemia reperfusion injury. The ALDH2*2 variant associated with an...
Gamma-aminobutyric acid (GABA) is a major inhibitory neurotransmitter within the brain regulating neuronal excitability through family of GABA receptors including GABAA. Despite preclinical evidence, GABAA receptor agonists are antinociceptive ([Kendall et al., 1982][1]; [Malan 2002][2])
Airway management of adult patients with recessive dystrophic epidermolysis bullosa presents significant challenges associated tissue fragility and distortion airway anatomy. This retrospective case series describes 11 difficult airways undergoing 24 general anesthetics in which transnasal humidified rapid-insufflation ventilatory exchange was used for preoxygenation apneic oxygenation. Despite an average time to intubation over 6 minutes, provided oxygenation before endotracheal without the...