Emrah Kırdök

ORCID: 0000-0003-0500-1208
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About
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Research Areas
  • Forensic and Genetic Research
  • Forensic Anthropology and Bioarchaeology Studies
  • Dental Health and Care Utilization
  • Archaeology and ancient environmental studies
  • Yersinia bacterium, plague, ectoparasites research
  • Environmental DNA in Biodiversity Studies
  • Genomics and Phylogenetic Studies
  • Metabolomics and Mass Spectrometry Studies
  • Bone and Dental Protein Studies
  • Dental Radiography and Imaging
  • Archaeology and Historical Studies
  • Plant and Fungal Interactions Research
  • Metallurgy and Cultural Artifacts
  • Research on scale insects
  • Zoonotic diseases and public health
  • Genetic diversity and population structure
  • Ancient Near East History
  • Silkworms and Sericulture Research
  • Oral microbiology and periodontitis research
  • Bioenergy crop production and management
  • Urological Disorders and Treatments

General Directorate of Forestry
2022-2024

Mersin Üniversitesi
2021-2024

Centre for Palaeogenetics
2021

Stockholm University
2018-2019

Analysis of microbial data from archaeological samples is a growing field with great potential for understanding ancient environments, lifestyles, and diseases. However, high error rates have been challenge in metagenomics, the availability computational frameworks that meet demands limited. Here, we propose aMeta, an accurate metagenomic profiling workflow DNA designed to minimize amount false discoveries computer memory requirements. Using simulated data, benchmark aMeta against current...

10.1186/s13059-023-03083-9 article EN cc-by Genome biology 2023-10-23

Abstract Human demography research in grounded on the information derived from ancient DNA and archaeology. For example, study early postglacial dual-route colonisation of Scandinavian Peninsula is largely based associating genomic data with dispersal lithic technology East European Plain. However, a clear connection between material culture genetics has been lacking. Here, we demonstrate that direct by analysing human chewed birch bark pitch mastics. These samples were discovered at Huseby...

10.1038/s42003-019-0399-1 article EN cc-by Communications Biology 2019-05-15

We present a spatiotemporal picture of human genetic diversity in Anatolia, Iran, Levant, South Caucasus, and the Aegean, broad region that experienced earliest Neolithic transition emergence complex hierarchical societies. Combining 35 new ancient shotgun genomes with 382 23 present-day published genomes, we found within each steadily increased through Holocene. further observed inferred sources gene flow shifted time. In first half Holocene, Southwest Asian East Mediterranean populations...

10.1016/j.cub.2022.11.034 article EN cc-by Current Biology 2022-12-08

Prehistoric chewed pitch has proven to be a useful source of ancient DNA, both from humans and their microbiomes. Here we present the metagenomic analysis three pieces Huseby Klev, Sweden, that were dated 9,890-9,540 before present. The profile exposes Mesolithic oral microbiome includes opportunistic pathogens. We compared data with healthy dysbiotic datasets identified increased abundance periodontitis-associated microbes. In addition, trained machine learning models predicted dysbiosis...

10.1038/s41598-023-48762-6 article EN cc-by Scientific Reports 2024-01-18

Abstract Arguments have long suggested that the advent of early farming in Near East and Anatolia was linked to a ‘Mother Goddess’ cult. However, evidence for dominant female role these societies has been scarce. We studied social organisation, mobility patterns gendered practices Neolithic Southwest Asia using 131 paleogenomes from Çatalhöyük Mound (7100-5950 BCE), major settlement Central with an uninterrupted occupation apparent egalitarian structure. In contrast widespread genetic...

10.1101/2024.06.23.600259 preprint EN cc-by-nc bioRxiv (Cold Spring Harbor Laboratory) 2024-06-24

Wild cherry (Prunus avium L, syn. Cerasus L. Moench.) is a widely spread forest tree that has ecological and economical importance. However, the genetic diversity of this species threatened for many reasons. Therefore, breeding conservation program should be established in order to minimise loss diversity. In study, we aimed understand structure 440 individual wild cherries sampled from 22 different populations Turkey using 10 SSR molecular markers. With variance analysis, found within...

10.3906/bot-2111-16 article EN TURKISH JOURNAL OF BOTANY 2022-01-01

Abstract With the Neolithic transition, human lifestyle shifted from hunting and gathering to farming. This change altered subsistence patterns, cultural expression, population structures as shown by archaeological/zooarchaeological record, well stable isotope ancient DNA data. Here, we used metagenomic data analyse if transitions also impacted microbiome composition in 25 Mesolithic hunter-gatherers 13 farmers several Scandinavian Stone Age contexts. Salmonella enterica, a bacterium that...

10.1038/s41598-024-56096-0 article EN cc-by Scientific Reports 2024-03-07

Abstract Analysis of microbial data from archaeological samples is a rapidly growing field with great potential for understanding ancient environments, lifestyles and disease spread in the past. However, high error rates have been long-standing challenge metagenomics analysis. This also complicated by limited choice microbiome specific computational frameworks that meet demands field. Here, we propose aMeta, an accurate Metagenomic profiling workflow designed primarily to minimize amount...

10.1101/2022.10.03.510579 preprint EN cc-by-nd bioRxiv (Cold Spring Harbor Laboratory) 2022-10-05

Abstract The Middle East plays a central role in human history harbouring vast diversity of ethnic, cultural and religious groups. However, much remains to be understood about past present genomic this region. Here we multidisciplinary bioarchaeological analysis two individuals dated the late 7th early 8th centuries, Umayyad Era, from Tell Qarassa, an open-air site modern-day Syria. Radiocarbon dates burial type are consistent with one earliest Islamic Arab burials Levant. Interestingly,...

10.1038/s42003-022-03508-4 article EN cc-by Communications Biology 2022-06-07

Abstract Burial customs in the Iberian Period (Iron Age II) included cremation. Only perinatal and newborn infants were buried directly beneath floor settlement. These represent very few unburned human remains recovered from sites. The interpretation of these infant burials is debate, focusing on whether they are unnatural or natural deaths. Our aim to infer mortality patterns developmental conditions individuals, order respond if infanticide was present assemblages. A large skeletal sample...

10.1007/s12520-023-01863-9 article EN cc-by Archaeological and Anthropological Sciences 2023-10-01

The white poplar (Populus alba L.), which is tolerant to abiotic and biotic stresses, a tree species that resilient against changing climatic environmental conditions, makes it suitable candidate for afforestation efforts. However, due prolonged human intervention associated with the increasing population, genetic resources of this are at risk loss. Additionally, while generally reproduces sexually, reproduction clonally via its root suckers has become widespread in some areas. Hence, aim...

10.55730/1300-008x.2790 article EN TURKISH JOURNAL OF BOTANY 2024-01-16

The discussion of an early postglacial dual-route colonization the Scandinavian Peninsula is largely based on associating genomic data to dispersal lithic technology from East European Plain. However, a direct link between two has been lacking. We tackle this problem by analysing human DNA birch bark pitch mastics, “chewing gums”, Huseby Klev, site in western Sweden with eastern technology. generate genome- wide for three individuals, and show their affinity hunter-gatherers, or more...

10.1101/485045 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2018-12-03
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