A5107993749- Pregnancy and preeclampsia studies
- Birth, Development, and Health
- Maternal and fetal healthcare
- Gestational Diabetes Research and Management
- Reproductive Health and Contraception
- Ectopic Pregnancy Diagnosis and Management
- Neonatal Respiratory Health Research
- Electrolyte and hormonal disorders
- Human Health and Disease
- Maternal and Perinatal Health Interventions
- Pregnancy and Medication Impact
- Global Maternal and Child Health
- Neonatal and fetal brain pathology
- Adrenal Hormones and Disorders
- Folate and B Vitamins Research
- Delphi Technique in Research
- Epilepsy research and treatment
- Prenatal Screening and Diagnostics
- Preterm Birth and Chorioamnionitis
- Fetal and Pediatric Neurological Disorders
- Health, Environment, Cognitive Aging
- Infant Development and Preterm Care
- Pharmacological Effects and Toxicity Studies
- Assisted Reproductive Technology and Twin Pregnancy
University of British Columbia
2011-2024
British Columbia Children's Hospital
2020-2024
B.C. Women's Hospital & Health Centre
2023
Meta-analyses of observational studies have shown that women with a shorter interpregnancy interval (the time from delivery to start subsequent pregnancy) are more likely experience adverse pregnancy outcomes, such as preterm or small for gestational age birth, than who space their births further apart. However, the used inform these estimates methodological shortcomings.In this commentary, we summarise discussions an expert workgroup describing good practices design, analysis, and...
Abstract Background The World Health Organization ( WHO ) recommends that women wait at least 24 months after a livebirth before attempting subsequent pregnancy to reduce the risk of adverse maternal, perinatal, and infant health outcomes. However, applicability recommendations for in United States is unclear, as breast feeding, nutrition, maternal age first birth, total fertility rate differs substantially between low‐ middle‐resource countries upon which most evidence based. Methods To...
Gestational weight gain may be a modifiable contributor to infant health outcomes, but the effect of gestational duration on has limited identification optimal ranges. Recently developed z-score and percentile charts can used classify independent duration. However, racial/ethnic variation in possibility that differs among groups could affect generalizability charts. The objectives this study were (1) apply two different U.S. populations as an assessment generalisability (2) determine whether...
Abstract Background Current pregnancy weight gain guidelines were developed based on implicit assumptions of a small group experts about the relative seriousness adverse health outcomes. Therefore, they will not necessarily reflect values women. Objective To estimate 11 maternal and child outcomes that have been consistently associated with by engaging patients professionals. Methods We collected data using an online panel approach modified Delphi structure. selected purposeful sample...
Abstract Background The external validity of randomised trials can be compromised when trial participants differ from real‐world populations. In the Antenatal Late Preterm Steroids (ALPS) antenatal corticosteroids at late preterm ages, had systematically younger gestational ages than those outside setting. As risk respiratory morbidity (the primary outcome) is higher gestations, absolute benefits calculated in population may overestimate treatment benefits. Objectives To estimate reduction...
Abstract Background Previous studies have demonstrated that short interpregnancy interval (the between delivery and estimated last menstrual period of a subsequent pregnancy) is associated with small for gestational age birth. It controversial if this association causal, as few accounted likely confounding factors such unintended pregnancy. We examined the infant birthweight, adjusting pregnancy intention other socio‐economic obstetrical risk factors. Methods used data from Scandinavian...
Abstract Background The fullPIERS risk prediction model was developed to identify which women admitted with confirmed diagnosis of preeclampsia are at highest developing serious maternal complications. discriminates well between who develop (vs. those do not) adverse outcomes. It has been externally validated in several populations. We assessed whether placental growth factor (PlGF), a biomarker associated risk, adds incremental value the model. Methods Using cohort into tertiary hospitals...
Abstract Background Placental abnormalities have been described in clinical convenience samples, with predominately adverse outcomes. Few studies placental patterns unselected samples. Objective We aimed to investigate associations between co‐occurring features and pregnancy outcomes a prospective cohort of singletons. Methods Data were from the Safe Passage study (U.S. South Africa, 2007–2015). Before 24 weeks' gestation, participants randomly invited donate tissue at delivery for blinded,...
<b><i>Objective:</i></b> Epilepsy is one of the most common chronic neurologic diseases in children; however, few recent studies examine prevalence epilepsy and its evolution over time according to birth or maternal characteristics. The aim study was children born between 2002 2020 temporal trends by year birth, Ontario, Canada, overall, <b><i>Methods:</i></b> We included all in-hospital deliveries (<i>N</i> = 2,343,482) using...
Dietary supplements including vitamins, minerals, and natural health products are commonly consumed by those aiming to optimize fertility pregnancy outcomes. The aim of this survey was describe supplementation practices among individuals who were pregnant or trying conceive in Vancouver, Canada. An online conducted 500 ( n = 250) 250). Participants met a substantial proportion vitamin mineral recommendations through alone. Exceptions included calcium, magnesium, choline, with median...
The Society for Maternal-Fetal Medicine recommends defining fetal growth restriction as an estimated weight or abdominal circumference <10th percentile of a population-based reference. However, because multiple references are available, understanding their ability to identify infants at increased risk due is critical. Previous studies have focused on the different population short-term outcomes, but also has longer-term consequences child development.