A5101573041- Catalytic Processes in Materials Science
- Alzheimer's disease research and treatments
- Catalysis and Hydrodesulfurization Studies
- Supramolecular Self-Assembly in Materials
- biodegradable polymer synthesis and properties
- Zeolite Catalysis and Synthesis
- Catalysis for Biomass Conversion
- Protein Structure and Dynamics
- Granular flow and fluidized beds
- Catalysis and Oxidation Reactions
- Catalysts for Methane Reforming
- Mesoporous Materials and Catalysis
- Polymer Nanocomposites and Properties
- Nanomaterials for catalytic reactions
- Organometallic Complex Synthesis and Catalysis
- Process Optimization and Integration
- Metal-Organic Frameworks: Synthesis and Applications
- Layered Double Hydroxides Synthesis and Applications
- Smart Grid Energy Management
- Advanced Polymer Synthesis and Characterization
- Bamboo properties and applications
- Synthetic Organic Chemistry Methods
- Lipid Membrane Structure and Behavior
- Advanced Multi-Objective Optimization Algorithms
- Advanced Materials and Mechanics
Zhejiang University
2009-2023
Hangzhou Xixi hospital
2015-2020
University of Akron
2015-2018
State Key Laboratory of Chemical Engineering
2007-2017
Hangzhou Academy of Agricultural Sciences
2016
Alzheimer's disease (AD) and type 2 diabetes (T2D) are two common protein misfolding diseases. Increasing evidence suggests that these diseases may be correlated with each other via cross-sequence interactions between β-amyloid peptide (Aβ) associated AD human islet amyloid polypeptide (hIAPP) T2D. However, little is known about how peptides work they interact to induce amyloidogenesis. In this work, we study the effect of Aβ hIAPP on hybrid structures, conformational changes, aggregation...
Significant efforts have been made to develop highly tough hydrogels towards many scientific and industrial applications. However, most of the as-prepared lose their mechanical strength toughness when they swell in aqueous solution. Current knowledge about swelling-induced property changes mainly stems from single-network (SN) chemically linked double-network (DN) hydrogels, but little is known swelling properties hybrid physically-chemically DN gels. Here, we synthesized agar/PAM combining...
HP-β-CD are not only nontoxic to cells, but also greatly inhibits Aβ fibrillization and reduces Aβ-induced toxicity<italic>via</italic>its inner cavity.
Amyloid-β (Aβ) and human islet polypeptide (hIAPP) are the causative agents responsible for Alzheimer's disease (AD) type II diabetes (T2D), respectively. While numerous studies have reported cross-seeding behavior of Aβ hIAPP in solution, little effort has been made to examine presence cell membranes, which is more biologically relevant pathological link between AD T2D. In this work, we computationally study adsorption behaviors on zwitterionic POPC anionic...
Interaction of catalysts' active sites with CO<sub>2</sub>affected the aromatics yield MTA reaction over modified catalysts in a CO<sub>2</sub>atmosphere.
Ketonization of carboxylic acids provides an attractive way for upgrading biomass feedstocks into biofuels.
The promotional effect of Ti doping on the ketonization acetic acid over a CeO<sub>2</sub> catalyst was investigated.
Amyloid peptides can misfold and aggregate into amyloid oligomers fibrils containing conformationally similar β-sheet structures, which are linked to the pathological hallmark of many neurodegenerative diseases. These β-sheet-rich aggregates provide common structural motifs accelerate formation by acting as seeds. However, little is known about how one peptide aggregation will affect another (namely, cross-seeding). In this work, we studied cross-seeding possibility efficiency between rat...
Abstract The misfolding and aggregation of proteins peptides into amyloid fibrils are believed to be responsible for the dysfunction death neuron cells in many neurodegenerative diseases. Resolving atomic structures at different stages by molecular simulations has opened new ways probe mechanisms aggregation, toxicity, inhibition, as well validate computational data with available experimental ones. In this review article, we summarize some recent important findings on: 1) a number oligomers...
The co-reaction method provides an efficient strategy for methane conversion under mild conditions, which is of urgent importance direct valorization natural gas to liquid hydrocarbons.
Thiol could bond to the surface, mitigating oxidation by HCl and protecting active structure of Au NPs.
Spherical and well-dispersed silica/poly[styrene-co-(acrylic acid)] (SiO2/PSA) core–shell particles have been synthesized using an improved phase-inversion process. The resulting were successfully used as supports for polyolefin catalysts in the production of polyethylene with broad molecular weight distribution. Through vapor phase, instead liquid phase traditional process, a non-solvent was introduced into mixture micrometer-sized SiO2 PSA solution. structure SiO2/PSA microspheres...
Abstract Novel exfoliated polyethylene (PE)/palygorskite nanocomposites prepared by in situ polymerization are characterized solid‐state nuclear magnetic resonance (NMR). The phase structure and molecular mobility investigated a combination of proton carbon NMR. results showed that incorporation small amounts palygorskite had great influence on the mobility. incorporated hindered crystallization process introduced motion‐hindered chains NMR crystalline amorphous phase. 13 C...
Limited by harsh reaction conditions, the activation and utilization of methane were regarded as holy grail reaction. Co-reaction with methanol, successfully realizing mild conversion below 450 °C, provides practical strategies for on metal-loaded ZSM-5 zeolites, especially highly efficient Zn loaded ones. However, species, active acid sites zeolite, have not been sufficiently studied. In this paper, Zn-loaded zeolite was prepared, modified capacity, loading strategy, treating atmosphere....