A5011349209- Circadian rhythm and melatonin
- Electrocatalysts for Energy Conversion
- Porphyrin and Phthalocyanine Chemistry
- Electrochemical Analysis and Applications
- Neurobiology and Insect Physiology Research
- Fuel Cells and Related Materials
- Neuroendocrine regulation and behavior
- Genetics, Aging, and Longevity in Model Organisms
- Hormonal and reproductive studies
- Immune Cell Function and Interaction
- Immune Response and Inflammation
- Physiological and biochemical adaptations
- Adipose Tissue and Metabolism
- Osteoarthritis Treatment and Mechanisms
- Inflammatory mediators and NSAID effects
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Cholinesterase and Neurodegenerative Diseases
- Cancer, Stress, Anesthesia, and Immune Response
- Nerve injury and regeneration
- Inflammasome and immune disorders
- Rabbits: Nutrition, Reproduction, Health
- Vitamin C and Antioxidants Research
- Erythrocyte Function and Pathophysiology
- Semiconductor materials and devices
- Cytokine Signaling Pathways and Interactions
Banaras Hindu University
1975-2024
Institute of Zoology
2024
Gajara Raja Medical College
2006-2024
Batumi Shota Rustaveli State University
2019
Regional Centre for Biotechnology
2018-2019
Case Western Reserve University
1984-2006
Pediatrics and Genetics
2005
University School
2001
University of Calcutta
1967
Iron(III) tetramethoxyphenyl porphyrin chloride adsorbed on the Black Pearls carbon (FeTMPP‐Cl/BP) was heat‐treated at temperatures from 200 to 1000°C in Ar atmosphere and characterized by using cyclic voltammetry, X‐ray photoelectron spectroscopy (XPS), transmission electron microscopy (TEM) techniques. Cyclic voltammetry experiments were carried out acidic alkaline solutions. Redox peaks due Fe(III)/Fe(II) reaction present an unheat‐treated sample 200°C but significantly reduced height for...
To determine the source(s) of blood and very low density lipoprotein (VLDL)-triglyceride glycerol during fasting, four men ingested 2 H O from 14 to 20 h into a 60-h fast achieve ∼0.5% body water enrichment. At 60 flux was measured using [2- C]glycerol. Blood taken for measurement enrichment at carbon 6 glucose 3 free VLDL-triglyceride glycerol. hydrogens bound 105 ± 2% glucose, indicating isotopic equilibrium between hepatic glyceraldehyde 3- P P. The 17 3% glycerol, that significant...
Age-dependent declining level of melatonin induces free radical load and thereby deteriorates immune function. However, reports are lacking about age-dependent membrane receptor (MT1 & MT2) expression, their role in regulation reactive nitrogen species (RNS) eventually how they affect immunity a tropical rodent F. pennanti. We checked MT1R, MT2R iNOS expression lymphoid organs young middle old aged squirrels. Nitrite nitrate ion concentration (NOx) organs, testes plasma, lymphocyte...
Despite the evidence for melatonin membrane receptors (MT1R and MT2R) on lymphoid tissues in a wide range of seasonal breeders, their specific potency has never been compared correlated with cell-mediated immunity.We used luzindole, nonselective MT2R antagonist, 4-phenyl-2-propionamidotetralin (4P-PDOT), selective to assess MT1 MT2 melatonin-induced immunity under both vivo as well vitro conditions.Physiological doses (25 μg/100 g body weight 100 500 pg/ml vitro) upregulated MT1R expression...
Summary Neutrophils maintain immune homeostasis by engulfing apoptotic cells and debris. We describe the rapid activation of neutrophils after hemoglobin (Hb)-activated platelets, which are abundant in circulation hemolytic patients. from healthy individuals Hb-activated platelets express elevated CD11b secrete significant amounts tumor necrosis factor (TNF)-α, interleukin (IL)-1β, IL-6, myeloperoxidase (MPO) elastase within 4-h but not with free-Hb only vitro. These exhibit early onset...
Knee osteoarthritis (OA) is a prevalent degenerative joint disorder causing pain, stiffness, and reduced function, significantly impacting the quality of life. Current treatments mainly provide symptomatic relief, with limited efficacy in halting disease progression. Platelet-rich plasma (PRP), biological therapy rich growth factors, has gained attention as potential treatment for knee OA due to its regenerative properties. This study evaluates PRP managing primary OA.
Abstract The distinct response shown by different phenotypes of macrophages and monocytes under various clinical conditions has put the heterogeneity these cells into focus investigation for several diseases. Recently, we have described that after engulfing hemoglobin (Hb)‐activated platelets, classical differentiated pro‐inflammatory phenotypes, which were abundant in circulation paroxysmal nocturnal hemoglobinuria (PNH) sickle cell disease patients. Our current study shows upon engulfment...
Traumatic or inflammatory injury associates with deactivation of monocytes and impaired synthesis proinflammatory cytokines. We conducted a prospective, observational study to test whether cardiac surgery additionally dendritic natural killer (NK) cell functions responsible for innate immune production interleukin (IL)-12-dependent interferon (IFN)-gamma in response bacteria toll-like receptor agonists. Blood samples were taken just before induction anesthesia 24 h postoperatively. LPS-...
Ampicillin is one of the most commonly prescribed antibiotics against intra-renal infections. Prolonged use ampicillin has been found to be associated with a high rate free-radical generation and oxidative stress induced nephrotoxicity. In present study, we report comparative effects melatonin vitamin-C (Vit-C) in ameliorating biochemical structural alterations renal tissues caused by sodium. Biochemical parameters such as acid phosphatase (ACP), alkaline (ALP), creatinine urea levels urine...